Cloning of the conserved regulatory operon by its aerial mycelium-inducing activity in an amfR mutant of Streptomyces griseus

Gene

Volumn 306, Issue 1-2, 2003, Pages 79-89

  Komatsu, Mamoru ^a   Kuwahara, Yoshitaka ^a   Hiroishi, Ayako ^a   Hosono, Kuniaki ^a   Beppu, Teruhiko ^a   Ueda, Kenji ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

amfR; Cellular differentiation; Conservon; Glucose repression; Streptomyces griseus

Indexed keywords

CYTOCHROME P450; DNA FRAGMENT; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; RAS PROTEIN;

ARTICLE; BACTERIAL GENOME; BACTERIUM MUTANT; GENE ACTIVITY; GENETIC CONSERVATION; MOLECULAR CLONING; MYCELIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; STREPTOMYCES GRISEUS;

EUKARYOTA; STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCES GRISEUS;

EID: 0037434959     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(03)00405-0     Document Type: Article

References (30)

1. Beck E., Ludwig G., Auerswald E.A., Reiss B., Schaller H. Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5. Gene. 19:1982;327-336.
2. Bentley S.D., et al. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature. 417:2002;141-147.
3. Bourn W.R., Babb B. Computer assisted identification and classification of streptomycete promoters. Nucleic Acids Res. 23:1995;3696-3703.
4. Brady A.E., Limbird L.E. G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction. Cell Signal. 14:2002;297-309.
5. Bystrykh L.V., Fernandez-Moreno M.A., Herrema J.K., Malpatida F., Hopwood D.A., Dijkhuizen L. Production of actinorhodin-related 'blue' pigments by Streptomyces coelicolor A3(2). J. Bacteriol. 178:1996;2238-2244.
6. Chater K.F. Taking a genetic scalpel to the Streptomyces colony. Microbiology. 144:1998;1465-1478.
7. Chen H.P., Walker G.C. Succinoglycan production by Rhizobium meliloti is regulated through the ExoS-ChvI two-component regulatory system. J. Bacteriol. 180:1998;20-26.
8. Elliot M.A., Bibb M.J., Buttner M.J., Leskiw B.K. BldD is a direct regulator of key developmental genes in Streptomyces coelicolor A3(2). Mol. Microbiol. 40:2001;257-269.
9. Horinouchi S., Kumada Y., Beppu T. Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: cloning and characterization. J. Bacteriol. 158:1984;481-487.
10. Hu H., Zhang Q., Ochi K. Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase β subunit) of Streptomyces lividans. J. Bacteriol. 184:2002;3984-3991.
11. Kakinuma S., Takada Y., Ikeda H., Tanaka H., O S. Cloning of a large DNA fragments, which hybridize with actinorhodin biosynthesis genes, from kalafungin and nanaomycin A methyl ester producers and identification of genes for kalafungin biosynthesis of the kalafungin producer. J. Antibiot. 44:1991;995-1005.
12. Kang D.K., Li X.M., Ochi K., Horinouchi S. Possible involvement of cAMP in aerial mycelium formation and secondary metabolism in Streptomyces griseus. Microbiology. 145:1999;1161-1172.
13. Katz E., Thompson C.J., Hopwood D.A. Cloning and expression of tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans. J. Gen. Microbiol. 129:1983;2703-2714.
14. Kieser T., Bibb M.J., Buttner M.J., Chater K., Hopwood D.A. Practical Streptomyces Genetics. 2000;John Innes Foundation, Norwich, UK.
15. Kyte J., Doolitle R.F. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:1982;105-132.
16. Maniatis T., Fritsch E.F., Sambrook J. Molecular Cloning: A Laboratory Manual. 1982;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
17. Miyadoh S. Research on antibiotic screening in Japan over the last decade: a producing microorganisms approach. Actinomycetologica. 7:1993;100-106.
18. Ohnishi Y., Kameyama S., Onaka H., Horinouchi S. The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus: identification of a target gene of the A-factor receptor. Mol. Microbiol. 34:1999;102-111.
19. Shinkawa H., Hatada Y., Okada M., Kinashi H., Nimi O. Nucleotide sequence of a principal sigma factor gene (hrdB) of Streptomyces griseus. J. Biochem. 118:1995;494-499.
20. Süsstrunk U., Pidoux J., Taubert S., Ullmann A., Thompson C.J. Pleiotropic effects of cAMP on germination, antibiotic biosynthesis and morphological development in Streptomyces coelicolor. Mol. Microbiol. 30:1998;33-46.
21. Ueda K., Miyake K., Horinouchi S., Beppu T. A gene cluster involved in aerial mycelium formation in Streptomyces griseus encodes proteins similar to the response regulators of two-component regulatory systems and membrane translocators. J. Bacteriol. 175:1993;2006-2016.
22. Ueda K., Umeyama T., Beppu T., Horinouchi S. The aerial mycelium-defective phenotype of Streptomyces griseus resulting from A-factor deficiency is suppressed by a Ser/Thr kinase of S. coelicolor A3(2). Gene. 169:1996;91-95.
23. Ueda K., Hsheh C.-W., Tosaki T., Shinakawa H., Beppu T., Horinouchi S. Characterization of an A-factor-responsive repressor for amfR essential for onset of aerial mycelium formation in Streptomyces griseus. J. Bacteriol. 180:1998;5085-5093.
24. Umeyama T., Horinouchi S. Autophosphorylation of a bacterial serine/threonine kinase, AfsK, is inhibited by KbpA, an AfsK-binding protein. J. Bacteriol. 183:2001;5506-5512.
25. Umeyama T., Lee P.C., Ueda K., Horinouchi S. An AfsK-AfsR system involved in the response to aerial mycelium formation to glucose in Streptomyces griseus. Microbiology. 145:1999;2281-2292.
26. Waters B., Vujaklija D., Gold M.R., Davies J. Protein tyrosine phosphorylation in streptomycetes. FEMS Microbiol. Lett. 120:1994;187-190.
27. Welton R.M., Hoffman C.S. Glucose monitoring in fission yeast via the Gpa2 galpha, the git5 Gbeta and the git3 putative glucose receptor. Genetics. 156:2000;513-521.
28. Williams S.B., Stewart V. Nitrate- and nitrite-sensing protein NarX of Escherichia coli K-12: mutational analysis of the amino-terminal tail and first transmembrane segment. J. Bacteriol. 179:1997;721-729.
29. Xue Y., Zhao L., Liu H.W., Sherman D.H. A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity. Proc. Natl. Acad. Sci. USA. 95:1998;12111-12116.
30. AdsA) that is essential for morphological development in Streptomyces griseus. J. Bacteriol. 182:2000;4596-4605.