Characterization of the S272A,D site-directed mutations of O-Acetylserine sulfhydrylase: Involvement of the pyridine ring in the α,β-elimination reaction

Biochemistry

Volumn 42, Issue 1, 2003, Pages 106-113

  Daum, Sebastian ^a,b   Tai, Chia Hui ^a,c   Cook, Paul F ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

^b MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^c CHENG SHIU UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PYRIDINE RING;

ENERGY TRANSFER; FLUORESCENCE; HYDROGEN BONDS; MUTAGENESIS; RESONANCE;

ENZYMES;

CYSTEINE SYNTHASE;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CIRCULAR DICHROISM; ENZYME MECHANISM; HYDROGEN BOND; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ALANINE; ASPARTIC ACID; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; CYSTEINE SYNTHASE; DEUTERIUM; HYDROGEN BONDING; KINETICS; MUTAGENESIS, SITE-DIRECTED; PYRIDINES; PYRIDOXAL PHOSPHATE; SERINE; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY;

EID: 0037435585     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0268044     Document Type: Article

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