Improved enantioselective assay for the determination of fluoxetine and norfluoxetine enantiomers in human plasma by liquid chromatography

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 784, Issue 2, 2003, Pages 375-383

  Gatti, Giuliana ^a   Bonomi, Ilaria ^a   Marchiselli, Roberto ^a   Fattore, Cinzia ^a   Spina, Edoardo ^b   Scordo, Gabriella ^b   Pacifici, Roberta ^c   Perucca, Emilio ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Enantiomer separation; Fluoxetine; Norfluoxetine

Indexed keywords

EXTRACTION; PHOSPHORIC ACID; ULTRAVIOLET DETECTORS;

ENANTIOMERS; THERAPUTIC DRUG MONITORING;

BIOASSAY;

2 PROPANOL; ACETONITRILE; FLUOROPHOSPHATE; FLUOXETINE; HEXANE; NORFLUOXETINE; PHOSPHORIC ACID DERIVATIVE; POTASSIUM HEXAFLUOROPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CHIRALITY; CONTROLLED STUDY; DRUG DETERMINATION; ENANTIOMER; ENANTIOSELECTIVITY; FILTERING OPERATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PLASMA; PRIORITY JOURNAL; STANDARD; ULTRAVIOLET RADIATION;

FLUOXETINE; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEROTONIN UPTAKE INHIBITORS; STEREOISOMERISM;

EID: 0037419669     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(02)00820-6     Document Type: Article

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