Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding

Journal of Biological Chemistry

Volumn 278, Issue 10, 2003, Pages 8429-8434

  Karpowich, Nathan K ^b   Huang, Hector H ^b   Smith, Paul C ^b   Hunt, John F ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; CRYSTAL STRUCTURE; ESCHERICHIA COLI; VITAMINS;

TRANSMEMBRANE PUMPS;

PROTEINS;

CYANOCOBALAMIN; CYANOCOBALAMIN BINDING PROTEIN; PROTEIN BTUF; UNCLASSIFIED DRUG; BTUF PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; LIGAND; PERIPLASMIC BINDING PROTEIN;

ALPHA HELIX; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ESCHERICHIA COLI; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; SURFACE PROPERTY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANIMALIA; ESCHERICHIA COLI;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI PROTEINS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PERIPLASMIC BINDING PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; VITAMIN B 12;

EID: 0037424465     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212239200     Document Type: Article

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