Quantitative structure-activity relationships predict the delayed neurotoxicity potential of a series of o-alkyl-o-methylchloroformimino phenylphosphonates

Journal of Toxicology and Environmental Health - Part A

Volumn 66, Issue 7, 2003, Pages 611-625

  Malygin, Vladimir V ^a   Sokolov, Vladimir B ^a   Richardson, Rudy J ^b   Makhaeva, Galina F ^a  

^a INSTITUTE OF PHYSIOLOGICALLY ACTIVE COMPOUNDS   (Russian Federation)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; METHYL GROUP; NEUROTOXIC ESTERASE; O METHYLCHLOROFORMIMINOPHENYLPHOSPHONATE; ORGANOPHOSPHATE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE; ENZYME INHIBITION; FEMALE; HEN; LD 50; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT;

ALKANES; ANIMALS; CARBOXYLIC ESTER HYDROLASES; CHICKENS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; LETHAL DOSE 50; NEUROTOXICITY SYNDROMES; ORGANOPHOSPHORUS COMPOUNDS; PREDICTIVE VALUE OF TESTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RISK ASSESSMENT; TIME FACTORS;

ANIMALIA;

EID: 0037432753     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390309353770     Document Type: Article

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