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Volumn 133, Issue 5-6, 2003, Pages 77-87

Thalidomide: From tragedy to promise

Author keywords

Contergan ; Immunomodulation; Thalidomide

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; ANTHRACYCLINE; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BUSULFAN; CARBOPLATIN; CARMUSTINE; CELECOXIB; CISPLATIN; COLCHICINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DACARBAZINE; DEXAMETHASONE; DOCETAXEL; ESTRAMUSTINE; FLUDARABINE; GEMCITABINE; IRINOTECAN; MELPHALAN; PACLITAXEL; PAMIDRONIC ACID; PENTOXIFYLLINE; PLACEBO; TEMOZOLOMIDE; THALIDOMIDE; TOPOTECAN; UNINDEXED DRUG;

EID: 0037425714     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (41)

References (104)
  • 1
    • 47349113508 scopus 로고
    • Thalidomide and congenital abnormalities
    • Mc Bride WG. Thalidomide and congenital abnormalities. Lancet 1961/II:1358.
    • (1961) Lancet , vol.2 , pp. 1358
    • Mc Bride, W.G.1
  • 2
    • 49749219257 scopus 로고
    • Thalidomide and congenital abnormalities
    • Lenz W. Thalidomide and congenital abnormalities. Lancet 1961;I:45.
    • (1961) Lancet , vol.1 , pp. 45
    • Lenz, W.1
  • 3
    • 0023789803 scopus 로고
    • A short history of thalidomide embryopathy
    • Lenz W. A short history of thalidomide embryopathy. Teratology 1988;38:203-15.
    • (1988) Teratology , vol.38 , pp. 203-215
    • Lenz, W.1
  • 4
    • 0001279438 scopus 로고
    • Hinweis auf eine derzeitige häufung hypound aplastischer fehlbildungen der gliedmassen
    • Wiedemann HR. Hinweis auf eine derzeitige Häufung hypound aplastischer Fehlbildungen der Gliedmassen. Med Welt 1988;37:1863.
    • (1988) Med Welt , vol.37 , pp. 1863
    • Wiedemann, H.R.1
  • 6
    • 0035240521 scopus 로고    scopus 로고
    • Thalidomide: When everything old is new again
    • Nirenberg A. Thalidomide: when everything old is new again. Clin J Oncol Nurs 2001;5:15-8.
    • (2001) Clin J Oncol Nurs , vol.5 , pp. 15-18
    • Nirenberg, A.1
  • 8
    • 0028916174 scopus 로고
    • Stereospecific determination, chiral inversion in vitro and pharmacokinetics in humans of the enantiomers of thalidomide
    • Eriksson T, Bjorkman S, Roth B, Fyge A, Hoglund P. Stereospecific determination, chiral inversion in vitro and pharmacokinetics in humans of the enantiomers of thalidomide. Chirality 1995;7:44-52.
    • (1995) Chirality , vol.7 , pp. 44-52
    • Eriksson, T.1    Bjorkman, S.2    Roth, B.3    Fyge, A.4    Hoglund, P.5
  • 10
    • 0013809449 scopus 로고
    • The metabolism of thalidomide: The fate of thalidomide and some of its hydrolysis products in various species
    • Schumacher H, Smith RL, Williams RT. The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species. Br J Pharmacol 1965;25:338-51.
    • (1965) Br J Pharmacol , vol.25 , pp. 338-351
    • Schumacher, H.1    Smith, R.L.2    Williams, R.T.3
  • 14
  • 15
    • 0036134526 scopus 로고    scopus 로고
    • Thalidomide: An antineoplastic agent
    • Amato RJ. Thalidomide: An antineoplastic agent. Curr Oncol Rep 2002;4:56-62.
    • (2002) Curr Oncol Rep , vol.4 , pp. 56-62
    • Amato, R.J.1
  • 16
    • 0022253886 scopus 로고
    • Thalidomide induces imbalances in T-lymphocyte subpopulations in the circulating blood of healthy males
    • Gad SM, Shannon EJ, Krotoski WA, Hastings RC. Thalidomide induces imbalances in T-lymphocyte subpopulations in the circulating blood of healthy males. Lepr Rev 1985;56:35-39.
    • (1985) Lepr Rev , vol.56 , pp. 35-39
    • Gad, S.M.1    Shannon, E.J.2    Krotoski, W.A.3    Hastings, R.C.4
  • 17
    • 0032100486 scopus 로고    scopus 로고
    • Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset
    • Haslett PA, Corral LG, Albert M, Kaplan G. Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset. J Exp Med 1998;187:1885-92.
    • (1998) J Exp Med , vol.187 , pp. 1885-1892
    • Haslett, P.A.1    Corral, L.G.2    Albert, M.3    Kaplan, G.4
  • 18
    • 0028928143 scopus 로고
    • The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures
    • McHugh SM, Rifkin IR, Deighton J, Wilson AB, Lachmann PJ, Lockwood CM, et al. The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures. Clin Exp Immunol 1995;99:160-7.
    • (1995) Clin Exp Immunol , vol.99 , pp. 160-167
    • McHugh, S.M.1    Rifkin, I.R.2    Deighton, J.3    Wilson, A.B.4    Lachmann, P.J.5    Lockwood, C.M.6
  • 19
    • 0025724048 scopus 로고
    • Immunosuppressive properties of thalidomide. Inhibition of in vitro lymphocyte proliferation alone and in combination with cyclosporine or FK506
    • Keenan RJ, Eiras G, Burckart GJ, Stuart RS, Hardesty RL, Vogelsang G, et al. Immunosuppressive properties of thalidomide. Inhibition of in vitro lymphocyte proliferation alone and in combination with cyclosporine or FK506. Transplantation 1991;52:908-10.
    • (1991) Transplantation , vol.52 , pp. 908-910
    • Keenan, R.J.1    Eiras, G.2    Burckart, G.J.3    Stuart, R.S.4    Hardesty, R.L.5    Vogelsang, G.6
  • 20
    • 0034508512 scopus 로고    scopus 로고
    • Current role of thalidomide in cancer treatment
    • Thomas DA, Kantarjian HM. Current role of thalidomide in cancer treatment. Curr Opin Oncol 2000;12:564-73.
    • (2000) Curr Opin Oncol , vol.12 , pp. 564-573
    • Thomas, D.A.1    Kantarjian, H.M.2
  • 21
    • 0028365244 scopus 로고
    • Thalidomide and the immune system. 3. Simultaneous up- and down-regulation of different integrin receptors on human white blood cells
    • Nogueira AC, Neubert R, Helge H, Neubert D. Thalidomide and the immune system. 3. Simultaneous up- and down-regulation of different integrin receptors on human white blood cells. Life Sci 1994;55:77-92.
    • (1994) Life Sci , vol.55 , pp. 77-92
    • Nogueira, A.C.1    Neubert, R.2    Helge, H.3    Neubert, D.4
  • 22
    • 0030701896 scopus 로고    scopus 로고
    • Effects of thalidomide on neutrophil respiratory burst, chemotaxis, and transmigration of cytokine- and endotoxin-activated endothelium
    • Dunzendorfer S, Schratzberger P, Reinisch N, Kahler CM, Wiedermann CJ. Effects of thalidomide on neutrophil respiratory burst, chemotaxis, and transmigration of cytokine- and endotoxin-activated endothelium. Naunyn Schmiedebergs Arch Pharmacol 1997;356:529-35.
    • (1997) Naunyn Schmiedebergs Arch Pharmacol , vol.356 , pp. 529-535
    • Dunzendorfer, S.1    Schratzberger, P.2    Reinisch, N.3    Kahler, C.M.4    Wiedermann, C.J.5
  • 25
    • 0026080801 scopus 로고
    • Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes
    • Sampaio EP, Sarno EN, Galilly R, Cohn ZA, Kaplan G. Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med 1991;173:699-703.
    • (1991) J Exp Med , vol.173 , pp. 699-703
    • Sampaio, E.P.1    Sarno, E.N.2    Galilly, R.3    Cohn, Z.A.4    Kaplan, G.5
  • 26
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • Moreira AL, Sampaio EP, Zmuidzinas A, Frindt P, Smith KA, Kaplan G. Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med 1993;177:1675-80.
    • (1993) J Exp Med , vol.177 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3    Frindt, P.4    Smith, K.A.5    Kaplan, G.6
  • 27
    • 0029664920 scopus 로고    scopus 로고
    • Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibitory action on tumor necrosis factor production
    • Turk BE, Jiang H, Liu JO. Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibitory action on tumor necrosis factor production. Proc Natl Acad Sci USA 1996;93:7552-7556.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7552-7556
    • Turk, B.E.1    Jiang, H.2    Liu, J.O.3
  • 28
    • 0035933772 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity
    • Keifer JA, Guttridge DC, Ashburner BP, Baldwin AS. Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity. J Biol Chem 2001;276:22382-7.
    • (2001) J Biol Chem , vol.276 , pp. 22382-22387
    • Keifer, J.A.1    Guttridge, D.C.2    Ashburner, B.P.3    Baldwin, A.S.4
  • 29
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB
    • Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB. J Clin Invest 2001;3, 107:241-246.
    • (2001) J Clin Invest , vol.107 , Issue.3 , pp. 241-246
    • Baldwin, A.S.1
  • 32
    • 73849154636 scopus 로고
    • The saga of thalidomide (concluded): Neuropathy to embryopathy with case reports of congenital anomalies
    • Mellin GW, Katzenstein M. The saga of thalidomide (concluded): Neuropathy to embryopathy with case reports of congenital anomalies. N Engl J Med 1962;267:1238-1244.
    • (1962) N Engl J Med , vol.267 , pp. 1238-1244
    • Mellin, G.W.1    Katzenstein, M.2
  • 35
    • 0035469858 scopus 로고    scopus 로고
    • Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy
    • Zangari M, Anaissie E, Barlogie B, Badros A, Desikan R, Gopal V, et al. Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy. Blood 2001;98:1614-1615.
    • (2001) Blood , vol.98 , pp. 1614-1615
    • Zangari, M.1    Anaissie, E.2    Barlogie, B.3    Badros, A.4    Desikan, R.5    Gopal, V.6
  • 36
    • 0034795178 scopus 로고    scopus 로고
    • A randomized phase II trial of docetaxel (Taxotere) plus thalidomide in androgen-independent prostate cancer
    • Figg WD, Arlen P, Gulley J, Fernandez P, Noone M, Fedenko K, et al. A randomized phase II trial of docetaxel (Taxotere) plus thalidomide in androgen-independent prostate cancer. Seminars in Oncology 2001;28(4 Suppl 15):62-66.
    • (2001) Seminars in Oncology , vol.28 , Issue.4 SUPPL. 15 , pp. 62-66
    • Figg, W.D.1    Arlen, P.2    Gulley, J.3    Fernandez, P.4    Noone, M.5    Fedenko, K.6
  • 37
    • 0033857366 scopus 로고    scopus 로고
    • Potential novel uses of thalidomide. Focus on palliative care
    • Peuckmann V, Fisch M, Bruera E. Potential novel uses of thalidomide. Focus on palliative care. Drugs 2000;60:273-292.
    • (2000) Drugs , vol.60 , pp. 273-292
    • Peuckmann, V.1    Fisch, M.2    Bruera, E.3
  • 40
    • 84883833410 scopus 로고
    • Thalidomide in the treatment of lepra reactions
    • Sheskin J. Thalidomide in the treatment of lepra reactions. J Clin Pharmacol 1965;6:303-6.
    • (1965) J Clin Pharmacol , vol.6 , pp. 303-306
    • Sheskin, J.1
  • 41
    • 0014823723 scopus 로고
    • Thalidomide in the treatment of erythema nodosum leprosum. With a note on selected laboratory abnormalities in erythema nodosum leprosum
    • Hastings RC, Trautman JR, Enna CD, Jacobson RR. Thalidomide in the treatment of erythema nodosum leprosum. With a note on selected laboratory abnormalities in erythema nodosum leprosum. Clin Pharmacol Ther 1970;11:481-7.
    • (1970) Clin Pharmacol Ther , vol.11 , pp. 481-487
    • Hastings, R.C.1    Trautman, J.R.2    Enna, C.D.3    Jacobson, R.R.4
  • 42
    • 0014504028 scopus 로고
    • Treatment of moderately severe erythema nodosum leprosum with thalidomide - A double-blind controlled trial
    • Pearson JM, Vedagiri M. Treatment of moderately severe erythema nodosum leprosum with thalidomide-a double-blind controlled trial. Lepr Rev 1969;40:111-6.
    • (1969) Lepr Rev , vol.40 , pp. 111-116
    • Pearson, J.M.1    Vedagiri, M.2
  • 43
    • 0015029994 scopus 로고
    • An internally-controlled double blind trial of thalidomide in severe erythema nodosum leprosum
    • Waters MF. An internally-controlled double blind trial of thalidomide in severe erythema nodosum leprosum. Lepr Rev 1971;42:26-42.
    • (1971) Lepr Rev , vol.42 , pp. 26-42
    • Waters, M.F.1
  • 46
    • 0032520803 scopus 로고    scopus 로고
    • Thalidomide in the treatment of the mucocutaneous lesions of the Behcet syndrome. A randomized, double-blind, placebo-controlled trial
    • Hamuryudan V, Mat C, Saip S, Ozyazgan Y, Siva A, Yurdakul S, et al. Thalidomide in the treatment of the mucocutaneous lesions of the Behcet syndrome. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1998;128:443-50.
    • (1998) Ann Intern Med , vol.128 , pp. 443-450
    • Hamuryudan, V.1    Mat, C.2    Saip, S.3    Ozyazgan, Y.4    Siva, A.5    Yurdakul, S.6
  • 47
    • 0032714591 scopus 로고    scopus 로고
    • Thalidomide therapy for patients with refractory Crohn's disease: An open-label trial
    • Ehrenpreis ED, Kane SV, Cohen LB, Cohen RD, Hanauer SB. Thalidomide therapy for patients with refractory Crohn's disease: an open-label trial. Gastroenterology 1999;117:1271-7.
    • (1999) Gastroenterology , vol.117 , pp. 1271-1277
    • Ehrenpreis, E.D.1    Kane, S.V.2    Cohen, L.B.3    Cohen, R.D.4    Hanauer, S.B.5
  • 48
    • 0031583764 scopus 로고    scopus 로고
    • Thalidomide in Crohn's disease
    • Wettstein AR, Meagher AP. Thalidomide in Crohn's disease. Lancet 1997;350:1445-6.
    • (1997) Lancet , vol.350 , pp. 1445-1446
    • Wettstein, A.R.1    Meagher, A.P.2
  • 56
    • 0033379285 scopus 로고    scopus 로고
    • New uses for old drugs in HIV infection: The role of hydroxyurea, cyclosporin and thalidomide
    • Ravot E, Lisziewicz J, Lori F. New uses for old drugs in HIV infection: the role of hydroxyurea, cyclosporin and thalidomide. Drugs 1999;58:953-63.
    • (1999) Drugs , vol.58 , pp. 953-963
    • Ravot, E.1    Lisziewicz, J.2    Lori, F.3
  • 57
    • 8244247121 scopus 로고    scopus 로고
    • Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection
    • National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group
    • Jacobson JM, Greenspan JS, Spritzler J, Ketter N, Fahey JL, Jackson JB, et al. Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group. N Engl J Med 1997;336:1487-93.
    • (1997) N Engl J Med , vol.336 , pp. 1487-1493
    • Jacobson, J.M.1    Greenspan, J.S.2    Spritzler, J.3    Ketter, N.4    Fahey, J.L.5    Jackson, J.B.6
  • 58
    • 0032175106 scopus 로고    scopus 로고
    • Long-term thalidomide use in refractory cutaneous lesions of systemic lupus erythematosus
    • Sato EI, Assis LS, Lourenzi VP, Andrade LE. Long-term thalidomide use in refractory cutaneous lesions of systemic lupus erythematosus. Rev Assoc Med Bras 1998;44:289-93.
    • (1998) Rev Assoc Med Bras , vol.44 , pp. 289-293
    • Sato, E.I.1    Assis, L.S.2    Lourenzi, V.P.3    Andrade, L.E.4
  • 59
    • 0034072592 scopus 로고    scopus 로고
    • Clinical and immunologic parameters during thalidomide treatment of lupus erythematosus
    • Walchner M, Meurer M, Plewig G, Messer G. Clinical and immunologic parameters during thalidomide treatment of lupus erythematosus. Int J Dermatol 2000;39:383-8.
    • (2000) Int J Dermatol , vol.39 , pp. 383-388
    • Walchner, M.1    Meurer, M.2    Plewig, G.3    Messer, G.4
  • 60
    • 0034618962 scopus 로고    scopus 로고
    • Subacute cutaneous lupus. Evolutive and therapeutic features of a series of 24 cases
    • Versapuech J, Beylot-Barry M, Doutre MS, Beylot C. Subacute cutaneous lupus. Evolutive and therapeutic features of a series of 24 cases. Presse Med 2000;29:1596-9.
    • (2000) Presse Med , vol.29 , pp. 1596-1599
    • Versapuech, J.1    Beylot-Barry, M.2    Doutre, M.S.3    Beylot, C.4
  • 61
    • 0032864026 scopus 로고    scopus 로고
    • American experience with low-dose thalidomide therapy for severe cutaneous lupus erythematosus
    • Duong DJ, Spigel GT, Moxley RT 3rd, Gaspari AA. American experience with low-dose thalidomide therapy for severe cutaneous lupus erythematosus. Arch Dermatol 1999;135:1079-87.
    • (1999) Arch Dermatol , vol.135 , pp. 1079-1087
    • Duong, D.J.1    Spigel, G.T.2    Moxley R.T. III3    Gaspari, A.A.4
  • 63
    • 0023629987 scopus 로고
    • Histiocytose X avec "granuloma eosinophile vulvaire". Effect spectaculaire de la thalidomide
    • Gnassia AM, Gnassia T, Bonvalet D, Puissant A, Goudal H. Histiocytose X avec "granuloma eosinophile vulvaire". Effect spectaculaire de la thalidomide. Ann Dermatol Venerol 1987;114:1387-1389.
    • (1987) Ann Dermatol Venerol , vol.114 , pp. 1387-1389
    • Gnassia, A.M.1    Gnassia, T.2    Bonvalet, D.3    Puissant, A.4    Goudal, H.5
  • 65
    • 0033785490 scopus 로고    scopus 로고
    • A review of angiogenesis and anti-angiogeneric therapy with thalidomide in multiple myeloma
    • Rajkumar SV, Witzi RE. A review of angiogenesis and anti-angiogeneric therapy with thalidomide in multiple myeloma. Cancer Treat Rev 2000;26:351-362.
    • (2000) Cancer Treat Rev , vol.26 , pp. 351-362
    • Rajkumar, S.V.1    Witzi, R.E.2
  • 67
    • 0034116457 scopus 로고    scopus 로고
    • Frequent good partial remissions from thalidomide including best response ever in patients with advanced refractory and relapsed myeloma
    • Juliusson G, Celsing F, Turesson I, Lenhoff S, Adriansson M, Malm C. Frequent good partial remissions from thalidomide including best response ever in patients with advanced refractory and relapsed myeloma. Br J Hematol 2000;109:89-96.
    • (2000) Br J Hematol , vol.109 , pp. 89-96
    • Juliusson, G.1    Celsing, F.2    Turesson, I.3    Lenhoff, S.4    Adriansson, M.5    Malm, C.6
  • 68
    • 0035880229 scopus 로고    scopus 로고
    • Extended survival in advanced and refractory muliple myeloma after single agent thalidomide: Identification of prognostic factors in a phase 2 study of 169 patients
    • Barologie B, Desikan R, Eddlemon P, Spencer T, Zeldis J, Munshi N, et al. Extended survival in advanced and refractory muliple myeloma after single agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients. Blood 2001;98:492-4.
    • (2001) Blood , vol.98 , pp. 492-494
    • Barologie, B.1    Desikan, R.2    Eddlemon, P.3    Spencer, T.4    Zeldis, J.5    Munshi, N.6
  • 70
    • 0037103198 scopus 로고    scopus 로고
    • Efficacy of a low dose of thalidomide in advanced multiple myeloma
    • Leleu X, Magro L, Fawaz A, Bauters F, Facon T, Yakoub-Agha I. Efficacy of a low dose of thalidomide in advanced multiple myeloma. Blood 2002;100:1519-20.
    • (2002) Blood , vol.100 , pp. 1519-1520
    • Leleu, X.1    Magro, L.2    Fawaz, A.3    Bauters, F.4    Facon, T.5    Yakoub-Agha, I.6
  • 71
    • 0034995376 scopus 로고    scopus 로고
    • Thalidomide in multiple myeloma: Lack of response of soft-tissue plasmacytomas
    • Blade J, Perales M, Rosinol L, Tuset M, Montoto S, Esteve J, et al. Thalidomide in multiple myeloma: lack of response of soft-tissue plasmacytomas. Br J Hematol 2001;113:422-424.
    • (2001) Br J Hematol , vol.113 , pp. 422-424
    • Blade, J.1    Perales, M.2    Rosinol, L.3    Tuset, M.4    Montoto, S.5    Esteve, J.6
  • 72
    • 0034861712 scopus 로고    scopus 로고
    • Extramedullary progression despite a good response in the bone marrow in patients treated with thalidomide for multiple myeloma
    • Avigdor A, Raani P, Levi I, Hardan I, Ben-Bassat I. Extramedullary progression despite a good response in the bone marrow in patients treated with thalidomide for multiple myeloma. Leuk Lymphoma 2001;42:683-687.
    • (2001) Leuk Lymphoma , vol.42 , pp. 683-687
    • Avigdor, A.1    Raani, P.2    Levi, I.3    Hardan, I.4    Ben-Bassat, I.5
  • 73
    • 85112397103 scopus 로고    scopus 로고
    • A phase II trial of thalidomide in the treatment of relapsed multiple myeloma (MM) with laboratory correlative studies
    • Abstract 723
    • Rajkumar SV, Fonseca R, Dispensieri A, et al. A phase II trial of thalidomide in the treatment of relapsed multiple myeloma (MM) with laboratory correlative studies. Blood 2000;96:168a, Abstract 723.
    • (2000) Blood , vol.96
    • Rajkumar, S.V.1    Fonseca, R.2    Dispensieri, A.3
  • 74
    • 0035412366 scopus 로고    scopus 로고
    • Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
    • Davies FE, Raje N, Hideshima T, Lentzsch S, Young G, Tai YT, et al. Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma. Blood 2001;98:210-216.
    • (2001) Blood , vol.98 , pp. 210-216
    • Davies, F.E.1    Raje, N.2    Hideshima, T.3    Lentzsch, S.4    Young, G.5    Tai, Y.T.6
  • 75
    • 0035927983 scopus 로고    scopus 로고
    • Deep vein thrombosis and thalidomide therapy for multiple myeloma
    • Osman K, Comenzo R, Rajkumar SF. Deep vein thrombosis and thalidomide therapy for multiple myeloma. N Engl J Med 2001;344:1951-1952.
    • (2001) N Engl J Med , vol.344 , pp. 1951-1952
    • Osman, K.1    Comenzo, R.2    Rajkumar, S.F.3
  • 77
    • 0035992291 scopus 로고    scopus 로고
    • Thalidomide paradoxical effect on concomitant multiple myeloma and myelodysplasia
    • Badros A, Morris C, Zangari M, Barlogie B, Tricot G. Thalidomide paradoxical effect on concomitant multiple myeloma and myelodysplasia. Leuk Lymphoma 2002;43:1267-1271.
    • (2002) Leuk Lymphoma , vol.43 , pp. 1267-1271
    • Badros, A.1    Morris, C.2    Zangari, M.3    Barlogie, B.4    Tricot, G.5
  • 78
    • 0036464605 scopus 로고    scopus 로고
    • Efficacy and safety of thalidomide in patients with acute myeloid leukaemia
    • Steins MB, Padro T, Bieker R, Ruiz S, Kropff M, Kienast J, et al. Efficacy and safety of thalidomide in patients with acute myeloid leukaemia. Blood 2002;99:834-839.
    • (2002) Blood , vol.99 , pp. 834-839
    • Steins, M.B.1    Padro, T.2    Bieker, R.3    Ruiz, S.4    Kropff, M.5    Kienast, J.6
  • 79
    • 0033954292 scopus 로고    scopus 로고
    • Phase II trial of antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
    • Fine HA, Figg WD, Jaeckle K, Wen PY, Kyritsis AP, Loeffler JS, et al. Phase II trial of antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. J Clin Oncol 2000;18:708-715.
    • (2000) J Clin Oncol , vol.18 , pp. 708-715
    • Fine, H.A.1    Figg, W.D.2    Jaeckle, K.3    Wen, P.Y.4    Kyritsis, A.P.5    Loeffler, J.S.6
  • 80
    • 0035191268 scopus 로고    scopus 로고
    • Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme
    • Marx GM, Pavlakis N, McCowatt S, Boyle FM, Levi JA, Bell DR, et al. Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme. Neurooncol 2001;54:31-8.
    • (2001) Neurooncol , vol.54 , pp. 31-38
    • Marx, G.M.1    Pavlakis, N.2    McCowatt, S.3    Boyle, F.M.4    Levi, J.A.5    Bell, D.R.6
  • 81
    • 0347289617 scopus 로고    scopus 로고
    • Phase II study of thalidomide as an anti-angiogenic agent in the treatment of recurrent glioblastoma multiforme
    • Abstract 613
    • Bell D, Biggs M, Boyle F, Cook R, Freilich R, Levi J, et al. Phase II study of thalidomide as an anti-angiogenic agent in the treatment of recurrent glioblastoma multiforme. Proc Am Soc Clin Oncol 2000;Abstract 613.
    • (2000) Proc Am Soc Clin Oncol
    • Bell, D.1    Biggs, M.2    Boyle, F.3    Cook, R.4    Freilich, R.5    Levi, J.6
  • 83
    • 0031675320 scopus 로고    scopus 로고
    • Activity of thalidomide in AIDS related Kaposi's sarcoma and correlation with HHV8 titre
    • Fife K, Howard MR, Gracie F, Phillips RH, Bower M. Activity of thalidomide in AIDS related Kaposi's sarcoma and correlation with HHV8 titre. Int J STD AIDS 1998;9:751-55.
    • (1998) Int J STD AIDS , vol.9 , pp. 751-755
    • Fife, K.1    Howard, M.R.2    Gracie, F.3    Phillips, R.H.4    Bower, M.5
  • 86
    • 0033980850 scopus 로고    scopus 로고
    • Continuous low dose Thalidomide: A phase II study in advanced melanoma, renal cell, ovarian and breast cancer
    • Eisen T, Boshoff C, Mak I, Sapunar F, Vaughan MM, Pyle L, et al. Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer. Brit J Cancer 2000;82, 4:812-17.
    • (2000) Brit J Cancer , vol.82 , Issue.4 , pp. 812-817
    • Eisen, T.1    Boshoff, C.2    Mak, I.3    Sapunar, F.4    Vaughan, M.M.5    Pyle, L.6
  • 87
    • 0036139999 scopus 로고    scopus 로고
    • Phase II trial of thalidomide for patients with advanced renal cell carcinoma
    • Motzer RJ, Berg W, Ginsberg M, Russo P, Vuky J, Yu R, et al. Phase II trial of thalidomide for patients with advanced renal cell carcinoma. J Clin Oncol 2002;1:302-6.
    • (2002) J Clin Oncol , vol.1 , pp. 302-306
    • Motzer, R.J.1    Berg, W.2    Ginsberg, M.3    Russo, P.4    Vuky, J.5    Yu, R.6
  • 88
    • 17944362585 scopus 로고    scopus 로고
    • The treatment of advanced renal cell cancer with high-dose oral thalidomide
    • Stebbing J, Benson C, Eisen T, Pyle L, Smalley K, Bridle H, et al. The treatment of advanced renal cell cancer with high-dose oral thalidomide. Br J Cancer 2001;85:953-8.
    • (2001) Br J Cancer , vol.85 , pp. 953-958
    • Stebbing, J.1    Benson, C.2    Eisen, T.3    Pyle, L.4    Smalley, K.5    Bridle, H.6
  • 90
    • 0034783270 scopus 로고    scopus 로고
    • A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer
    • Figg WD, Dahut W, Duray P, Hamilton M, Tompkins A, Steinberg SM, et al. A randomized phase II trial of thalidomide, an angiogenesis inhibitor, in patients with androgen-independent prostate cancer. Clin Cancer Res 2001;7:1888-93.
    • (2001) Clin Cancer Res , vol.7 , pp. 1888-1893
    • Figg, W.D.1    Dahut, W.2    Duray, P.3    Hamilton, M.4    Tompkins, A.5    Steinberg, S.M.6
  • 91
    • 0032983205 scopus 로고    scopus 로고
    • Thalidomide upregulates prostate-specific antigen secretion from LNCaP cells
    • Dixon SC, Kruger EA, Bauer KS, Wigg WD. Thalidomide upregulates prostate-specific antigen secretion from LNCaP cells. Cancer Chemother Pharmacol 1999;43 (Suppl):78-84.
    • (1999) Cancer Chemother Pharmacol , vol.43 , Issue.SUPPL. , pp. 78-84
    • Dixon, S.C.1    Kruger, E.A.2    Bauer, K.S.3    Wigg, W.D.4
  • 93
    • 0036605798 scopus 로고    scopus 로고
    • Temozolomide plus thalidomide in patients with advanced melanoma: Results of a dose-finding trial
    • Hwu WJ, Krown SE, Panageas K, Menell JH, Chapman PB, Livingston PO, et al. Temozolomide plus thalidomide in patients with advanced melanoma: results of a dose-finding trial. J Clin Oncol 2002;11:2607-9.
    • (2002) J Clin Oncol , vol.11 , pp. 2607-2609
    • Hwu, W.J.1    Krown, S.E.2    Panageas, K.3    Menell, J.H.4    Chapman, P.B.5    Livingston, P.O.6
  • 95
    • 0001182991 scopus 로고    scopus 로고
    • Phase II study of thalidomide in patients (pts) with unresectable hepatocellular carcinoma (HCC)
    • Abstract 2002. 38 th Annual Meeting, May 18-21 2002, Orlando FL
    • Lin AY, Brophy N, Fisher GA, So S, Biggs C, Yock T, et al. Phase II study of thalidomide in patients (pts) with unresectable hepatocellular carcinoma (HCC). Proc Am Soc Clin Oncol 2002;21, 2:p 97b, Abstract 2002, 38th Annual Meeting, May 18-21 2002, Orlando FL.
    • (2002) Proc Am Soc Clin Oncol , vol.21 , Issue.2
    • Lin, A.Y.1    Brophy, N.2    Fisher, G.A.3    So, S.4    Biggs, C.5    Yock, T.6
  • 96
    • 23544478499 scopus 로고    scopus 로고
    • A phase II study of thalidomide in metastatic neuroendocrine tumors
    • Abstract 1931. 38th Annual Meeting, May 18-21 2002, Orlando FL
    • Xu Y, Ellison C, Martin E, Young D, Campbell J, Vinci L, et al. A phase II study of thalidomide in metastatic neuroendocrine tumors. Proc Am Soc Clin Oncol 2002;21, 2:p 30b, Abstract 1931, 38th Annual Meeting, May 18-21 2002, Orlando FL.
    • (2002) Proc Am Soc Clin Oncol , vol.21 , Issue.2
    • Xu, Y.1    Ellison, C.2    Martin, E.3    Young, D.4    Campbell, J.5    Vinci, L.6
  • 97
    • 4244016782 scopus 로고    scopus 로고
    • Thalidomide alone and in combination with cisplatin/gemcitabine chemotherapy for malignant mesothelioma (MM): Preliminary results from two phase II studies
    • Abstract 1885. 38th Annual Meeting, May 18-21 2002, Orlando FL
    • Pavlakis N, Williams G, Harvey R, Aslani A, Abraham R, Wheeler H. Thalidomide alone and in combination with cisplatin/gemcitabine chemotherapy for malignant mesothelioma (MM): preliminary results from two phase II studies. Proc Am Soc Clin Oncol 2002;21, 2:p19b, Abstract 1885 38th Annual Meeting, May 18-21 2002, Orlando FL.
    • (2002) Proc Am Soc Clin Oncol , vol.21 , Issue.2
    • Pavlakis, N.1    Williams, G.2    Harvey, R.3    Aslani, A.4    Abraham, R.5    Wheeler, H.6
  • 98
    • 0347919853 scopus 로고    scopus 로고
    • Thalidomide for treatment of mesothelioma
    • Howe M. Thalidomide for treatment of mesothelioma. Lancet Oncol 2001;2:253.
    • (2001) Lancet Oncol , vol.2 , pp. 253
    • Howe, M.1
  • 100
    • 0034568351 scopus 로고    scopus 로고
    • Irinotecan and thalidomide in metastatic colorectal cancer
    • Govindarajan R. Irinotecan and thalidomide in metastatic colorectal cancer. Oncology (Huntingt)2000;14:29-32.
    • (2000) Oncology (Huntingt) , vol.14 , pp. 29-32
    • Govindarajan, R.1
  • 102
    • 0035498677 scopus 로고    scopus 로고
    • Phase II study of the antiangiogenesis agent thalidomide in recurrent or metastatic squamous cell carcinoma of the head and neck
    • Tseng JE, Glisson BS, Khuri FR, Shin DM, Myers JN, ElNaggar AK, et al. Phase II study of the antiangiogenesis agent thalidomide in recurrent or metastatic squamous cell carcinoma of the head and neck. Cancer 2001;92:2364-73.
    • (2001) Cancer , vol.92 , pp. 2364-2373
    • Tseng, J.E.1    Glisson, B.S.2    Khuri, F.R.3    Shin, D.M.4    Myers, J.N.5    ElNaggar, A.K.6
  • 103
    • 0346028185 scopus 로고    scopus 로고
    • Pilot and safety trial of carboplatin, paclitaxel and thalidomide in advanced non-small cell lung cancer
    • Abstract 2130
    • Brophy D, Hammes L, Kim KM, Larson M, Mehta M, Merchant J, et al. Pilot and safety trial of carboplatin, paclitaxel and thalidomide in advanced non-small cell lung cancer. J Clin Oncol 2000:Abstract 2130.
    • (2000) J Clin Oncol
    • Brophy, D.1    Hammes, L.2    Kim, K.M.3    Larson, M.4    Mehta, M.5    Merchant, J.6
  • 104
    • 4243576128 scopus 로고    scopus 로고
    • Phase II trial of Thalidomide in unresectable hepatocellular carcinoma (HCC) - A cancer therapeutics group (CTRG) study
    • Abstract 2282. 37th Annual meeting, May 12-15 2001, San Francisco CA
    • Boyer MJ, Lim R, Clarke S, Milward J, Wong E. Phase II trial of Thalidomide in unresectable hepatocellular carcinoma (HCC) - a cancer therapeutics group (CTRG) study. Proc Am Soc Clin Oncol 2001;20, 2:p 133b, Abstract 2282, 37th Annual meeting, May 12-15 2001, San Francisco CA.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.2
    • Boyer, M.J.1    Lim, R.2    Clarke, S.3    Milward, J.4    Wong, E.5


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