Simple liquid chromatographic method for the determination of physostigmine and its metabolite eseroline in rat plasma: Application to a pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 784, Issue 2, 2003, Pages 323-329

  Zhao, Bin ^a   Moochhala, Shabbir M ^a   Chaw, Cheng Shu ^a   Yang, Yi Yan ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Eseroline; Physostigmine

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES;

ANTICHOLINERGIC DRUG;

PHARMACOKINETICS;

ACETONITRILE; AMMONIA; ESEROLINE; METHANOL; N METHYLPHYSOSTIGMINE; PHYSOSTIGMINE; PHYSOSTIGMINE DERIVATIVE; SODIUM DERIVATIVE; SODIUM DIHYDROGENPHOSPHATE; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; EVAPORATION; FLOW RATE; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; RAT; RELIABILITY; SIGNAL NOISE RATIO; VALIDATION PROCESS;

ANIMALS; CHOLINESTERASE INHIBITORS; CHROMATOGRAPHY, LIQUID; INDOLES; MALE; PHYSOSTIGMINE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS;

EID: 0037419675     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(02)00817-6     Document Type: Article

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