Spinal adenosine agonist reduces c-fos and astrocyte activation in dorsal horn of rats with adjuvant-induced arthritis

Neuroscience Letters

Volumn 340, Issue 2, 2003, Pages 119-122

  Sorkin, Linda S ^a   Maruyama, Karly ^a   Boyle, David L ^b   Yang, Li ^b   Marsala, Martin ^a   Firestein, Gary S ^b  

^a University of California at San Diego   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenosine; Adjuvant induced arthritis; c Fos; Glia; Inflammation

Indexed keywords

ADENOSINE RECEPTOR STIMULATING AGENT; GLIAL FIBRILLARY ACIDIC PROTEIN; PROTEIN C FOS; SODIUM CHLORIDE;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BASEMENT MEMBRANE; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFECT; IMMUNOREACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD DORSAL HORN;

EID: 0037430888     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00082-X     Document Type: Article

References (13)

1. Abbadie C., Besson J.M. c-fos expression in rat lumbar spinal cord during the development of adjuvant-induced arthritis. Neuroscience. 48:1992;985-993.
2. Abbadie C., Besson J.M. Chronic treatments with aspirin or acetaminophen reduce both the development of polyarthritis and Fos-like immunoreactivity in rat lumbar spinal cord. Pain. 57:1994;45-54.
3. Abbadie C., Besson J.M., Calvino B. c-Fos expression in the spinal cord and pain-related symptoms induced by chronic arthritis in the rat are prevented by pretreatment with Freund adjuvant. J. Neurosci. 14:1994;5865-5871.
4. Bao L., Zhu Y., Elhassan A.M., Wu Q., Xiao B., Zhu J., Lindgren J.U. Adjuvant-induced arthritis: IL-1 beta, IL-6 and TNF-alpha are up-regulated in the spinal cord. NeuroReport. 12:2001;3905-3908.
5. Bong G.W., Rosengren S., Firestein G.S. Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation: the role of N-methyl-D-aspartate receptors. J. Clin. Invest. 98:1996;2779-2785.
6. Boyle D.L., Moore J., Yang L., Sorkin L.S., Firestein G.S. Stimulation of spinal adenosine (ADO) receptors inhibits rat adjuvant arthritis. Arthritis Rheum. 44:2001;1307.
7. Garrison C.J., Dougherty P.M., Carlton S.M. GFAP expression in lumbar spinal cord of naïve and neuropathic rats treated with MK-801. Exp. Neurol. 129:1994;237-243.
8. Kehl L.J., Gogas K.R., Lichtblau L., Pollock C.H., Mayes M., Basbaum A.I., Wilcox G.L. The NMDA antagonist MK801 reduces noxious stimulus-evoked FOS expression in the spinal cord dorsal horn. Bond M.R., Charlton J.E., Woolf C.J. Proceedings of the VIth World Congress on Pain. Vol. 4:1991;Elsevier, Amsterdam.
9. Orendácová J., Marsala M., Sulla I., Kafka J., Jalc P., Cizková D., Taira Y., Marsala J. Incipient cauda equina syndrome as a model of somatovisceral pain in dogs: spinal cord structures involved as revealed by the expression of c-fos and NADPH diaphorase activity. Neuroscience. 95:2000;543-557.
10. Sagen J., Wang H. Adrenal medullary grafts suppress c-fos induction in spinal neurons of arthritic rats. Neurosci. Lett. 192:1995;181-184.
11. Watkins L.R., Milligan E.D., Maier S.F. Glial activation: a driving force for pathological pain. Trends Neurosci. 24:2001;450-455.
12. Yaksh T.L., Rudy T.A. Chronic catheterization of the spinal subarachnoid space. Physiol. Behav. 17:1976;1031-1036.
13. Yang L.C., Marsala M., Orendacova J., Yaksh T.L. Knee joint inflammation attenuates spinal FOS expression after unilateral paw formalin injection in rat. Neurosci. Lett. 225:1997;89-92.