α2u-Globulin nephropathy and carcinogenicity following exposure to decalin (decahydronaphthalene) in F344/N rats

Toxicological Sciences

Volumn 72, Issue 2, 2003, Pages 223-234

  Dill, Jeffrey A ^a   Lee, Kyeonghee M ^a   Renne, Roger A ^a   Miller, Rodney A ^a   Fuciarelli, Alfred F ^a   Gideon, Kathy M ^a   Chan, Po C ^b   Burka, Leo T ^b   Roycroft, Joseph H ^b  

^a Toxicology Northwest   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

2u globulin; 2 decalone; Carcinogenicity; Cell proliferation; Decalin (decahydronaphthalene); Decalol; F344 N; Hyaline droplet; Hyperplasia; Nephropathy; Sex; Toxicity

Indexed keywords

2 DECALONE; ALPHA GLOBULIN; ALPHA2U GLOBULIN; CREATININE; CYCLINE; DECALIN; DECALOL; HYALIN; LACTATE DEHYDROGENASE; LIGAND; PROTEIN; SOLVENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CANCER INCIDENCE; CELL LABELING; CELL PROLIFERATION; CHRONIC KIDNEY DISEASE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE URINE LEVEL; CYTOPLASM; CYTOTOXICITY; DISEASE SEVERITY; DOSE RESPONSE; EPITHELIUM CELL; FEMALE; HISTOPATHOLOGY; KIDNEY ADENOMA; KIDNEY CARCINOMA; KIDNEY CORTEX; KIDNEY HOMOGENATE; KIDNEY MASS; KIDNEY PAPILLA; KIDNEY PROXIMAL TUBULE; MALE; MINERALIZATION; NONHUMAN; PELVIC DISEASE; RAT; SEX DIFFERENCE; URINALYSIS; URINARY EXCRETION; URINE LEVEL;

ADENOMA; ADMINISTRATION, INHALATION; ALPHA-GLOBULINS; ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; CARCINOMA; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYALIN; KIDNEY; KIDNEY NEOPLASMS; KIDNEY TUBULES, PROXIMAL; MALE; NAPHTHALENES; ORGAN SIZE; RATS; RATS, INBRED F344; SEX FACTORS; SOLVENTS;

ANIMALIA;

EID: 0037387724     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg028     Document Type: Article

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