Mechanism of metal activation of human hematopoietic prostaglandin D synthase

Nature Structural Biology

Volumn 10, Issue 4, 2003, Pages 291-296

  Inoue, Tsuyoshi ^a,b   Irikura, Daisuke ^b   Okazaki, Nobuo ^a   Kinugasa, Shigehiro ^a   Matsumura, Hiroyoshi ^a   Uodome, Nobuko ^b   Yamamoto, Masaki ^c   Kumasaka, Takashi ^c,d   Miyano, Masashi ^c   Kai, Yasushi ^a   Urade, Yoshihiro ^b  

^a OSAKA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c RIKEN   (Japan)

^d TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; CALCIUM ION; GLUTATHIONE; GUANIDINE DERIVATIVE; HYDROGEN; MAGNESIUM ION; NITROGEN DERIVATIVE; PROSTAGLANDIN D SYNTHASE; PROSTAGLANDIN D2; PROSTAGLANDIN H2; PROTEIN SUBUNIT; WATER;

ALLERGY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CALCIUM TRANSPORT; CATALYSIS; CONCENTRATION RESPONSE; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVATION; ENZYME BINDING; ENZYME STRUCTURE; GLUTATHIONE METABOLISM; HEMATOPOIESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; ISOMERISM; MAGNESIUM METABOLISM; METAL BINDING; MOLECULAR DYNAMICS; NITROGEN METABOLISM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN INTERACTION; REDUCTION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; CALCIUM; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; ENZYME ACTIVATION; GLUTATHIONE; HEMATOPOIETIC SYSTEM; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; KINETICS; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0037389993     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb907     Document Type: Article

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