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Volumn 73, Issue 4, 2003, Pages 304-311

Pharmacokinetics and pharmacodynamics of abarelix, a gonadotropin-releasing hormone antagonist, after subcutaneous continuous infusion in patients with prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

ABARELIX; ANDROSTANOLONE; FOLLITROPIN; GONADORELIN ANTAGONIST; LUTEINIZING HORMONE; PROSTATE SPECIFIC ANTIGEN; TESTOSTERONE;

EID: 0037385257     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(02)17637-5     Document Type: Article
Times cited : (16)

References (11)
  • 1
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    • Abarelix depot, a GnRH antagonist versus LHRH superagonists in prostate cancer: Differential effects on follicle-stimulating hormone
    • Garnick MB, Campion M. Abarelix depot, a GnRH antagonist versus LHRH superagonists in prostate cancer: differential effects on follicle-stimulating hormone. Mol Urol 2000;4:275-7.
    • (2000) Mol Urol , vol.4 , pp. 275-277
    • Garnick, M.B.1    Campion, M.2
  • 2
    • 0035516095 scopus 로고    scopus 로고
    • A phase 3, multiple, open-label, randomized study of abarelix versus leuprolide acetate in men with prostate cancer
    • McLeod D, Zinner N, Tomera K, et al. A phase 3, multiple, open-label, randomized study of abarelix versus leuprolide acetate in men with prostate cancer. Urology 2001;58:756-61.
    • (2001) Urology , vol.58 , pp. 756-761
    • McLeod, D.1    Zinner, N.2    Tomera, K.3
  • 3
    • 0035046991 scopus 로고    scopus 로고
    • The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin: Initial results of endocrinological and biochemical efficacies in patients with prostate cancer
    • Tomera K, Gleason D, Gittelman, et al. The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin: initial results of endocrinological and biochemical efficacies in patients with prostate cancer. J Urol 2001;165:1585-9.
    • (2001) J Urol , vol.165 , pp. 1585-1589
    • Tomera, K.1    Gleason, D.2    Gittelman3
  • 4
    • 0033668136 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone antagonists
    • Fluker MR. Gonadotropin-releasing hormone antagonists. Curr Opin Endocrinol Diabetes 2000;7:350-6.
    • (2000) Curr Opin Endocrinol Diabetes , vol.7 , pp. 350-356
    • Fluker, M.R.1
  • 5
    • 0033392782 scopus 로고    scopus 로고
    • LH-RH analogues: Their impact on reproductive medicine
    • Schally AV. LH-RH analogues: their impact on reproductive medicine. Gynecol Endocrinol 1999;13:401-9.
    • (1999) Gynecol Endocrinol , vol.13 , pp. 401-409
    • Schally, A.V.1
  • 6
    • 0028068645 scopus 로고
    • A single injection of a gonadotropin-releasing hormone (GnRH) antagonist (Cetrorelix) postpones the luteinizing hormone (LH) surge: Further evidence for the role of GnRH during the LH surge
    • Leroy I, d'Acremont M, Brailly-Tabard S, et al. A single injection of a gonadotropin-releasing hormone (GnRH) antagonist (Cetrorelix) postpones the luteinizing hormone (LH) surge: further evidence for the role of GnRH during the LH surge. Fertil Steril 1994;62:461-7.
    • (1994) Fertil Steril , vol.62 , pp. 461-467
    • Leroy, I.1    D'Acremont, M.2    Brailly-Tabard, S.3
  • 7
    • 0344405067 scopus 로고
    • Differential regulation of luteinizing hormone, follicle stimulating hormone, and the free alpha-subunit secretion from the gonadotrope by gonadotropin-releasing hormone (GnRH): Evidence from the use of two GnRH antagonists
    • Hall JE, Whitcomb RW, River JE, et al. Differential regulation of luteinizing hormone, follicle stimulating hormone, and the free alpha-subunit secretion from the gonadotrope by gonadotropin-releasing hormone (GnRH): evidence from the use of two GnRH antagonists. J Clin Endocrinol Metab 1992;75:1220-5.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1220-1225
    • Hall, J.E.1    Whitcomb, R.W.2    River, J.E.3
  • 8
    • 0028314613 scopus 로고
    • Contrasting effects of a gonadotropin-releasing hormone agonist and antagonist on the secretion of free alpha subunit
    • Fluker MR, Monroe SE, Marshall LA, et al. Contrasting effects of a gonadotropin-releasing hormone agonist and antagonist on the secretion of free alpha subunit. Fertil Steril 1994;61:573-5.
    • (1994) Fertil Steril , vol.61 , pp. 573-575
    • Fluker, M.R.1    Monroe, S.E.2    Marshall, L.A.3
  • 9
    • 0344836716 scopus 로고    scopus 로고
    • A novel depot formulation extended the intramuscular delivery of abarelix, a GnRH antagonist in healthy men age 50-75
    • 2001 Oct 21-25; Denver, Colo. Denver: The Association
    • Wong SL, Lau DT-W, Baughman SA, et al. A novel depot formulation extended the intramuscular delivery of abarelix, a GnRH antagonist in healthy men age 50-75 [abstract]. In: Proceedings of the 2001 Annual American Association of Pharmaceutical Scientists Meeting; 2001 Oct 21-25; Denver, Colo. Denver: The Association; 2001.
    • (2001) Proceedings of the 2001 Annual American Association of Pharmaceutical Scientists Meeting
    • Wong, S.L.1    Lau, D.T.-W.2    Baughman, S.A.3
  • 10
    • 0031689757 scopus 로고    scopus 로고
    • Single and multiple dose pharmacokinetics and pharmacodynamics of the gonadotropin-releasing hormone antagonist Cetrorelix in healthy female volunteers
    • Duijkers LJM, Klipping C, Willemsen WNP, et al. Single and multiple dose pharmacokinetics and pharmacodynamics of the gonadotropin-releasing hormone antagonist Cetrorelix in healthy female volunteers. Hum Reprod 1998;13:2392-8.
    • (1998) Hum Reprod , vol.13 , pp. 2392-2398
    • Duijkers, L.J.M.1    Klipping, C.2    Willemsen, W.N.P.3
  • 11
    • 0345699632 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic (PK/PD) modeling of the hormonal suppression characteristics of abarelix delivered by a novel depot formulation
    • 2001 Oct 21-25; Denver, Colo. Denver: The Association
    • Wong SL, Lau DT-W, Baughman SA, et al. Pharmacokinetic/pharmacodynamic (PK/PD) modeling of the hormonal suppression characteristics of abarelix delivered by a novel depot formulation [abstract]. In: Proceedings of the 2001 Annual American Association of Pharmaceutical Scientists Meeting; 2001 Oct 21-25; Denver, Colo. Denver: The Association; 2001.
    • (2001) Proceedings of the 2001 Annual American Association of Pharmaceutical Scientists Meeting
    • Wong, S.L.1    Lau, D.T.-W.2    Baughman, S.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.