Dynorphin B is an agonist of nuclear opioid receptors coupling nuclear protein kinase C activation to the transcription of cardiogenic genes in GTR1 embryonic stem cells

Circulation Research

Volumn 92, Issue 6, 2003, Pages 623-629

  Ventura, Carlo ^a   Zinellu, Elisabetta ^b   Maninchedda, Emiliana ^b   Maioli, Margherita ^b  

^a UNIVERSITY OF SASSARI   (Italy)

^b NONE

Author keywords

Embryonic stem cells; Endorphins; Gene transcription; Nuclear receptors; Nuclear signaling

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; DYNORPHIN B; KAPPA OPIATE RECEPTOR; LIGAND; OPIATE ANTAGONIST; OPIATE RECEPTOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TRANSCRIPTION FACTOR GATA 4;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL NUCLEUS; CONFOCAL MICROSCOPY; CULTURE MEDIUM; DISSOCIATION CONSTANT; DOSE RESPONSE; EMBRYO CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HEART DEVELOPMENT; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELL; STEREOSPECIFICITY; TIME;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL NUCLEUS; DNA-BINDING PROTEINS; DYNORPHINS; EMBRYO; ENDORPHINS; ENKEPHALINS; ENZYME ACTIVATION; GATA4 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HOMEODOMAIN PROTEINS; MYOCYTES, CARDIAC; PROTEIN KINASE C; PROTEIN PRECURSORS; RECEPTORS, OPIOID; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEM CELLS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; XENOPUS PROTEINS;

EID: 0037418937     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000065169.23780.0E     Document Type: Article

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