Polyamine biosynthesis inhibition enhances HSV-1 thymidine kinase/ganciclovir-mediated cytotoxicity in tumor cells

International Journal of Cancer

Volumn 104, Issue 3, 2003, Pages 380-388

  Pasanen, Tiina ^a   Karppinen, Anne ^a   Alhonen, Leena ^a   Jänne, Juhani ^a   Wahlfors, Jarmo ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Cancer; DFMO; Gene therapy; Herpes simplex virus thymidine kinase; Lentivirus vector; Polyamines

Indexed keywords

EFLORNITHINE; GANCICLOVIR; POLYAMINE; THYMIDINE KINASE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER THERAPY; CELL CYCLE S PHASE; CELL GROWTH; CELL TYPE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DRUG EFFICACY; DRUG TOLERABILITY; GLIOMA CELL; HERPES SIMPLEX VIRUS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN SYNTHESIS INHIBITION; VIRAL GENE THERAPY; VIRUS GENE;

ANIMALS; ANTIVIRAL AGENTS; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; EFLORNITHINE; ENZYME INHIBITORS; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; GLIOMA; HERPESVIRUS 1, HUMAN; HUMANS; MALE; POLYAMINES; PROSTATIC NEOPLASMS; RATS; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 0037431431     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10942     Document Type: Article

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