메뉴 건너뛰기




Volumn 12, Issue 4, 2003, Pages 683-688

Entecavir: A potent new antiviral drug for hepatitis B

Author keywords

Entecavir; Hepatitis B; Nucleoside analogue; Review; Treatment

Indexed keywords

9 (3 HYDROXY 2 PHOSPHONOMETHOXYPROPYL)ADENINE; ADEFOVIR; ADEFOVIR DIPIVOXIL; ALPHA INTERFERON; ANTIVIRUS AGENT; CIDOFOVIR; CIRCULAR DNA; CLEVUDINE; DEOXYGUANOSINE DERIVATIVE; DNA DIRECTED DNA POLYMERASE GAMMA; ENTECAVIR; FIALURIDINE; HEPATITIS B ANTIBODY; HEPATITIS B CORE ANTIGEN; LAMIVUDINE; LOBUCAVIR; MITOCHONDRIAL DNA; NEW DRUG; NUCLEOSIDE ANALOG; PENCICLOVIR; PLACEBO; TENOFOVIR; VIRUS DNA;

EID: 0037398391     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.12.4.683     Document Type: Review
Times cited : (54)

References (29)
  • 1
    • 0027378724 scopus 로고
    • Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis
    • WONG DK, CHEUNG AM, O'ROURKE K, NAYLOR CD, DETSKY AS, HEATHCOTE J: Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann. Intern. Med. (1993) 119:312-323.
    • (1993) Ann. Intern. Med. , vol.119 , pp. 312-323
    • Wong, D.K.1    Cheung, A.M.2    O'rourke, K.3    Naylor, C.D.4    Detsky, A.S.5    Heathcote, J.6
  • 2
    • 0035189597 scopus 로고    scopus 로고
    • Chronic hepatitis B
    • LOK AS, MCMAHON BJ: Chronic hepatitis B. Hepatology (2001) 34(6):1225-1241.
    • (2001) Hepatology , vol.34 , Issue.6 , pp. 1225-1241
    • Lok, A.S.1    Mcmahon, B.J.2
  • 3
    • 0032907705 scopus 로고    scopus 로고
    • Metabolic studies on BMS-200475, a new antiviral compound active against hepatitis B virus
    • YAMANAKA G, WILSON T, INNAIMO S et al.: Metabolic studies on BMS-200475, a new antiviral compound active against hepatitis B virus. Antimicrob. Agents Chemother. (1999) 43(1):190-193.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , Issue.1 , pp. 190-193
    • Yamanaka, G.1    Wilson, T.2    Innaimo, S.3
  • 4
    • 0031761652 scopus 로고    scopus 로고
    • In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir
    • SEIFER M, HAMATAKE RK, COLONNO RJ, STANDRING DN: In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir. Antimicrob. Agents Chemother. (1998) 42(12):3200-3208.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , Issue.12 , pp. 3200-3208
    • Seifer, M.1    Hamatake, R.K.2    Colonno, R.J.3    Standring, D.N.4
  • 6
    • 0035890097 scopus 로고    scopus 로고
    • Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection
    • COLONNO RJ, GENOVESI EV, MEDINA I et al.: Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection. J. Infect. Dis. (2001) 184(10):1236-1245.
    • (2001) J. Infect. Dis. , vol.184 , Issue.10 , pp. 1236-1245
    • Colonno, R.J.1    Genovesi, E.V.2    Medina, I.3
  • 7
    • 0031728652 scopus 로고    scopus 로고
    • Efficacy of the carbocyclic 2′-deoxyguanosine nucleoside BMS-200475 in the woodchuck model of hepatitis B virus infection
    • GENOVESI EV, LAMB L, MEDINA I et al.: Efficacy of the carbocyclic 2′-deoxyguanosine nucleoside BMS-200475 in the woodchuck model of hepatitis B virus infection. Antimicrob. Agents Chemother. (1998) 42(12):3209-3217.
    • (1998) Antimicrob. Agents Chemother , vol.42 , Issue.12 , pp. 3209-3217
    • Genovesi, E.V.1    Lamb, L.2    Medina, I.3
  • 8
    • 0030776176 scopus 로고    scopus 로고
    • Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus
    • MORALEDA G, SAPUTELLI J, ALDRICH CE, AVERETT D, CONDREAY L, MASON WS: Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus. J. Virol. (1997) 71(12):9392-9399.
    • (1997) J. Virol. , vol.71 , Issue.12 , pp. 9392-9399
    • Moraleda, G.1    Saputelli, J.2    Aldrich, C.E.3    Averett, D.4    Condreay, L.5    Mason, W.S.6
  • 9
    • 0034234540 scopus 로고    scopus 로고
    • Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA
    • DANDRI M, BURDA MR, WILL H, PETERSEN J: Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA. Hepatology (2000) 32:139-146.
    • (2000) Hepatology , vol.32 , pp. 139-146
    • Dandri, M.1    Burda, M.R.2    Will, H.3    Petersen, J.4
  • 10
    • 0036140134 scopus 로고    scopus 로고
    • Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation
    • DANDRI M, BURDA MR, BURKLE A et al.: Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation. Hepatology (2002) 35(1):217-223.
    • (2002) Hepatology , vol.35 , Issue.1 , pp. 217-223
    • Dandri, M.1    Burda, M.R.2    Burkle, A.3
  • 11
    • 0032817797 scopus 로고    scopus 로고
    • Emergence of drug-resistant populations of woodchuck hepatitis virus in woodchucks treated with the antiviral nucleoside lamivudine
    • ZHOU T, SAPUTELLI J, ALDRICH CE, DESLAURIERS M, CONDREAY LD, MASON WS: Emergence of drug-resistant populations of woodchuck hepatitis virus in woodchucks treated with the antiviral nucleoside lamivudine. Antimicrob. Agents Chemother. (1999) 43(8):1947-1954.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , Issue.8 , pp. 1947-1954
    • Zhou, T.1    Saputelli, J.2    Aldrich, C.E.3    Deslauriers, M.4    Condreay, L.D.5    Mason, W.S.6
  • 12
    • 0036136637 scopus 로고    scopus 로고
    • Potent efficacy of entecavir (BMS-200475) in a duck model of hepatitis B virus replication
    • MARION PL, SALAZAR FH, WINTERS MA, COLONNO RJ: Potent efficacy of entecavir (BMS-200475) in a duck model of hepatitis B virus replication. Antimicrob. Agents Chemother. (2002) 46(1):82-88.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , Issue.1 , pp. 82-88
    • Marion, P.L.1    Salazar, F.H.2    Winters, M.A.3    Colonno, R.J.4
  • 13
    • 0028817865 scopus 로고
    • Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B
    • MCKENZIE R, FRIED MW, SALLIE R et al.: Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N. Engl. J. Med. (1995) 333:1099-1105.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1099-1105
    • Mckenzie, R.1    Fried, M.W.2    Sallie, R.3
  • 14
    • 8544249855 scopus 로고    scopus 로고
    • Mitochondrial injury. Lessons from the fialuridine trial
    • HONKOOP P, SCHOLTE HR, DE MAN RA, SCHALM SW: Mitochondrial injury. Lessons from the fialuridine trial. Drug Saf. (1997) 17(1):1-7.
    • (1997) Drug Saf. , vol.17 , Issue.1 , pp. 1-7
    • Honkoop, P.1    Scholte, H.R.2    De Man, R.A.3    Schalm, S.W.4
  • 15
    • 0242698006 scopus 로고    scopus 로고
    • Bristol-Myers Squibb: Data on file
    • BRISTOL-MYERS SQUIBB: Data on file (2001).
    • (2001)
  • 16
    • 0034867425 scopus 로고    scopus 로고
    • Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection
    • DE MAN RA, WOLTERS LM, NEVENS F et al.: Safety and efficacy of oral entecavir given for 28 days in patients with chronic hepatitis B virus infection. Hepatology (2001) 34(3):578-582.
    • (2001) Hepatology , vol.34 , Issue.3 , pp. 578-582
    • De Man, R.A.1    Wolters, L.M.2    Nevens, F.3
  • 17
  • 18
    • 0033839986 scopus 로고    scopus 로고
    • Acute exacerbation of chronic hepatitis B virus infection after withdrawal of lamivudine therapy
    • HONKOOP P, DE MAN RA, NIESTERS HG, ZONDERVAN PE, SCHALM SW: Acute exacerbation of chronic hepatitis B virus infection after withdrawal of lamivudine therapy. Hepatology (2000) 32(3):635-639.
    • (2000) Hepatology , vol.32 , Issue.3 , pp. 635-639
    • Honkoop, P.1    De Man, R.A.2    Niesters, H.G.3    Zondervan, P.E.4    Schalm, S.W.5
  • 19
    • 0035991456 scopus 로고    scopus 로고
    • Viral dynamics during and after entecavir therapy in patients with chronic hepatitis B
    • WOLTERS LM, HANSEN BE, NIESTERS HG, DEHERTOGH D, DE MAN RA: Viral dynamics during and after entecavir therapy in patients with chronic hepatitis B. J. Hepatol. (2002) 37(1):137-144.
    • (2002) J. Hepatol. , vol.37 , Issue.1 , pp. 137-144
    • Wolters, L.M.1    Hansen, B.E.2    Niesters, H.G.3    Dehertogh, D.4    De Man, R.A.5
  • 20
    • 0000545420 scopus 로고    scopus 로고
    • Effectiveness of a low dose of entecavir in treating recurrent viremia in chronic hepatitis B
    • NEVENS F, DE MAN RA, CHUA D et al.: Effectiveness of a low dose of entecavir in treating recurrent viremia in chronic hepatitis B. Hepatology (2000) 32:A869.
    • (2000) Hepatology , vol.32
    • Nevens, F.1    De Man, R.A.2    Chua, D.3
  • 21
    • 0036892435 scopus 로고    scopus 로고
    • Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection
    • LAI CL, ROSMAWATI M, LAO J et al.: Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection. Gastroenterology (2002) 123(6):1831-1838.
    • (2002) Gastroenterology , vol.123 , Issue.6 , pp. 1831-1838
    • Lai, C.L.1    Rosmawati, M.2    Lao, J.3
  • 22
    • 0030875066 scopus 로고    scopus 로고
    • Lamivudine resistance in immunocompetent chronic hepatitis B. Incidence and patterns
    • HONKOOP P, NIESTERS HG, DE MAN RA, OSTERHAUS AD, SCHALM SW: Lamivudine resistance in immunocompetent chronic hepatitis B. Incidence and patterns. J. Hepatol. (1997) 26(6):1393-1395.
    • (1997) J. Hepatol. , vol.26 , Issue.6 , pp. 1393-1395
    • Honkoop, P.1    Niesters, H.G.2    De Man, R.A.3    Osterhaus, A.D.4    Schalm, S.W.5
  • 23
    • 0033014669 scopus 로고    scopus 로고
    • Antiviral therapy for hepatitis B and C in Asians
    • LAI CL: Antiviral therapy for hepatitis B and C in Asians. J. Gastroenterol. Hepatol. (1999) 14(Suppl.):S19-S21.
    • (1999) J. Gastroenterol. Hepatol. , vol.14 , Issue.SUPPL.
    • Lai, C.L.1
  • 24
    • 0036071201 scopus 로고    scopus 로고
    • Identification of a new variant in the YMDD motif of the hepatitis B virus polymerase gene selected during lamivudine therapy
    • NIESTERS HG, DE MAN RA, PAS SD, FRIES E, OSTERHAUS AD: Identification of a new variant in the YMDD motif of the hepatitis B virus polymerase gene selected during lamivudine therapy. J. Med. Microbiol. (2002) 51(8):695-699.
    • (2002) J. Med. Microbiol. , vol.51 , Issue.8 , pp. 695-699
    • Niesters, H.G.1    De Man, R.A.2    Pas, S.D.3    Fries, E.4    Osterhaus, A.D.5
  • 25
    • 0035114188 scopus 로고    scopus 로고
    • The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance
    • ONO SK, KATO N, SHIRATORI Y et al.: The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance. J. Clin. Invest. (2001) 107:449-455.
    • (2001) J. Clin. Invest. , vol.107 , pp. 449-455
    • Ono, S.K.1    Kato, N.2    Shiratori, Y.3
  • 26
    • 0035991863 scopus 로고    scopus 로고
    • Efficacies of Entecavir against Lamivudine-Resistant Hepatitis B Virus Replication and Recombinant Polymerases In vitro
    • LEVINE S, HERNANDEZ D, YAMANAKA G et al.: Efficacies of Entecavir against Lamivudine-Resistant Hepatitis B Virus Replication and Recombinant Polymerases In vitro. Antimicrob. Agents Chemother. (2002) 46(8):2525-2532.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , Issue.8 , pp. 2525-2532
    • Levine, S.1    Hernandez, D.2    Yamanaka, G.3
  • 27
    • 0038086225 scopus 로고    scopus 로고
    • Sustained viral load and ALT reduction following 48 weeks of entecavir treatment in subjects with chronic hepatitis B who have failed lamivudine
    • CHANG TT, HADZIYANNIS S, CIANCIARA J et al.: Sustained viral load and ALT reduction following 48 weeks of entecavir treatment in subjects with chronic hepatitis B who have failed lamivudine. Hepatology (2002) 36:A550.
    • (2002) Hepatology , vol.36
    • Chang, T.T.1    Hadziyannis, S.2    Cianciara, J.3
  • 28
    • 0034235905 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants
    • PERRILLO R, SCHIFF ER, YOSHIDA E et al.: Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants. Hepatology (2000) 32:129-134.
    • (2000) Hepatology , vol.32 , pp. 129-134
    • Perrillo, R.1    Schiff, E.R.2    Yoshida, E.3
  • 29
    • 0011875570 scopus 로고    scopus 로고
    • Entecavir significantly reduces viral load in liver transplant recipients failing lamivudine therapy for HBV
    • SHAKIL A, LILLY L, ANGUS P et al.: Entecavir significantly reduces viral load in liver transplant recipients failing lamivudine therapy for HBV. J. Hepatol (2002) 36:122.
    • (2002) J. Hepatol , vol.36 , pp. 122
    • Shakil, A.1    Lilly, L.2    Angus, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.