The efflux pump inhibitor Phe-Arg-β-naphthylamide does not abolish the activity of the Stenotrophomonas maltophilia SmeDEF multidrug efflux pump [4]

Journal of Antimicrobial Chemotherapy

Volumn 51, Issue 4, 2003, Pages 1042-1045

  Sánchez, Patricia ^a   Le, Uyen ^a   Martínez, José L ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Antibiotic efflux pumps; Antibiotic resistance; MDR inhibitors; Stenotrophomonas maltophilia

Indexed keywords

CHLORAMPHENICOL; CIPROFLOXACIN; ERYTHROMYCIN; MULTIDRUG RESISTANCE PROTEIN; N BENZOYLARGININE 2 NAPHTHYLAMIDE; NALIDIXIC ACID; PROTEIN INHIBITOR; QUINOLONE DERIVATIVE; TETRACYCLINE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; GENE OVEREXPRESSION; GROWTH INHIBITION; LETTER; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PLASMID; STENOTROPHOMONAS MALTOPHILIA; STRAIN DIFFERENCE; WILD TYPE;

DIPEPTIDES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; MEMBRANE TRANSPORT MODULATORS; MEMBRANE TRANSPORT PROTEINS; MICROBIAL SENSITIVITY TESTS; STENOTROPHOMONAS MALTOPHILIA;

EID: 0037397295     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg181     Document Type: Letter

References (6)

1. Lomovskaya, O., Warren, M. S., Lee, A., Galazzo, J., Fronko, R., Lee, M. et al. (2001). Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: Novel agents for combination therapy. Antimicrobial Agents and Chemotherapy 45, 105-16.
2. Ribera, A., Ruiz, J., de Anta, M. T. J. & Vila, J. (2002). Effect of an efflux pump inhibitor on the MIC of nalidixic acid for Acinetobacter baumannii and Stenotrophomonas maltophilia clinical isolates. Journal of Antimicrobial Chemotherapy 49, 697-8.
3. Alonso, A. & Martinez, J. L. (2001). Expression of multidrug efflux pump SmeDEF by clinical isolates of Stenotrophomonas maltophilia. Antimicrobial Agents and Chemotherapy 45, 1879-81.
4. Alonso, A. & Martinez, J. L. (2000). Cloning and characterization of SmeDEF, a novel multidrug efflux pump from Stenotrophomonas maltophilia. Antimicrobial Agents and Chemotherapy 44, 3079-86.
5. Zhang, L., Li, X. Z. & Poole, K. (2001). SmeDEF multidrug efflux pump contributes to intrinsic multidrug resistance in Stenotrophomonas maltophilia. Antimicrobial Agents and Chemotherapy 45, 3497-503.
6. Mazzariol, A., Tokue, Y., Kanegawa, T. M., Cornaglia, G. & Nikaido, H. (2000). High-level fluoroquinolone-resistant clinical isolates of Escherichia coli overproduce multidrug efflux protein AcrA. Antimicrobial Agents and Chemotherapy 44, 3441-3.