Application of 1-butyl-3-methylimidazolium hexafluorophosphate to Ir(I)-catalyzed hydrogen isotope exchange labelling of substrates poorly soluble in dichloromethane

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 46, Issue 5, 2003, Pages 489-498

  Salter, Rhys ^a   Bosser, Isabelle ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Alternative solvent to dichloromethane; Ionic liquids; Iridium catalyzed isotopic hydrogen exchange labelling; Labelling of polar compounds

Indexed keywords

CARRIER MOBILITY; CATALYSIS; DEUTERIUM; DICHLOROMETHANE; HYDROGEN; ION EXCHANGE; IRIDIUM COMPOUNDS; SOLVENTS; SUBSTRATES;

1-BUTYL-3-METHYL-IMIDAZOLIUM HEXAFLUOROPHOSPHATE; ALTERNATIVE SOLVENT TO DICHLOROMETHANE; ALTERNATIVE SOLVENTS; HYDROGEN EXCHANGE; HYDROGEN ISOTOPE EXCHANGE; IRIDIUM CATALYZED ISOTOPIC HYDROGEN EXCHANGE LABELING; LABELING OF POLAR COMPOUND; LABELINGS; POLAR COMPOUNDS;

IONIC LIQUIDS;

1 BUTYL 3 METHYLIMIDAZOLIUM HEXAFLUOROPHOSPHATE; ACETANILIDE DERIVATIVE; BENZAMIDE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; DEUTERIUM; DICHLOROMETHANE; IMIDAZOLE DERIVATIVE; IRIDIUM; N (4 METHOXYPHENYL) N METHYLBENZAMIDE; SOLVENT; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; DISSOLUTION; ISOTOPE LABELING; SOLUBILITY;

TRITIUM;

EID: 0037396205     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.692     Document Type: Article

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