Levels and behavior of 2-phenylbenzotoriazole-type mutagens in the effluent of a sewage treatment plant

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 534, Issue 1-2, 2003, Pages 123-132

  Morisawa, Tamie ^a   Mizuno, Tomoko ^a   Ohe, Takeshi ^a   Watanabe, Tetsushi ^b   Hirayama, Teruhisa ^b   Nukaya, Haruo ^c   Shiozawa, Tatsushi ^c   Terao, Yoshiyasu ^c   Sawanishi, Hiroyuki ^d   Wakabayashi, Keiji ^e  

^a KYOTO WOMEN'S UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d HOKURIKU UNIVERSITY   (Japan)

^e NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Blue rayon; Effluent; Mutagenicity; PBTA; Sewage treatment plant

Indexed keywords

2 [2 (ACETYLAMINO) 4 [(2 HYDROXYETHYL)AMINO] 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 [2 (ACETYLAMINO) 4 [BIS(2 HYDROXYETHYL)AMINO] 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 [2 (ACETYLAMINO) 4 [BIS(2 METHOXYETHYL)AMINO] 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 [2 (ACETYLAMINO) 4 [N (2 CYANOETHYL)ETHYLAMINO] 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 [2 (ACETYLAMINO) 4 AMINO 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 [4 [BIS(2 ACETOXYETHYL)AMINO] 2 (ACETYLAMINO) 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; METHANOL; MUTAGENIC AGENT; SURFACE WATER; UNCLASSIFIED DRUG;

ADSORPTION; AMES TEST; ARTICLE; DECOMPOSITION; EFFLUENT; ELECTROCHEMISTRY; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MUTAGENICITY; PRIORITY JOURNAL; RIVER ECOSYSTEM; SALMONELLA TYPHIMURIUM; SEWAGE TREATMENT; WATER SAMPLING;

ENVIRONMENTAL MONITORING; JAPAN; MUTAGENICITY TESTS; MUTAGENS; SALMONELLA TYPHIMURIUM; SEWAGE; TRIAZOLES; WASTE DISPOSAL, FLUID; WATER POLLUTANTS, CHEMICAL;

GOSSYPIUM HIRSUTUM; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0037427844     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(02)00253-X     Document Type: Article

References (22)

1. Claxton L.D., Houk V.S., Hughes T.J. Genotoxicity of industrial waste and effluents. Mutat. Res. 410:1998;237-243.
2. Houk V.S. The genotoxicity of industrial wastes and effluents - a review. Mutat. Res. 277:1992;91-138.
3. White P.A., Rasmussen J.B. The genotoxic hazards of domestic wastes in surface waters. Mutat. Res. 410:1998;223-236.
4. White P.A., Rasmussen J.B., Blaise C. Comparing the presence, potency, and potential hazard of genotoxins extracted from a broad range of industrial effluents. Environ. Mol. Mutagen. 27:1996;116-139.
5. Paxéus N., Schröder H.F. Screening for non-regulated organic compounds in municipal wastewater in Göteborg, Sweden. Water Sci. Tech. 33:1996;9-15.
6. Nukaya H., Yamashita J., Tsuji K., Terao Y., Ohe T., Sawanishi H., Katsuhara T., Kiyokawa K., Tezuka M., Oguri A., Sugimura T., Wakabayashi K. Isolation and chemical-structural determination of a novel aromatic amine mutagen in water from the Nishitakase River in Kyoto. Chem. Res. Toxicol. 10:1997;1061-1066.
7. Shiozawa T., Muraoka K., Nukaya H., Ohe T., Sawanishi H., Oguri A., Wakabayashi K., Sugimura T., Terao Y. Chemical sysnthesis of a novel aromatic amine mutagen isolated from water of the Nishitakase River in Kyoto and a possible route of its formation. Chem. Res. Toxicol. 11:1998;375-380.
8. Tada A., Shiozawa T., Muraoka K., Terao Y., Nukaya H., Yamashita J., Ohe T., Sawanishi H., Katsuhara T., Sugimura T., Wakabayashi K. Identification of a 2-phenylbenzotriazole (PBTA)-type mutagen, PBTA-2, in water from the Nishitakase River in Kyoto. Chem. Res. Toxicol. 11:1998;1195-1200.
9. Shiozawa T., Tada A., Nukaya H., Watanabe T., Takahashi Y., Asanoma M., Ohe T., Sawanishi H., Katsuhara T., Sugimura T., Wakabayashi K., Terao Y. Isolation and identification of a new 2-phenylbenzotriazole-type mutagen (PBTA-3) in the Nikko River in Aichi. Chem. Res. Toxicol. 13:2000;535-540.
10. Nukaya H., Shiozawa T., Tada A., Tearo Y., Ohe T., Watanabe T., Asanoma M., Sawanishi H., Katsuhara T., Sugimura T., Wakabayashi K. Identification of 2-[2-(acetylamino)-4-amino-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H- benzotriazole (PBTA-4) as a potent mutagen in river water in Kyoto and Aichi prefectures, Japan. Mutat. Res. 492:2001;73-80.
11. Watanabe T., Nukaya H., Terao Y., Tada A., Sawanishi H., Ohe T., Takahashi T., Hirayama T., Sugimura T., Wakabayashi K. Synthesis of 2-phenylbenzo-triazole-type mutagens, PBTA-5 and PBTA-6, and their detection in waters from rivers in Japan. Mutat. Res. 498:2001;107-115.
12. Ohe T., Takeuchi N., Watanabe T., Tada A., Nukaya H., Terao Y., Nukaya H., Sawanishi H., Hirayama T., Sugimura T., Wakabayashi K. Quantification of two aromatic amine mutagens, PBTA-1 and PBTA-2, in the Yodo River system. Environ. Health Persp. 107:1999;701-704.
13. Sakamoto H., Hayatsu H. A simple method for monitoring mutagenicity of river water. Mutagens in Yodo River System, Kyoto-Osaka. Bull. Environ. Contam. Toxicol. 44:1990;521-528.
14. Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutat. Res. 113:1983;173-215.
15. Sayato Y., Nakamuro K., Ueno H., Goto R. Identification of polycyclic aromatic hydrocarbons in mutagenic adsorbents to a copper-phthalocyanine derivative recovered from municipal river water. Mutat. Res. 300:1993;207-213.
16. Kusamran W.R., Wakabayashi K., Oguri A., Tepsuwan A., Nagao M., Sugimura T. Mutagenicities of Bangkok and Tokyo river waters. Mutat. Res. 325:1994;99-104.
17. Ohe T., Ito H., Kawabuti M. Genotoxicity of blue rayon extracts from river waters using sister chromatid exchange in cultured mammalian cells. Arch. Environ. Contam. Toxicol. 25:1993;293-297.
18. Kira S., Nogami Y., Ito T., Hayatsu H. Detection of benzo(a)pyrene and mutagenicity in water of Lake Baikal (Russia) and rivers in Okayama (Japan) using the blue rayon method: a simplified handling and transportation of samples from remote sites. Environ. Toxicol. 14:1999;279-284.
19. Goto S., Endo O., Matsumoto H., Sakai S., Akutagawa T., Asanoma M., Hirayama T., Watanabe T., Sera N., Tsukatani Y., Tada A., Wakabayashi K. Mutagenicity of airborne particle, river water and soil in Japan. Environ. Mutagen. Res. 22:2000;45-54.
20. T. Ohe, P.A. White, D.M. DeMarini, Mutagenic characteristics of river waters flowing through large metropolitan areas in North America, Mutat. Res., 534 (2003) 101-112.
21. Sakamoto H., Ohe T., Hayatsu T., Hayatsu H. Evaluation of blue-chitin column, blue-rayon hanging, and XAD-resin column techniques for concentrating mutagens from two Japanese rivers. Mutat. Res. 371:1996;79-85.
22. Watanabe T., Shiozawa T., Takahashi Y., Takahashi T., Terao Y., Nukaya H., Tada A., Takamura T., Sawanishi H., Ohe T., Hirayama T., Sugimura T., Wakabayashi K. Mutagenicity of two 2-phenylbenzotriazole derivatives, 2-[2-acetylamino]-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-7) and 2-[2-acetylamino]-4-(diallylamino)-5-methoxyphenyl]-5-amino-7-bromo-4- chloro-2H-benzotriazole (PBTA-8) and their detection in river water in Japan. Mutagenesis. 17:2002;293-299.