Prospective evaluation of efficacy and toxicity of 5-FU and folinic acid (Mayo Clinic regimen) in patients with advanced cancer of the gallbladder

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 26, Issue 2, 2003, Pages 124-126

  Malik, Imtiaz A ^a   Aziz, Zeba ^b  

^a LOMA LINDA UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

5 Fluorouracil; Folinic acid; Gallbladder cancer; Mayo Clinic regimen

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

ABDOMINAL PAIN; ADENOCARCINOMA; ADULT; ADVANCED CANCER; ANEMIA; ANOREXIA; ARTICLE; ASTHENIA; CANCER GROWTH; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; DEATH; DIARRHEA; DRUG EFFICACY; FEBRILE NEUTROPENIA; FEMALE; GALLBLADDER CANCER; HUMAN; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; NEUTROPENIA; PROSPECTIVE STUDY; SHOCK; THROMBOCYTOPENIA; TREATMENT OUTCOME;

ADENOCARCINOMA; ANTIMETABOLITES, ANTINEOPLASTIC; FEMALE; FLUOROURACIL; GALLBLADDER NEOPLASMS; HUMANS; LEUCOVORIN; MALE; MIDDLE AGED; SURVIVAL ANALYSIS;

EID: 0037391166     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-200304000-00004     Document Type: Article

References (22)

1. Pitt HA, Grochow LB, Abrams RA. Cancer of the biliary tree. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: principles and practice of oncology. 5th ed. Philadelphia: Lippincott-Raven, 1997:1114-1128.
2. Falkson G, MacIntyre JM, Moertel CG. Eastern Cooperative Oncology Group experience with chemotherapy for inoperable gallbladder and bile duct cancer. Cancer 1984;54:965-969.
3. Davis HL Jr, Ramirez G, Ansfield FJ. Adenocarcinoma of stomach, pancreas, liver, and biliary tracts: survival of 328 patients treated with fluoropyrimidine therapy. Cancer 1974;33:193-197.
4. Haskell CM. Cancer of the liver. In: Haskell CM, ed. Cancer treatment. Philadelphia: WB Saunders, 1980:319-357.
5. Bukowski RM, Leichman LP, Rivkin SE. Phase II trial of m- ASMA in gallbladder and cholangiocarcinoma: a Southwest Oncology Group study. Eur J Cancer Clin Oncol 1983;6:721-723.
6. Jones DV, Lozano R, Hoque A, et al. Phase II study of paclitaxel therapy for unresectable biliary tree cancer. J Clin Oncol 1996;14:2306-2310.
7. Von Eyben F, Hellekant C, Mattson M, et al. Mitomycin-C in advanced gallbladder carcinoma. Acta Radiol 1980;19:81-84.
8. Crooke ST, Bradner WT. Mitomycin-C. A review. Cancer Treat Rev 1976;3:121-139.
9. Lersch C, Classen M. Palliative therapy of carcinomas of the biliary system. Med Klin 1997;92:401-405.
10. Cohen AM, Minsky BD, Schlisky RL. Cancer of the colon. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: principles and practice of Oncology. 5th ed. Philadelphia: Lippincott-Raven, 1997:1168-1197.
11. Miller HB, Hoogstraten B, Staguet M, et al. Reporting results of cancer treatment. Cancer 1981;47:207-214.
12. Ahmad M, Khan AH, Mansoor A. The pattern of malignant tumors in Northern Pakistan. J Pak Med Assoc 1991;41:270-273.
13. Patt YZ, Jones DV, Hoque A, et al. Phase II trial of intravenous fluorouracil and subcutaneous interferon alpha-2b for biliary tract cancer. J Clin Oncol 1996;14:2311-2315.
14. Gebbia V, Majello E, Testa A, et al. Treatment of advanced adenocarcinomas of the exocrine pancreas and the gallbladder with 5-fluorouracil, high dose levofolinic acid and oral hydroxyurea on a weekly schedule. Cancer 1996;78:1300-1307.
15. Chen JS, Jan YY, Lin YC, et al. Weekly 24 h infusion of high-dose 5-fluorouracil and leucovorin in patients with biliary tract carcinomas. Anticancer Drugs 1998;9:393-397.
16. Kato K, Koike A, Koide T, et al. Efficacy of 48-hour infusion of 5-fluorouracil for gallbladder cancer. Gan To Kagaku Ryoho 1993;20:2341-2344.
17. Mani S, Sciortino D, Samuels B, et al. Phase II trial of uracil/tegafur (UFT) plus leucovorin in patients with advanced biliary carcinoma. Invest New Drugs 1999;17:97-101.
18. st trial in non-resectable patients). Gan To Kagaku Ryoho 1992;19:1295-1301.
19. Hehenwarter W, Wein W, Schneider G, et al. Gemcitabine in cholangiocarcinoma: initially inoperable patient currently disease free. Ann Oncol 1996;7(suppl 5):53.
20. Castro MP. Efficacy of gemcitabine in the treatment of patients with gallbladder carcinoma. Cancer 1998;82:639-641.
21. Madajewics S, Hentschel P, Burns P, et al. Phase I chemotherapy study of biochemical modulation of folinic acid and fluorouracil by gemcitabine in patients with solid tumor malignancies. J Clin Oncol 2000;18:3553-3557.
22. Yamamoto S, Fujii K, Kitadai Y, et al. Expression of vascular endothelial growth factor in human gallbladder lesions. Oncol Rep 1998;5:1065-1069.