Effect of botulinum toxin A on the autonomic nervous system of the rat lower urinary tract

Journal of Urology

Volumn 169, Issue 5, 2003, Pages 1896-1900

  Smith, Christopher P ^a   Franks, Michael E ^a   McNeil, Brian K ^a   Ghosh, Rudrani ^a   De Groat, William C ^a   Chancellor, Michael B ^a   Somogyi, George T ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Autonomic nervous system; Bladder; Botulinum toxin type A; Rats, Sprague Dawley; Urethra

Indexed keywords

ACETYLCHOLINE; BOTULINUM TOXIN A; CHOLINE; NORADRENALIN; TRITIUM;

ANIMAL EXPERIMENT; ARTICLE; AUTONOMIC NERVE; AUTONOMIC NERVOUS SYSTEM; BLADDER; CONTROLLED STUDY; DRUG EFFECT; FEMALE; INNERVATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; RAT; SCINTILLATION COUNTING; URETHRA; URINARY TRACT;

EID: 0037404247     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000049202.56189.54     Document Type: Article

References (23)

1. van Ermengem, E.: Ueber einen neuen anaeroben Bacillus and seine Beziehungen zum Botulisms. Zeutsch Hyg Infekt, 26: 1, 1897
2. Grazko, M. A., Polo, K. B. and Jabbari, B.: Botulinum toxin A for spasticity, muscle spasms, and rigidity. Neurology, 45: 712, 1995
3. Jankovic, J., Schwartz, K. and Donovan, D. T.: Botulinum toxin treatment of cranial-cervical dystonia, spasmodic dysphonia, other focal dystonias and hemifacial spasm. J Neurol Neurosurg Psychiatry, 53: 633, 1990
4. Petit, H., Wiart, E., Gaujard, E., LeBreton, F., Ferriere, J. M., Lagueny, A. et al: Botulinum A toxin treatment for detrusorsphincter dyssynergia in spinal cord disease. Spinal Cord, 36: 91, 1998
5. Dykstra, D. D. and Sidi, A.: Treatment of detrusor-sphincter dyssynergia with botulinum A toxin: a double-blind study. Arch Phys Med Rehabil, 71: 24, 1990
6. Dykstra, D. D., Sidi, A. A., Scott, A. B., Pagel, J. M. and Goldish, G. D.: Effects of botulinum A toxin on detrusor-sphincter dyssynergia in spinal cord injury patients. J Urol, 139: 919, 1988
7. Schurch, B., Stöhrer, M., Kramer, G., Schmid, D. M., Gaul, G. and Hauri, D.: Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: a new alternative to anticholinergic drugs? Preliminary results. J Urol, 164: 692, 2000
8. Schurch, B., Hauri, D., Rodic, B., Curt, A., Meyer, M. and Rossier, A. B.: Botulinum-A toxin as a treatment of detrusor-sphincter dyssynergia: a prospective study in 24 spinal cord injury patients. J Urol, 155: 1023, 1996
9. Santafe, M. M., Urbano, F. J., Lanuza, M. A. and Uchitel, O. D.: Multiple types of calcium channels mediate transmitter release during functional recovery of botulinum toxin type A-poisoned mouse motor nerve terminals. Neuroscience, 95: 227, 2000
10. de Paiva, A., Meunier, F. A., Molgo, J., Aoki, K. R. and Dolly, J. O.: Functional repair of motor endplates after botulinum neurotoxin type A poisoning: biphasic switch of synaptic activity between nerve sprouts and their parent terminals. Proc Natl Acad Sci USA, 96: 3200, 1999
11. Somogyi, G. T., Tanowitz, M., Zernova, G. and de Groat, W. C.: M1 muscarinic receptor-induced facilitation of ACh and noradrenaline release in the rat bladder is mediated by protein kinase C. J Physiol, 496: 245, 1996
12. Lopez-Alonso, E., Canaves, J., Arribas, M., Casanova, A., Marsal, J., Gonzalez-Ros, J. M. et al: Botulinum toxin type A inhibits Ca (2+)-dependent transport of acetylcholine in reconstituted giant liposomes made from presynaptic membranes from cholinergic nerve terminals. Neurosci Lett, 196: 37, 1995
13. Ashton, A. C. and Dolly, J. O.: Characterization of the inhibitory action of botulinum neurotoxin type A on the release of several transmitters from rat cerebrocortical synaptosomes. J Neurochem, 50: 1808, 1988
14. Wonnacott, S. and Marchbanks, R. M.: Inhibition by botulinum toxin of depolarization-evoked release of (14C) acetylcholine from synaptosomes in vitro. Biochem J, 156: 701, 1976
15. Ray, P.: Botulinum toxin A inhibits acetylcholine release from cultured neurons in vitro. In Vitro Cell Dev Biol Anim, 29A: 456, 1993
16. McInnes, C. and Dolly, J. O.: Ca (2+)-dependent noradrenaline release from permeabilised PC12 cells is blocked by botulinum neurotoxin A or its light chain. FEBS Lett, 261: 323, 1990
17. MacKenzie, I., Burnstock, G. and Dolly, J. O.: The effects of purified botulinum neurotoxin type A on cholinergic, adrenergic and non-adrenergic, atropine-resistant autonomic neuromuscular transmission. Neuroscience, 7: 997, 1982
18. Carpenter, F. G.: Motor responses of the urinary bladder and skeletal muscle in botulinum intoxicated rates. J Physiol, 188: 1, 1967
19. Somogyi, G. T., Tanowitz, M. and de Groat, W. C.: M1 muscarinic receptor-mediated facilitation of acetylcholine release in the rat urinary bladder. J Physiol, 480: 81, 1994
20. Shimazaki, Y., Nishiki, T., Omori, A., Sekiguchi, M., Kamata, Y., Kozaki, S. et al: Phosphorylation of 25-kDa Synaptosome-associated protein. Possible involvement in protein kinase C-mediated regulation of neurotransmitter disease. J Biol Chem, 271: 14548, 1996
21. Nakov, R, Habermann, E., Hertting, G., Wurster, S. and Allgaier, S.: Effects of botulinum A toxin on presynaptic modulation of evoked transmitter release. Eur J Pharmacol, 164: 45, 1989
22. Somogyi, G. T., Zernova, G. V., Yoshiyama, M., Yamamoto, T. and de Groat, W. C.: Frequency dependence of muscarinic facilitation of transmitter release in urinary bladder strips from neurally intact or chronic spinal cord transected rats. Br J Pharmacol, 125: 241, 1998
23. Somogyi, G. T. and de Groat, W. C.: Modulation of the release of [3H]norepinephrine form the base and body of the rat urinary bladder by endogenous adrenergic and cholinergic mechanisms. J Pharmacol Exp Ther, 255: 204, 1990