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Volumn 27, Issue 5, 2003, Pages 375-380

Pilot study of recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein (TNFR:Fc; Enbrel) in patients with refractory multiple myeloma: Increase in plasma TNFα levels during treatment

Author keywords

Enbrel; Multiple myeloma; Refractory; TNF

Indexed keywords

ETANERCEPT; TUMOR NECROSIS FACTOR ALPHA;

EID: 0037400526     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(02)00082-6     Document Type: Article
Times cited : (63)

References (41)
  • 1
    • 0028474548 scopus 로고
    • Multiple myeloma and other differentiated B-cell disorders
    • Giles F.J. Multiple myeloma and other differentiated B-cell disorders. Curr. Opin. Hematol. 1:1994;278-284.
    • (1994) Curr. Opin. Hematol. , vol.1 , pp. 278-284
    • Giles, F.J.1
  • 2
    • 0028793829 scopus 로고
    • Refractory multiple myeloma: Recent advances in therapy
    • Giles F.J. Refractory multiple myeloma: recent advances in therapy. Hematol. Pathol. 9:1995;121-140.
    • (1995) Hematol. Pathol. , vol.9 , pp. 121-140
    • Giles, F.J.1
  • 3
    • 0021322023 scopus 로고
    • Effective treatment of advanced multiple myeloma refractory to alkylating agents
    • Barlogie B., Smith L., Alexanian R. Effective treatment of advanced multiple myeloma refractory to alkylating agents. New Engl. J. Med. 310:1984;1353-1356.
    • (1984) New Engl. J. Med. , vol.310 , pp. 1353-1356
    • Barlogie, B.1    Smith, L.2    Alexanian, R.3
  • 4
    • 0035880229 scopus 로고    scopus 로고
    • Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: Identification of prognostic factors in a Phase 2 study of 169 patients
    • Barlogie B., Desikan R., Eddlemon P.et al. Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a Phase 2 study of 169 patients. Blood. 98:2001;492-494.
    • (2001) Blood , vol.98 , pp. 492-494
    • Barlogie, B.1    Desikan, R.2    Eddlemon, P.3
  • 5
    • 0032748385 scopus 로고    scopus 로고
    • Anti-tumor activity of thalidomide in refractory multiple myeloma
    • Singhal S., Mehta J., Desikan R.et al. Anti-tumor activity of thalidomide in refractory multiple myeloma. New Engl. J. Med. 341:1999;1565-1571.
    • (1999) New Engl. J. Med. , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 7
    • 0031985198 scopus 로고    scopus 로고
    • Multiple myeloma: Increasing evidence for a multistep transformation process
    • Hallek M., Leif Bergsagel P., Anderson K.C. Multiple myeloma: increasing evidence for a multistep transformation process. Blood. 91:1998;3-21.
    • (1998) Blood , vol.91 , pp. 3-21
    • Hallek, M.1    Leif Bergsagel, P.2    Anderson, K.C.3
  • 8
    • 0027980663 scopus 로고
    • TNF and IL-6 are potent growth factors for OH-2: A novel human myeloma cell line
    • Borset M., Waage A., Brekke O.L., Helseth E. TNF and IL-6 are potent growth factors for OH-2: a novel human myeloma cell line. Eur. J. Haematol. 536:1994;31-37.
    • (1994) Eur. J. Haematol. , vol.536 , pp. 31-37
    • Borset, M.1    Waage, A.2    Brekke, O.L.3    Helseth, E.4
  • 9
    • 0030176053 scopus 로고    scopus 로고
    • The role of the two TNF receptors in proliferation, NF-Kappa B activation and discrimination between TNF and LT α signalling in the human myeloma cell line OH-2
    • Borset M., Medvedev A., Sundan A., Espevik T. The role of the two TNF receptors in proliferation, NF-Kappa B activation and discrimination between TNF and LT α signalling in the human myeloma cell line OH-2. Cytokine. 8:1996;430-438.
    • (1996) Cytokine , vol.8 , pp. 430-438
    • Borset, M.1    Medvedev, A.2    Sundan, A.3    Espevik, T.4
  • 10
    • 0025274112 scopus 로고
    • Autocrine growth by two cytokines, interleukin-6 and tumor necrosis factor α, in the myeloma cell line KHM-1A
    • Hata H., Matsuzaki H., Takatsuki K. Autocrine growth by two cytokines, interleukin-6 and tumor necrosis factor α, in the myeloma cell line KHM-1A. Acta Haematol. 83:1990;133-136.
    • (1990) Acta Haematol. , vol.83 , pp. 133-136
    • Hata, H.1    Matsuzaki, H.2    Takatsuki, K.3
  • 11
    • 0030039882 scopus 로고    scopus 로고
    • Cytokines (IL-6, TNFα, IL-1α) and soluble interleukin-2 receptor as serum tumor markers in multiple myeloma
    • Filella X., Blade J., Guillermo A., Molina R., Rozman C., Ballesta A. Cytokines (IL-6, TNFα, IL-1α) and soluble interleukin-2 receptor as serum tumor markers in multiple myeloma. Ca Detecti. Prevent. 20:1996;52-56.
    • (1996) Ca Detecti. Prevent. , vol.20 , pp. 52-56
    • Filella, X.1    Blade, J.2    Guillermo, A.3    Molina, R.4    Rozman, C.5    Ballesta, A.6
  • 12
    • 0021069905 scopus 로고
    • An interleukin-1 like factor stimulates bone resorption in vitro
    • Gowen M., Wood D.D., Ihrie E.J., McGuire M.K., Russell R.G. An interleukin-1 like factor stimulates bone resorption in vitro. Nature. 306:1983;378-380.
    • (1983) Nature , vol.306 , pp. 378-380
    • Gowen, M.1    Wood, D.D.2    Ihrie, E.J.3    McGuire, M.K.4    Russell, R.G.5
  • 13
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
    • Bertolini D.R., Nedwin G.E., Bringman T.S., Smith D.D., Mundy G.R. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature. 319:1986;516-518.
    • (1986) Nature , vol.319 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 14
    • 0030016476 scopus 로고    scopus 로고
    • Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors
    • Torcia M., Lucibello M., Edouard V.et al. Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors. Exp. Hematol. 24:1996;868-874.
    • (1996) Exp. Hematol. , vol.24 , pp. 868-874
    • Torcia, M.1    Lucibello, M.2    Edouard, V.3
  • 15
    • 0031037640 scopus 로고    scopus 로고
    • New insight in the clinical biology of myltiple myeloma
    • Bataille R. New insight in the clinical biology of myltiple myeloma. Sem. Hematol. 34:1997;23-28.
    • (1997) Sem. Hematol. , vol.34 , pp. 23-28
    • Bataille, R.1
  • 16
    • 0030065539 scopus 로고    scopus 로고
    • Differential mobilization of myeloma cells and normal hematopoietic stem cells in multiple myeloma after treatment with cyclophosphamide and granulocyte-macrophage colony-stimulating factor
    • Gazitt Y., Tian E., Barlogie B.et al. Differential mobilization of myeloma cells and normal hematopoietic stem cells in multiple myeloma after treatment with cyclophosphamide and granulocyte-macrophage colony-stimulating factor. Blood. 87:1996;805-811.
    • (1996) Blood , vol.87 , pp. 805-811
    • Gazitt, Y.1    Tian, E.2    Barlogie, B.3
  • 17
    • 0024419152 scopus 로고
    • Production of cytokines by bone marrow cells obtained from patients with multiple myeloma
    • Lichtenstein A., Berenson J.R., Norman D., Chang M.P., Carlile A. Production of cytokines by bone marrow cells obtained from patients with multiple myeloma. Blood. 74:1989;1266-1273.
    • (1989) Blood , vol.74 , pp. 1266-1273
    • Lichtenstein, A.1    Berenson, J.R.2    Norman, D.3    Chang, M.P.4    Carlile, A.5
  • 18
    • 0025313006 scopus 로고
    • A receptor for tumor necosis factor defines an unusual family of cellular and viral proteins
    • Smith C.A., Davis T., Anderson D.et al. A receptor for tumor necosis factor defines an unusual family of cellular and viral proteins. Science. 248:1990;1019-1023.
    • (1990) Science , vol.248 , pp. 1019-1023
    • Smith, C.A.1    Davis, T.2    Anderson, D.3
  • 19
    • 0025269050 scopus 로고
    • Molecular cloning and expression of the human 55 kDa tumor necrosis factor receptor
    • Loetscher H., Pan Y.C., Lahm H.W.et al. Molecular cloning and expression of the human 55 kDa tumor necrosis factor receptor. Cell. 61:1990;351-359.
    • (1990) Cell , vol.61 , pp. 351-359
    • Loetscher, H.1    Pan, Y.C.2    Lahm, H.W.3
  • 20
    • 0027198002 scopus 로고
    • Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists
    • Mohler K.M., Torrance D.S., Smith C.A.et al. Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J. Immunol. 151:1993;1548-1561.
    • (1993) J. Immunol. , vol.151 , pp. 1548-1561
    • Mohler, K.M.1    Torrance, D.S.2    Smith, C.A.3
  • 21
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • Moreland L.W., Baumgartner S.W., Schiff M.H.et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. New Engl. J. Med. 337:1997;141-147.
    • (1997) New Engl. J. Med. , vol.337 , pp. 141-147
    • Moreland, L.W.1    Baumgartner, S.W.2    Schiff, M.H.3
  • 23
    • 0033856364 scopus 로고    scopus 로고
    • Etanercept and urticaria in patients with juvenile idiopathic arthritis
    • Skytta E., Pohjankoski H., Savolainen A.et al. Etanercept and urticaria in patients with juvenile idiopathic arthritis. Clin. Exp. Rheumatol. 18:2000;533-534.
    • (2000) Clin. Exp. Rheumatol. , vol.18 , pp. 533-534
    • Skytta, E.1    Pohjankoski, H.2    Savolainen, A.3
  • 24
    • 0033768517 scopus 로고    scopus 로고
    • Etanercept (Enbrel): Update on therapeutic use
    • Spencer-Green G. Etanercept (Enbrel): update on therapeutic use. Ann. Rheum. Dis. 59:2000;i46-49.
    • (2000) Ann. Rheum. Dis. , vol.59 , pp. 46-49
    • Spencer-Green, G.1
  • 25
    • 0035033807 scopus 로고    scopus 로고
    • Etanercept combined with conventional treatment in Wegener's granulomatosis: A 6 months open-label trial to evaluate safety
    • Stone J.H., Uhlfelder M.L., Hellmann D.B., Crook S., Bedocs N.M., Hoffman G.S. Etanercept combined with conventional treatment in Wegener's granulomatosis: a 6 months open-label trial to evaluate safety. Arthritis Rheum. 44:2001;1149-1154.
    • (2001) Arthritis Rheum. , vol.44 , pp. 1149-1154
    • Stone, J.H.1    Uhlfelder, M.L.2    Hellmann, D.B.3    Crook, S.4    Bedocs, N.M.5    Hoffman, G.S.6
  • 26
    • 0000589599 scopus 로고
    • Recombinant soluble tumor necrosis factor (TNF) receptor (TNFC:Fc): safety and pharmacokinetics in human volunteers
    • Nam MH, Reda D, Boujoukos AJ, Agosti J, Suffredini AF. Recombinant soluble tumor necrosis factor (TNF) receptor (TNFC:Fc): safety and pharmacokinetics in human volunteers. Clin Res 1993;41.
    • (1993) Clin Res , pp. 41
    • Nam, M.H.1    Reda, D.2    Boujoukos, A.J.3    Agosti, J.4    Suffredini, A.F.5
  • 27
    • 0035957036 scopus 로고    scopus 로고
    • Results of targeted anti-tumor necrosis factor therapy with etanercept (Enbrel) in patients with advanced heart failure
    • Bozkurt B., Torre-Amione G., Warren M.S.et al. Results of targeted anti-tumor necrosis factor therapy with etanercept (Enbrel) in patients with advanced heart failure. Circulation. 103:2001;1044-1047.
    • (2001) Circulation , vol.103 , pp. 1044-1047
    • Bozkurt, B.1    Torre-Amione, G.2    Warren, M.S.3
  • 28
    • 0033614816 scopus 로고    scopus 로고
    • Safety and efficacy of a soluble p75 tumor necrosis factor receptor (Enbrel, etanercept) in patients with advanced heart failure
    • Deswal A., Bozkurt B., Seta Y.et al. Safety and efficacy of a soluble p75 tumor necrosis factor receptor (Enbrel, etanercept) in patients with advanced heart failure. Circulation. 99:1999;3224-3226.
    • (1999) Circulation , vol.99 , pp. 3224-3226
    • Deswal, A.1    Bozkurt, B.2    Seta, Y.3
  • 29
    • 0029900294 scopus 로고    scopus 로고
    • Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein
    • Fisher C.J.J., Agosti J.M., Opal S.M.et al. Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein. New Engl. J. Med. 334:1996;1697-1702.
    • (1996) New Engl. J. Med. , vol.334 , pp. 1697-1702
    • Fisher, C.J.J.1    Agosti, J.M.2    Opal, S.M.3
  • 30
    • 0028957549 scopus 로고
    • Efficacy and safety of monoclonal antibody to human tumor necrosis factor α in patients with sepsis syndrome: A randomized, controlled, double-blind, multicenter clinical trial
    • Abraham E., Wunderink R., Silverman H. Efficacy and safety of monoclonal antibody to human tumor necrosis factor α in patients with sepsis syndrome: a randomized, controlled, double-blind, multicenter clinical trial. JAMA. 273:1995;934-941.
    • (1995) JAMA , vol.273 , pp. 934-941
    • Abraham, E.1    Wunderink, R.2    Silverman, H.3
  • 32
    • 0003506745 scopus 로고    scopus 로고
    • Bethesda (MD): Division of Cancer Treatment, National Cancer Institute
    • Institute NC. Guidelines for reporting of adverse drug reactions. Bethesda (MD): Division of Cancer Treatment, National Cancer Institute, 1998.
    • (1998) Guidelines for Reporting of Adverse Drug Reactions
  • 33
    • 0016804136 scopus 로고
    • A clinical staging system for multiple myeloma: Correlation of measured myeloma cell mass with presenting features, response to treatment, and survival
    • Durie B.G.M., Salmon S.E. A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting features, response to treatment, and survival. Cancer. 36:1975;842.
    • (1975) Cancer , vol.36 , pp. 842
    • Durie, B.G.M.1    Salmon, S.E.2
  • 34
    • 0034930533 scopus 로고    scopus 로고
    • Etanercept in rheumatoid arthritis
    • Alldred A. Etanercept in rheumatoid arthritis. Exp. Opin. Pharmacother. 2:2001;1137-1148.
    • (2001) Exp. Opin. Pharmacother. , vol.2 , pp. 1137-1148
    • Alldred, A.1
  • 35
    • 0035056003 scopus 로고    scopus 로고
    • Anti-TNFα therapy of rheumatoid arthritis: What we have learned?
    • Feldmann M., Maini R.N. Anti-TNFα therapy of rheumatoid arthritis: what we have learned? Ann. Rev. Immunol. 19:2001;163-196.
    • (2001) Ann. Rev. Immunol. , vol.19 , pp. 163-196
    • Feldmann, M.1    Maini, R.N.2
  • 36
    • 0030025253 scopus 로고    scopus 로고
    • Evaluation of recombinant human soluble dimeric tumor necrosis factor receptor for prevention of OKT3-associated acute clinical syndrome
    • Eason J.D., Pascual M., Wee S.et al. Evaluation of recombinant human soluble dimeric tumor necrosis factor receptor for prevention of OKT3-associated acute clinical syndrome. Transplantation. 61:1996;224-228.
    • (1996) Transplantation , vol.61 , pp. 224-228
    • Eason, J.D.1    Pascual, M.2    Wee, S.3
  • 37
    • 79960971035 scopus 로고    scopus 로고
    • Genetic polymorphism in the tumor necrosis factor-α locus influences the outcome to thalidomide therapy in relapsed and refractory multiple myeloma
    • Orlando: ASH
    • Neben K, Mytilineos J, Moehler TM, et al. Genetic polymorphism in the tumor necrosis factor-α locus influences the outcome to thalidomide therapy in relapsed and refractory multiple myeloma, vol. 98. Blood. Orlando: ASH, 2001.
    • (2001) Blood , vol.98
    • Neben, K.1    Mytilineos, J.2    Moehler, T.M.3
  • 38
    • 85112365005 scopus 로고    scopus 로고
    • Effect of in vitro administration of TNF receptor fusion protein (TNFR:Fc) on the biological characteristics of AML cells
    • San Francisco (CA): ASH
    • Sivaraman S, Deshpande G, Tao M, et al. Effect of in vitro administration of TNF receptor fusion protein (TNFR:Fc) on the biological characteristics of AML cells, vol. 96. Blood. San Francisco (CA): ASH, 2000.
    • (2000) Blood , vol.96
    • Sivaraman, S.1    Deshpande, G.2    Tao, M.3
  • 39
    • 0002670776 scopus 로고    scopus 로고
    • Combination of thalidomide and Enbrel for the treatment of patients with myelodysplastic Syndromes
    • Orlando: ASH
    • Raza A, Dutt D, Lisak L, et al. Combination of thalidomide and Enbrel for the treatment of patients with myelodysplastic Syndromes, vol. 96. Blood. Orlando: ASH, 2001.
    • (2001) Blood , pp. 96
    • Raza, A.1    Dutt, D.2    Lisak, L.3
  • 40
    • 79960970939 scopus 로고    scopus 로고
    • Etanercept palliates constitutional symptoms in myelofibrosis with myeloid metaplasia: Results of a Pilot Study
    • Orlando: ASH
    • Steensma DP, Mesa RA, Li CY, et al. Etanercept palliates constitutional symptoms in myelofibrosis with myeloid metaplasia: Results of a Pilot Study, vol. 96, Blood. Orlando: ASH. 2001.
    • (2001) Blood , vol.96
    • Steensma, D.P.1    Mesa, R.A.2    Li, C.Y.3


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