Synthesis of novel 3-oxa-chromanol type antioxidants

Tetrahedron

Volumn 59, Issue 15, 2003, Pages 2687-2691

  Adelwöhrer, Christian ^a   Rosenau, Thomas ^a   Gille, Lars ^b   Kosma, Paul ^a  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^b UNIVERSITY OF VETERINARY MEDICINE   (Austria)

Author keywords

3 oxa chromanol; Trimethylhydroquinone; Vitamin E

Indexed keywords

2,4 BIS(4 NITROPHENYL) 5,7,8 TRIMETHYL 4H BENZO[1,3]DIOXIN 6 OL; 2,4 DICYCLOHEXYL 5,7,8 TRIMETHYL 4H 1,3 BENZODIOXIN 6 OL; 2,4 DIETHYL 5,7,8 TRIMETHYL 4H 1,3 BENZODIOXIN 6 OL; 2,4 DIISOPROPYL 5,7,8 TRIMETHYL 4H BENZO[1,3]DIOXIN 6 OL; 2,4 DIPROPYL 5,7,8 TRIMETHYL 4H BENZO[1,3]DIOXIN 6 OL; 2,4,5,7,8 PENTAMETHYL 4H 1,3 BENZODIOXIN 6 OL; 5,7,8 TRIMETHYL 2,4 DIPHENYL 4H 1,3 BENZODIOXIN 6 OL; ALDEHYDE; ALPHA TOCOPHEROL DERIVATIVE; ANTIOXIDANT; HYDROQUINONE DERIVATIVE; TRIMETHYLHYDROQUINONE; UNCLASSIFIED DRUG;

ARTICLE; DIASTEREOISOMER; DRUG SYNTHESIS; POLYMERIZATION; PRIORITY JOURNAL; SUBSTITUTION REACTION;

EID: 0037424847     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00287-4     Document Type: Article

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12. Preparation and properties of the basis compound without substituents in the dioxinol moiety will be reported elsewhere. This compound is not accessible by condensation with formaldehyde (formaline) according to the general procedure, which in this case leads to complex mixtures containing 1,3,4,5,6,8-hexamethyl-9H-xanthene-2,7-diol as the only identifiyable compound.
13. trans=exp (-Δ(ΔE)/RT).
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17. 3)/a(2-CH)=3.89), as follows from the McConnell equation.
18. 3)=0.97 G, a(4-CH)=2.46 G, a(2-CH)=1.57 G (g=2.008218).