Ambient fine and coarse particle suppression of alveolar macrophage functions

Toxicology Letters

Volumn 137, Issue 3, 2003, Pages 151-158

  Kleinman, M T ^a   Sioutas, C ^b   Chang, M C ^b   Boere, A J F ^c   Cassee, F R ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Alveolar macrophages; Coarse; Fine respiratory burst; Particulate matter; Size fractions

Indexed keywords

ENDOTOXIN; FREE RADICAL; PHORBOL 13 ACETATE 12 MYRISTATE; SUPEROXIDE;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CELL ASSAY; CELL STIMULATION; CHEMOLUMINESCENCE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE RESPONSE; IN VITRO STUDY; INCUBATION TIME; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MACROPHAGE FUNCTION; METHODOLOGY; NETHERLANDS; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; TIME; TOXICITY; TRAFFIC;

AIR POLLUTANTS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; FREE RADICALS; MACROPHAGES, ALVEOLAR; METALS; NITROGEN; PARTICLE SIZE; RATS; RATS, INBRED F344; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST; SPECIES SPECIFICITY; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE; VEHICLE EMISSIONS;

EID: 0037415397     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(02)00398-3     Document Type: Article

References (18)

1. Becker S., Soukup J.M. Decreased CD11b expression, phagocytosis, and oxidative burst in urban particulate pollution-exposed human monocytes and alveolar macrophages. J. Toxicol. Envrion. Health. 55:1998;455-477.
2. Becker S., Soukup J.M., Gilmour M.I., Devlin R.B. Stimulation of human and rat alveolar macrophages by urban air particulates: effects on oxidant radical generation and cytokine production. Toxicol. Appl. Pharmacol. 141:1996;637-648.
3. Bolarin D.M., Bhalla D.K., Kleinman M.T. Effects of repeated exposures of geriatric rats to ozone and particle-containing atmospheres: an analysis of bronchoalveolar lavage and plasma proteins. Inhal. Toxicol. 9:1997;423-434.
4. Chang M.C., Sioutas C., Cassee F.R. A mobile High- Capacity Particle Size Classifier (HCPSC) for separate collection of coarse, fine and ultrafine particles. J. Aerosol. Sci. 32:(139):2001;156.
5. Dab W., Segala C., Dor F., Festy B., Lameloise P., Le Moellec Y., Le Tertre A., Medina S., Quenel P., Wallaert B., Zmirou D. Air pollution and health: correlation or causality? The case of the relationship between exposure to particles and cardiopulmonary mortality. J. Air Waste Manage. Assoc. 51:2001;220-235.
6. Fusco D., Forastiere F., Michelozzi P., Spadea T., Ostro B., Arca M., Perucci C.A. Air pollution and hospital admissions for respiratory conditions in Rome, Italy. Eur. Respir. J. 17:2001;1143-1150.
7. Gilmour P.S., Brown D.M., Lindsay T.G., Beswick P.H., MacNee W., Donaldson K. Adverse health effects of PM10 particles: involvement of iron in generation of hydroxyl radical. Occup. Environ. Med. 53:1996;817-822.
8. Hadnagy W., Seemayer N.H. Inhibition of phagocytosis of human macrophages induced by airborne particulates. Toxicol. Lett. 72:1994;23-31.
9. Izzotti A., Camoirano A., Sciacca D.A.F.S., De Naro Papa F., Cesarone C.F., De Flora S. Biomarker alterations produced in rat lung by intratracheal instillations of air particulate extracts and chemoprevention with oral N-acetylcysteine. Cancer Res. 56:1996;1533-1538.
10. Kleinman M.T., Bufalino C., Rasmussen R., Hyde D., Bhalla D.K., Mautz W.J. Toxicity of chemical components of ambient fine particulate matter PM2.5 inhaled by aged rats. J. Appl. Toxicol. 20:2000;357-364.
11. Martin L.D., Krunkosky T.M., Dye J.A., Fischer B.M., Jiang N.F., Rochelle L.G., Akley N.J., Dreher K.L., Adler K.B. The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates. Environ. Health Perspect. 105:(Suppl. 5):1997;1301-1307.
12. Moore R., Beredjiklian P., Rhoad R., Theiss S., Cuckler J., Ducheyne P., Baker D.G. A comparison of the inflammatory potential of particulates derived from two composite materials. J. Biomed. Mater. Res. 34:1997;137-147.
13. Romieu I., Samet J.M., Smith K.R., Bruce N. Outdoor air pollution and acute respiratory infections among children in developing countries. J. Occup. Environ. Med. 44:2002;640-649.
14. Salonen R.O., Pennanen A.S., Hälinen A.I., Hirvonen M.R., Sillapäa M., Hillamo R., Karlsson V., Koskentalo T., Aarnio P., Ferguson S., Koutrakis P. A chemical and toxicological comparison of urban air PM10 collected during winter and spring in Finland. Inhal. Toxicol. 12:(2):2000;95-103.
15. Samet J. Air pollution and epidemiology: "Deja vu all over again" Epidemiology. 13:2002;118-119.
16. Schins R.P.F., Knaapen A.M., Weishaupt C., Winzer A., Borm P.J.A. Cytotoxic and inflammatory effects of coarse and fine particulate matter in macrophages and epithelial cells. Ann. Occup. Hyg. 46:(1):2002;203-206.
17. Warshawsky D., Reilman R., Cheu J., Radike M., Rice C. Influence of particle dose on the cytotoxicity of hamster and rat pulmonary alveolar macrophage in vitro. J. Toxicol. Environ. Health. 42:1994;407-421.
18. Yang H.M., Ma J.Y., Castranova V., Ma J.K. Effects of diesel exhaust particles on the release of interleukin-1 and tumor necrosis factor-alpha from rat alveolar macrophages. Exp. Lung Res. 23:1997;269-284.