Tolerance and dependence following chronic intracerebroventricular infusions of Tyr-D-Arg2-Phe-Sar4 (TAPS)

European Journal of Pharmacology

Volumn 459, Issue 1, 2003, Pages 41-48

  Vonhof, Stefan ^a   Gudka, Bijal D ^b   Sirén, Anna Leena ^b,c  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Antinociception; Dermorphin; TAPS (Tyr D Arg2 Phe Sar4); Tetrapeptide; Tolerance; Withdrawal

Indexed keywords

DERMORPHIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MORPHINE SULFATE; MU OPIATE RECEPTOR AGONIST; NALOXONE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG CROSS TOLERANCE; DRUG INFUSION; DRUG TOLERANCE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; INFUSION PUMPS; INJECTIONS, INTRAVENTRICULAR; MALE; MORPHINE; NALOXONE; OLIGOPEPTIDES; PAIN; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS; TIME FACTORS;

EID: 0037427946     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02822-4     Document Type: Article

References (20)

1. Broccardo M., Erspamer V., Falconieri Erspamer G., Improta G., Linari G., Melchiorri P., Montecucchi P.C. Pharmacological data on dermorphins, a new class of potent opioid peptides from amphibian skin. Br. J. Pharmacol. 73:1981;625-631.
2. Frederickson R.C., Smits S.E. Time course of dependence and tolerance development in rats treated with "slow release" morphine suspensions. Res. Commun. Chem. Pathol. Pharmacol. 5:1973;867-870.
3. Giagnoni G., Mennuni L., Pecora N., Basilico L., Parolaro D., Gori E. Binding studies of dermorphin and its L-form on rat brain opioid receptors. Pharmacol. Res. Commun. 19:1987;173-181.
4. Goodman R.R., Pasternak G.W. Visualization of mu1 opiate receptors in rat brain by using a computerized autoradiographic subtraction technique. Proc. Natl. Acad. Sci. U. S. A. 82:1985;6667-6671.
5. Guglietta A., Irons B.J., Lazarus L.H., Melchiorri P. Structure-activity relationship of dermorphin on gastric secretion. Endocrinology. 120:1987;2137-2143.
6. Lazarus L.H., Guglietta A., Wilson W.E., Irons B.J., de Castiglione R. Dimeric dermorphin analogues as mu-receptor probes on rat brain membranes. Correlation between central mu-receptor potency and suppression of gastric acid secretion. J. Biol. Chem. 264:1989;354-362.
7. Ling G.S., MacLeod J.M., Lee S., Lockhart S.H., Pasternak G.W. Separation of morphine analgesia from physical dependence. Science. 226:1984;462-464.
8. Montecucchi P.C., de Castiglione R., Piani S., Gozzini L., Erspamer V. Amino acid composition and sequence of dermorphin, a novel opiate-like peptide from the skin of Phyllomedusa sauvagei. Int. J. Pept. Protein Res. 17:1981;275-283.
9. 4]-dermorphin (1-4) in the rat. Pharmacol. Biochem. Behav. 24:1986;27-31.
10. Paakkari P., Paakkari I., Sirén A.L., Feuerstein G. Respiratory and locomotor stimulation by low doses of dermorphin, a mu1 receptor-mediated effect. J. Pharmacol. Exp. Ther. 252:1990;235-240.
11. 2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors. J. Pharmacol. Exp. Ther. 266:1993;544-550.
12. Pasternak G.W. Incomplete cross tolerance and multiple mu opioid peptide receptors. Trends Pharmacol. Sci. 22:2001;67-70.
13. Pasternak G.W., Wood P.J. Multiple mu opiate receptors. Life Sci. 38:1986;1889-1898.
14. 2]-dermorphin tetrapeptide analogue and morphine. Neuropharmacology. 32:1993;689-693.
15. 2-dermorphin tetrapeptide analogs: a potent and long-lasting analgesic activity after subcutaneous administration. Biochem. Biophys. Res. Commun. 120:1984;214-218.
16. 2-substituted tetrapeptides. J. Pharmacol. Exp. Ther. 242:1987;654-659.
17. 4 activates phospholipase C-coupled mu2-opioid receptors in SH-SY5Y cells. Eur. J. Pharmacol. 305:1996;235-238.
18. Stevens C.W., Yaksh T.L. Spinal action of dermorphin, an extremely potent opioid peptide from frog skin. Brain Res. 385:1986;300-304.
19. Stevens C.W., Yaksh T.L. Time course of tolerance development to continuously infused antinociceptive agents in rat spinal cord. J. Pharmacol. Exp. Ther. 251:1989;216-223.
20. 2-Phe-Sar (TAPS). Eur. J. Pharmacol. 416:2001;83-93.