Fatigue performance and cyto-toxicity of low rigidity titanium alloy, Ti-29Nb-13Ta-4.6Zr

Biomaterials

Volumn 24, Issue 16, 2003, Pages 2673-2683

  Niinomi, Mitsuo ^a  

^a TOYOHASHI UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

Beta titanium alloy; Biomedical application; Cyto toxicity; Fatigue; Low rigidity; Ti 29Nb 13Ta 4.6Zr

Indexed keywords

ELASTIC MODULI; FATIGUE OF MATERIALS; HARDNESS TESTING; PHASE TRANSITIONS; TOXICITY;

CYTO-TOXICITY;

TITANIUM ALLOYS;

ALLOY; TITANIUM;

AGING; ARTICLE; BIOMEDICINE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CYTOTOXICITY; FATIGUE; PRIORITY JOURNAL; RIGIDITY; YOUNG MODULUS;

EID: 0037411338     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(03)00069-3     Document Type: Article

References (28)

1. ASTM designation F2066-01. Standard specification for wrought titanium-15 molybdenum alloy for surgical implant applications. Philadelphia, PA: ASTM, 2001, p. 1605-8.
2. ASTM designation draft #3. Standard specification for wrought taitanium-35Niobium-7zirconium-5tantalum alloy for surgical implant applications (UNS R58350). Philadelphia, PA: ASTM, 2000.
3. ASTM designation draft #6. Standard specification for wrought titanium-3aluminun-2.5vanadium alloy seamless tubing for surgical implant applications (UNS R56320). Philadelphia, PA: ASTM, 2000.
4. Davidson JA, Georgette FS. State of the art materials for orthopedic prosthetic devices. Proceedings of the implant manufacturing and material technology. Society of Manufacturing Engineers. Dearborn, 1987: EM87-122-1-EM87-122-26.
5. Niinomi M. Recent metallic materials for biomedical applications. Metal Mater Trans A. 33A:2002;477-486.
6. Kuroda D., Niinomi M., Morinaga M., Kato Y., Yashiro T. Design and mechanical properties of new β type titanium alloys for implant materials. Mat Sci Eng A. A243:1998;244-249.
7. Niinomi M., Kuroda D., Fukunaga K., Morinaga M., Kato Y., Yashiro T., Suzuki A. Corrosion wear fracture of new β type biomedical titanium alloys. Mat Sci Eng A. A263:1999;193-199.
8. Kuroda D., Niinomi M., Fukui H., Suzuki A., Hasegawa S. Mechanical performance of newly developed β-type titanium alloy, Ti-29Nb-13Ta-4.6Zr, for biomedical applications. Niinomi M., Okabe T., Taleff E.M., Lesure D.R., Lippard H.E. Structural biomaterials for the 21st century. 2001;99-106 TMS, Warrendale.
9. Akahori T., Niinomi M., Yabunaka T., Kuroda D., Fukui H., Suzuki A., Hasegawa J. Fretting fatigue characteristics of biomedical new β titanium alloy, Ti-29Nb-13Ta-4.6Zr. Hanada S., Zhong Z., Nam S.W., Wright R.N. Proceedings of the PRICM 4. 2001;209-212 The Jpn. Inst. Metals.
10. Steinemann S.G. Corrosion of surgical implants - in vivo and in vitro tests. Winter G.D., Leray J.L., de Groot K. Evaluation of biomaterials. 1980;1-34 Wiley, New York.
11. Kawahara H., Ochi S., Tanetani K., Kato K., Isogai M., Mizuno Y., Yamamoto H., Yamaguchi A. Biological test of dental materials, Effect of pure metals upon the mouse subcutaneous fibroblast, strain L cell in tissue culture. J Jpn Soc Dent Apparat Mater. 4:1963;65-75.
12. Kudo S., Ozawa M. Application of piezoelectric composite-bar method to elastic modulus measurement of ceramics (part 1). J Ceramics Soc Japan. 98:1990;635-657.
13. Borenfreund E., Purener J.A. Toxicity determined in vitro by morphological alternations and neutral red absorption. Toxicl Lett. 24:1985;119-124.
14. Mosman T. Rapid colorimetric assay for cellular growth and survival, Application to proliferation and cytotoxicity assay. J Immunol Methods. 65:1983;55-63.
15. Jha S.K., Ravichandran K.S. Effect of mean stress (stress ratio) and aging on fatigue crack growth in a metastable beta titanium Ti-10V-2Fe-3Al. Metal Mater Trans A. 37A:2000;703-714.
16. Okazaki M., Hizume T. Effect of microstructure on small fatigue crack growth and the crack opening - closing behavior in Ti-6Al-4V alloy. J Soc Mater Sci Japan. 43:1994;1238-1244.
17. Akahori T., Niinomi M., Fukunaga K., Inagaki I. An investigation of the effect of fatigue deformation on the residual properties of Ti-6Al-4V ELI. Metall Mater Trans A. 31A:2000;1937-1948.
18. Akahori T., Niinomi M., Fukunaga K., Inagaki I. Effects of microstructure on the short fatigue crack initiation and propagation characteristics of biomedical alpha/beta titanium alloys. Metall Mater Trans A. 31A:2000;1949-1958.
19. Ruppen J., Bhowal P., Eylon D., Macevily A.J. On the process of subsurface fatigue crack initiation in Ti-6Al-4V. ASTM STP. 675:1979;47-68.
20. Lindemann J., Wagner L. Mean stress sensitivity in fatigue of alpha, alpha+beta and beta titanium alloys. Mater Sci Eng A. A234-236:1997;1118-1121.
21. Yokoyama H., Umezawa K., Nagai K., Suzuki T. Distribution of internal crack initiation sites in high-cycle fatigue for titanium alloys. ISIJ. 37:1997;1237-1244.
22. Chunbian J., Tokaji K., Nakashima M., Ogawa T. Effect of microstructure on fatigue behavior of Ti-15Mo-5Zr-3Al alloy. J Soc Mat Sci Japan. 44:1995;933-938.
23. Tokaji K., Ohya K., Kariya H. Effect of grain size on fatigue strength and substructure crack initiation in beta Ti-22V-4Al alloy. J Soc Mat Sci Japan. 49:2000;994-1001.
24. Shiozawa K., Kuroda Y., Nishino S. Effect of stress ration subsurface fatigue crack initiation behavior of beta-type titanium alloy. J Jpn Soc Mech Eng A. 64:1998;94-101.
25. Shankar P.S., Ravichandran K.S. Fatigue response and micromechanism of crack initiation in Ti-10V-2Fe-3Al titanium alloy. Boyer R.R., Eylon D., Lütjering G. Fatigue behavior of titanium alloys. 1998;135-147 TMS, Warrendale.
26. Hagiwara M. Mechanism of Fatigue of titanium alloys. Mater Jpn. 37:1998;35-38.
27. Welsch G., Bunk W. Deformation modes of the α-phase of Ti-6Al-4V as a function of oxygen concentration and aging temperature. Metal Trans A. 13A:1982;889.
28. Mishra AK, Davidson JA, Poggie RA, Kovacs P, FizGerald TJ. Mechanical and tribological properties and biocompatibility of diffusion hardened Ti-13Nb-13Zr - A new titanium alloy for surgical implants. In: Brown SA, Lemons JE, editors. Medical applications of titanium and its alloys. West Conshohocken: ASTM, 1996 STP 1272: p. 96-113.