Long-term benefits and repeated treatment cycles of intra-articular sodium hyaluronate (Hyalgan) in patients with osteoarthritis of the knee

Seminars in Arthritis and Rheumatism

Volumn 32, Issue 5, 2003, Pages 310-319

  Kolarz, Gernot ^a   Kotz, Rainer ^b   Hochmayer, Ingrid ^c  

^a Institut fur Rheumatologie der Kurstadt Baden   (Austria)

^b University of Vienna   (Austria)

^c ZAK Pharma Dienstleistung GesMBH   (Austria)

Author keywords

Hyalgan; Osteoarthritis; Pain management; Repeated long term efficacy; Sodium hyaluronate; Treatment cycles

Indexed keywords

HYALURONIC ACID;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FOLLOW UP; HUMAN; JOINT EFFUSION; KNEE FUNCTION; KNEE OSTEOARTHRITIS; KNEE PAIN; LONG TERM CARE; MALE; PAIN ASSESSMENT; PRIORITY JOURNAL; PRURITUS; RASH; VISUAL ANALOG SCALE; WALKING;

EID: 0037393877     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1053/sarh.2002.50013     Document Type: Article

References (26)

1. Niethard FU, Pfeil J. Orthopädie. Stuttgart, Hippokrates Verlag, Duale Reihe, 1989.
2. Abatangelo G, O'Regan M. Hyaluronan: biological role and function in articular joints. Eur J Rheumatol Inflamm 1995;15:9-16.
3. Dahl LB, Dahl IM, Engstrom-Laurent A, Granath K. Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies. Ann Rheum Dis 1985;44:817-22.
4. Bragantini A, Cassini M, De Bastiani G, Perbellini A. Controlled single-blind trial of intra-articularly injected hyaluronate acid (Hyalgan) in osteoarthritis of the knee. Clin Tri J 1987;24:333-40.
5. Grecomoro G, Martomana C, Di Marco C. Intra-articular treatment with sodium hyaluronate in gonarthrosis: a controlled clinical trial versus placebo. Pharmatherapeutica 1987;5:137-41.
6. Dixon AS, Jacoby RK, Berry H, Hamilton EB. Clinical trial of intra-articular injection of sodium hyaluronate in patients with osteoarthritis of the knee. Curr Med Res Opin 1988;11:205-13.
7. Dougados M, Nguyen M, Listrat V, Amor B. High molecular weight sodium hyaluronate (Hyalectin) in osteoarthritis of the knee. A one-year placebo-controlled trial. Osteoarthritis Cartilage 1993;1:97-103.
8. Altman RD, Moskowitz R. Intra-articular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: a randomized clinical trial. Hyalgan Study Group. J Rheumatol 1998;25:2203-12.
9. Carraba M, Paresce E, Angelini M, Re KA, Torchiana EEM, Perbellini A. The safety and efficacy of different dose schedules of hyaluronic acid in the treatment of painful osteoarthritis of the knee with joint effusion. Eur J Rheumatol Inflamm 1995;15:25-31.
10. Huskisson EC, Donnelly S. Hyaluronic acid in the treatment of osteoarthritis of the knee. Rheumatology 1999;38: 602-7.
11. Leardini G, Franceschini M, Mattara L, Bruno R, Perbellini A. Intra-articular sodium hyaluronate (Hyalgan) in gonarthrosis. Clin Tri J 1987;24:341-50.
12. Jones A, Pattrick M, Doherty S, Doherty M. A double-blind trial of intra-articular hyaluronic acid (H.A.) versus triamcinolone hexacetonide (T.H.) in knee osteoarthritis (O.A.) (abstract). Arthritis Rheum 1992;335:S132.
13. Leardini G, Mattara L, Franceschini M, Perbellini A. Intra-articular treatment of knee osteoarthitis. A comparative study between hyaluronic acid and 6-methyl prednisolone acetate. Clin Exp Rheumatol 1991;9:375-81.
14. Pietrogrande V, Melanotte PL, D'Agnolo B, Ulivi M, Benigni GA, Turchetto L, et al. Hyaluronic acid versus methylprednisolone intra-articularly injected for treatment of osteoarthritis of the knee. Curr Ther Res 1991;50:691-701.
15. Grecomoro G, Piccione F, Letizia G. Therapeutic synergism between hyaluronic acid and dexamethasone in the intra-articular treatment of osteoarthritis of the knee: a preliminary open study. Curr Med Res Opin 1992;13:49-55.
16. Carraba M, Paresce E, Angelini M, Zamboni AM, Bragantini A, Pasissan A, et al. The intra-articular treatment of osteoarthritis of the knee. A comparative study between hyaluronic acid (Hyalgan) and Orgotein. Eur J Rheumatol Inflamm 1992;12:47-57.
17. Graf J, Neusel E, Schneider E, Niethard FU. Intra-articular treatment with hyaluronic acid in osteoarthritis of the knee joint: a controlled clinical trial versus mucopolysaccharide polysulfic acid ester. Clin Exp Rheumatol 1993;11:367-72.
18. Kolarz G, Kotz R, Bröll H, Dunky A, Landsiedl F, Mayrhofer F, et al. Hyaluronic acid in the treatment of osteoarthritis of the knee joint: interim results of a comparative clinical study. Eur J Rheumatol Inflamm 1995;15:39-45.
19. Kotz R, Kolarz G. Intra-articular hyaluronic acid: duration of effects and results of repeated treatment cycles. Am J Orthop 1999;28(suppl):5-7.
20. Kellgren J, Lawrence J. Atlas of Standard Radiographics: The Epidemiology of Chronic Rheumatism, vol 2. Oxford Blackwell Scientific Publications 1963.
21. Huskisson EC. Measurement of pain. Lancet 1974;2: 1127-31.
22. Larson RL. Rating sheet for knee function. In: Diseases of the Knee Joint, Smillie IA, ed. London. Churchill Livingstone 1974.
23. Watson MC, Brookes ST, Kirwan JR, Faulkner A. Non-aspirin, non-steroidal anti-inflammatory drugs for osteoarthritis of the knee (review). Cochrane Database Syst Rev 2000; CD000142.
24. Huskisson EC, Berry H, Gishen P, Jubb RW, Whitehead J. Effects of antiinflammatory drugs on the progression of osteoarthritis of the knee. J Rheumatol 1995;22:1941-6.
25. Henderson EB, Smith EC, Pegley F. Blake DR. Intra-articular injections of 750 KD hyaluronan in the treatment of osteoarthritis; a randomized single centre double-blind, placebo-controlled trial of 91 patients demonstrating lack of efficacy. Ann Rheum Dis 1994;53:529-34.
26. Dahlberg L, Lohmander LS, Ryd R. Intra-articular injections of hyaluronan in patients with cartilage abnormalities and knee pain. Arthritis Rheum 1994;37:521-8.