The effects of chronic ethanol consumption during early pregnancy on conceptus health and uterine function in pigs

Alcoholism: Clinical and Experimental Research

Volumn 27, Issue 4, 2003, Pages 712-719

  Kubotsu, Stephanie L ^a   Hu, Jianbo ^a,c   Carnahan, Kevin G ^b   DeAvila, Jeanene ^a   Ott, Troy L ^a,b   Mirando, Mark A ^a,d  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF IDAHO   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

^d U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

Conceptus; Endometrium; Ethanol; Pregnancy; Prostaglandin

Indexed keywords

ALCOHOL; DNA; GLUCOSE; PHOSPHOLIPASE C; PROSTAGLANDIN F2 ALPHA;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; AMNION FLUID; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALORIE; CONTROLLED STUDY; CORRELATION ANALYSIS; CROWN RUMP LENGTH; EMBRYO; ENDOMETRIUM; ESTRUS CYCLE; FEEDING; FEMALE; FERTILITY; FETUS; FETUS DEVELOPMENT; FETUS MORTALITY; FETUS WEIGHT; FIRST TRIMESTER PREGNANCY; HEALTH; HYSTERECTOMY; MATING; NONHUMAN; OVARY; PLACENTA WEIGHT; PREGNANCY; PRIORITY JOURNAL; SURVIVAL RATE; SWINE; UTERUS FUNCTION;

ANIMALIA; SUS SCROFA;

EID: 0037392262     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000062650.09584.2A     Document Type: Article

References (44)

1. Bazer FW, First NL (1983) Pregnancy and parturition. J Anim Sci (Suppl 2) 57:425-460.
2. 2α by the uterine endometrium. Prostaglandins 14:397-401.
3. Bocan TM (1998) Animal models of atherosclerosis and interpretation of drug intervention studies. Curr Pharm Des 4:37-52.
4. Burton K (1956) A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J 62:315-322.
5. Carey GB (1997) The swine as a model for studying exercise-induced changes in lipid metabolism. Med Sci Sports Exerc 29:1437-1443.
6. 2α in cyclic and early pregnant swine. Biol Reprod 55:838-843.
7. Cebral E, Lasserre A, Rettori V, de Gimeno MA (1997) Impaired mouse fertilization by low chronic alcohol treatment. Alcohol Alcohol 32:563-572.
8. Cebral E, Lasserre A, Rettori V, de Gimeno MA (2000) Alterations in preimplantation in vivo development after preconceptional chronic moderate alcohol consumption in female mice. Alcohol Alcohol 35:336-343.
9. Cebral E, Rettori V, de Gimeno MA (2001) Impact of chronic low-dose ethanol ingestion during sexual maturation of female mice on in-vitro and in-vivo embryo development. Reprod Toxicol 15:123-129.
10. Dexter JD, Tumbleson ME, Hutcheson DP, Middleton CC (1976) Sinclair (S-1) miniature swine as a model for the study of human alcoholism, work progress on alcoholism. Ann NY Acad Sci 273:188-193.
11. Dexter JD, Tumbleson ME, Decker JD, Middleton CC (1980) Fetal Alcohol Syndrome in Sinclair (S-1) Miniature Swine. Alcohol Clin Exper Res 4:146-151.
12. Dexter JD, Tumbleson ME, Decker JD, Middleton CC (1983) Comparison of the offspring of three serial pregnancies during voluntary alcohol consumption in Sinclair (S-1) miniature swine. Neurobehav Toxicol Teratol 5:229-231.
13. Fazakas-Todea I, Checiu M, Sandor S (1985) The effect of ethanol upon early development in mice and rats. VIII. The effect of chronic consumption of some beverages upon preimplantation development in rats. Morphol Embryol 31:249-256.
14. Flood PF (1991) The development of the conceptus and its relationship to the uterus. In: Reproduction in domestic animals, fourth ed., pp. 315-360, Cupps PT, ed., Academic Press Inc, San Diego, CA.
15. Gonzales RA, Crews FT (1988) Effects of ethanol in vivo and in vitro on stimulated phosphoinositide hydrolysis in rat cortex and cerebellum. Alcohol Clin Exper Res 12:94-98.
16. 14C: a radiographic study in monkeys and hamsters. Q J Stud Alcohol 33:485-493.
17. Hoek JB, Taraschi TF, Higashi K, Rubin E, Thomas AP (1990) Phospholipase C activation by ethanol in rat hepatocytes is unaffected by chronic ethanol feeding. Biochem J 272:59-64.
18. Jones AW, Hahn R, Stalberg HP (1992) Pharmacokinetics of ethanol in plasma and whole blood; Estimation of total body water by the dilution principle. Eur J Clin Pharmacol 42:445-448.
19. Jones PJH, Leichter J, Lee M (1981) Placental blood flow in rats fed alcohol before and during gestation. Life Sciences 29:1153-1159.
20. Kaufman MH, Wollam DHM (1981) The passage to the fetus and liquor amnii of ethanol administered orally to the pregnant mouse. Br J Exp Path 62:357-361.
21. Kivilaakso E, Ahonen J, Aronsen K-F, Hockerstedt K, Kalima T, Lempinen M, Vernerson E (1982) Gastric blood flow, tissue gas tension and microvascular changes during hemorrhage-induced stress ulceration in the pig. Am J Surg 143:322-330.
22. Kraeling RR, Rampacek GB, Fiorello NA (1985) Inhibition of pregnancy with indomethacin in mature gilts and prepubertal gilts induced to ovulate. Biol Reprod 32:105-110.
23. Lau IF, Saksena SK, Chang MC (1973) Pregnancy blockade by indomethacin, an inhibitor of prostaglandin synthesis: its reversal by prostaglandins and progesterone in mice. Prostaglandins 4:795-803.
24. Lee A (2000) Animal models of gastroduodenal ulcer disease. Baillieres Best Pract Res Clin Gastroenterol 14:75-96.
25. Ludwig TE, Sun BC, Carnahan KG, Uzumcu M, Yelich JV, Geisert RD, Mirando MA (1998) Endometrial responsiveness to oxytocin during diestrus and early pregnancy in pigs is not controlled solely by changes in oxytocin receptor population density. Biol Reprod 58:769-777.
26. Maier SE, Chen WA, Miller JA, West JR (1997) Fetal alcohol exposure and temporal vulnerability: regional differences in alcohol-induced microencephaly as a function of the timing of binge-like alcohol exposure during rat brain development. Alcohol Clin Exp Res 21:1418-1428.
27. Merritt AM, Brooks FP (1970) Basal and histamine-induced gastric secretion in the conscious miniature pig. Gastroenterology 58:801-814.
28. Mirando MA, Uzumcu M, Carnahan KG, Ludwig TE (1996) A role for oxytocin during luteolysis and early pregnancy in swine. Reprod Dom Anim 31:455-461.
29. NRC (1996) Nutrient Requirements of Swine. National Academy Press, Washington, DC.
30. Peters CA (2001) Animal models of fetal renal disease. Prenat Diagn 21:917-923.
31. Piano MR, Schwertz DW (1997) Effect of chronic ethanol exposure on myocardial phosphoinositide turnover. Alcohol Clin Exper Res 21:721-727.
32. Pope WF (1988) Uterine asynchrony: a cause of embryonic loss. Biol Reprod 39:999-1003.
33. Power JM, Tonkin AM (1999) Large animal models of heart failure. Aust N Z J Med 29:395-402.
34. Prince BC, Mirando MA, Becker WC, Hostetler CE (1995) Effect of exogenous oxytocin on interestrous interval of cyclic gilts. J Anim Sci 73:3681-3686.
35. Ramsey EM (1975) The placenta of laboratory animals and man. Holt, Rinehart and Winston, New York.
36. Reynolds JD, Penning DH, Kimura KA, Dexter F, Henderson JL, Atkins B, Poduska D, Brien JF (1997) Ethanol-induced changes in prostaglandin E concentration in the intact cerebral cortex of preterm and near-term fetal sheep. Alcohol Clin Exper Res 21:997-1004.
37. Statistical Analysis System (1996) PC-SAS Release 6.12, Cary, NC: Statistical Analysis System Institute, Inc.
38. Snedecor GW, Cochran WG (1980) Factorial experiments in Statistical Methods, 7th ed., pp 298-333. Iowa State University Press, Ames.
39. Steel RGD, Torrie JH (1980) Principles and Procedures of Statistics, A Biometrical Approach, 2nd ed. McGraw-Hill Book Co Inc, New York.
40. Sullivan TP, Eaglstein WH, Davis SC, Mertz P (2001) The pig as a model for human wound healing. Wound Repair Regen 9:66-76.
41. Tumbleson ME, Schook LB (1996) Advances in Swine in Biomedical Research. In: Advances in Swine in Biomedical Research, Vol 1:(Tumbleson ME, Schook LB, eds), pl. Plenum Press, New York.
42. 2α secretion by luminal epithelial, glandular epithelial and stromal cells from pig endometrium. II. Response of cyclic, pregnant and pseudopregnant pigs on days 12 and 16 post-oestrus. Reprod Fertil Devel 12:157-164.
43. Whiteaker SS, Mirando MA, Becker WC, Hostetler CE (1994) Detection of functional oxytocin receptors on endometrium of pigs. Biol Reprod 51:91-98.
44. Zhang JP, Xia JM, Sun GY (1997) Chronic ethanol inhibits inositol metabolism in specific brain regions. Alcohol Clin Exper Res 21:716-720.