Addition of 3-deazaadenosine to vacutainer tubes stabilizes whole-blood homocysteine for at least 6 hours at ambient temperature [1]

Clinical Chemistry

Volumn 49, Issue 5, 2003, Pages 835-

  Bowron, Ann ^a   Stansbie, David ^a  

^a BRISTOL ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEAZAADENOSINE; HOMOCYSTEINE;

BLOOD SAMPLING; DEVICE; DRUG STABILITY; ENVIRONMENTAL TEMPERATURE; LETTER; PHASE SEPARATION; TUBE; VACUUM;

ANTICOAGULANTS; BLOOD SPECIMEN COLLECTION; HEPARIN; HUMANS; TROPONIN I;

EID: 0037407190     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/49.5.835     Document Type: Letter

References (5)

1. Wald D, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002;325:1202-6.
2. Hill DM, Johnson U, Burns PJ, Neale AM, Harmening DM, Kenney AC. Effects of temperature on stability of blood homocysteine in collection tubes containing 3-deazaadenosine. Clin Chem 2002;48:2017-22.
3. Al-Khafaji F, Bowron A, Day AP, Scott J, Stansbie D. Stabilization of blood homocysteine bY 3-deazaadenosine. Ann Clin Biochem 1998;35:780-2.
4. Ubbink JB, Vermaak WJH, Bissbort S. Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum. J Chromatogr 1991;565:441-6.
5. Woltersdorf WWW, Bowron A, Day A, Scott J, Stansbie D. Abbott IMx homocysteine assay: significant interference by 3-deazaadenosine [Letter]. Ann Clin Biochem 1999;36:533.