Purification of a trypsin-stable lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activity

Biochemical and Biophysical Research Communications

Volumn 301, Issue 2, 2003, Pages 545-550

  Wong, Jack H ^a   Ng, T B ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

GALACTURONIC ACID; LECTIN; MONOSACCHARIDE; PHYTOHEMAGGLUTININ; POLYGALACTURONIC ACID; POTASSIUM ION; RNA DIRECTED DNA POLYMERASE; TRYPSIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BEAN; CHROMATOGRAPHY; CONTROLLED STUDY; ENZYME ACTIVITY; FAST PROTEIN LIQUID CHROMATOGRAPHY; HEMAGGLUTINATION; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; ION EXCHANGE; LEUKEMIA; LEUKEMIA CELL; LIVER CELL CARCINOMA; MITOGENESIS; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; SEQUENCE HOMOLOGY; SPLEEN CELL;

HUMAN IMMUNODEFICIENCY VIRUS 1; MURINAE; PHASEOLUS; PHASEOLUS (ANGIOSPERM); VIGNA; VIGNA SESQUIPEDALIS; VIGNA SUBTERRANEA; VIGNA UNGUICULATA SUBSP. SESQUIPEDALIS;

EID: 0037423690     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)03080-2     Document Type: Article

References (22)

1. Wang H.X., Ng T.B., Liu W.K., Ooi V.E.C., Chang S.T. Isolation and characterization of two distinct lectins with antiproliferative activity from the cultured mycelium of the edible mushroom Tricholoma mongolicum. Int. J. Pept. Protein Res. 46:1995;508-513.
2. Yu L.G., Milton J.D., Fernig D.G. Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friendenreich antigen-binding lectins. J. Cell Physiol. 186:2001;282-287.
3. Wang H.X., Gao J., Ng T.B. A new lectin with highly potent antihepatoma Pleurotus ostreatus. Biochem. Biophys. Res. Commun. 275:2000;810-816.
4. Wang H.X., Ng T.B., Liu Q.H. Isolation of a new heterodimeric lectin with mitogenic activity from fruiting bodies of the mushroom Agrocybe cylindracea. Life Sci. 70:2002;877-885.
5. She Q.B., Ng T.B., Liu W.K. A novel lectin with potent immunomodulatory activity isolated from both fruiting bodies and cultured mycelia of the edible mushroom Volvariella volvacea. Biochem. Biophys. Res. Commun. 247:1998;106-111.
6. Liopraga J., Gozia O., Tudor R., Brezuica L., Doyle R.J. Fusarium sp. Growth inhibition by wheat germ agglutinin. Biochim. Biophys. Acta. 1428:1999;424-432.
7. Ye X.Y., Ng T.B., Tsang P.W., Wang J. Isolation of a homodimeric lectin with antifungal and antiviral activities from red kidney bean (Phaseolus vulgaris) seeds. J. Protein Chem. 20:2001;367-375.
8. Ooi L.S., Ng T.B., Geng Y., Ooi V.E. Lectins from bulbs of the Chinese daffodil Narcissus tazetta (family Amaryllidaceae). Biochem. Cell Biol. 78:2000;463-468.
9. Wang H.X., Ng T.B. Examination of lectins, polysaccharopeptide, alkaloid, coumarin and trypsin inhibitor for inhibitory activity toward immunodeficiency virus reverse transcriptase and glycohydrolases. Planta Med. 67:2001;669-672.
10. Agrawal B.B., Goldstein I.J. Physical and chemical characterization of concanavalin A, the hemagglutinin from jack bean (Canavalia ensiformis). Biochim. Biophys. Acta. 33:1967;376-379.
11. Laemmli U.K., Favre M. Gel electrophoresis of proteins. J. Mol. Biol. 80:1973;575-599.
12. Wang H.X., Ng T.B. Isolation of cicadin, a novel and antifungal peptide from dried juvenile cicadas. Peptides. 23:2002;7-11.
13. Collins R.A., Ng T.B., Fong W.P., Wan C.C., Yeung H.W. A comparison of human immunodeficiency virus type 1 inhibition by partially purified aqueous extracts of Chinese medicinal herbs. Life Sci. 60:1997;PL 345-351.
14. Roberson B.J., Strength D.R. Characterization of a lectin from cowpeas. Prep. Biochem. 13:1983;45-56.
15. Van Damme E.J.M. Handbook of Plant Lectins: Properties and Biomedical Applications. 1998;Wiley, New York.
16. Ueda H., Saitoh T., Kojima K., Ogawa H. Multispecificity of a Psathyrella velutina mushroom lectin: heparin/pectin binding occurs at a site different from the N-acetylglucosamine N-acetylneuraminic acid-specific site. J. Biochem. (Tokyo). 126:1999;530-531.
17. Muller W.E., Zhan P.K., Kurelec B., Lucu C., Muller I., Uhlenbruck G. Lectin, a possible basis for symbiosis between bacteria and sponges. J. Bacteriol. 145:1981;548-558.
18. Woodle J.F. Lectin for gastrointestinal targeting - 15 years on. J. Drug Target. 7:2000;325-333.
19. Stobo J.D. Phytohemagglutinin and Con A: probes for murine "T" cell activation and differentiation. Transpl. Rev. 11:1972;60-86.
20. Wang H.X., Ng T.B., Ooi V.E.C., Liu W.K. Effects of lectins with different carbohydrate-binding specificities on hepatoma, choriocarcinoma, melanoma and osteosarcoma cell lines. Int. Biochem. Cell Biol. 32:2000;365-372.
21. Gozia O., Ciopraga J., Bentia T., Lunga M., Zanfirescu I., Tudor R., Roseanu A., Nitu F. Antifungal properties of lectin and new chitinase from potato tubers. FEBS Lett. 370:1993;245-249.
22. Broekaert W.F., Van Parijs J., Leyn F., Joos H., Peumans W. A chitin-binding lectin from stinging nettle rhizomes with antifungal properties. Science. 245:1998;1100-1102.