The use of sulfonylamido pyrimidines incorporating an unsaturated side chain as endothelin receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 5, 2003, Pages 955-959

  Bolli, Martin H ^a   Boss, Christoph ^a   Clozel, Martine ^a   Fischli, Walter ^a   Hess, Patrick ^a   Weller, Thomas ^a  

^a ACTELION PHARMACEUTICALS LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BOSENTAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; PYRIMIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BLOOD PRESSURE; CHO CELL; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG STRUCTURE; IC 50; NONHUMAN; RECEPTOR BLOCKING;

EID: 0037430449     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)01084-3     Document Type: Article

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