메뉴 건너뛰기




Volumn 48, Issue 4, 2003, Pages 790-796

Effect of protein kinase C activation and inhibition on rat hepatic stellate cell activation

Author keywords

smooth muscle actin; Fibrosis; Hepatic stellate cells; Liver; Proliferation; Protein kinase C

Indexed keywords

ACTIN; BISINDOLYLMALEIMIDE; CHELERYTHRINE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; STAUROSPORINE; THYMELEATOXIN; UNCLASSIFIED DRUG;

EID: 0037382326     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022857313917     Document Type: Article
Times cited : (12)

References (46)
  • 1
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular response
    • Nishizuka Y: Protein kinase C and lipid signaling for sustained cellular response. FASEB J 9:484-496, 1995
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 2
    • 0028260497 scopus 로고
    • Lipid mediators and protein kinase C activation for the intracellular signaling network
    • Nakamura S, Nishizuka Y: Lipid mediators and protein kinase C activation for the intracellular signaling network. Biochem J 115:1029-1034, 1994
    • (1994) Biochem J , vol.115 , pp. 1029-1034
    • Nakamura, S.1    Nishizuka, Y.2
  • 3
    • 0027104825 scopus 로고
    • The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation
    • Clemens MJ, Trayner I, Menaya J: The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation. J Cell Sci 103:881-887, 1992
    • (1992) J Cell Sci , vol.103 , pp. 881-887
    • Clemens, M.J.1    Trayner, I.2    Menaya, J.3
  • 4
    • 0021443856 scopus 로고
    • Inositol triphosphate and diacylglycerol as second messengers
    • Berridge MJ: Inositol triphosphate and diacylglycerol as second messengers. Biochem J 220:345-360, 1984
    • (1984) Biochem J , vol.220 , pp. 345-360
    • Berridge, M.J.1
  • 5
    • 0020326790 scopus 로고
    • Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters
    • Catagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U, Nishizuka Y: Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem 257:7847-7851, 1982
    • (1982) J Biol Chem , vol.257 , pp. 7847-7851
    • Catagna, M.1    Takai, Y.2    Kaibuchi, K.3    Sano, K.4    Kikkawa, U.5    Nishizuka, Y.6
  • 6
    • 0020698115 scopus 로고
    • 2+, phospholipid-dependent protein kinase associated with plasma membrane
    • 2+, phospholipid-dependent protein kinase associated with plasma membrane. Nature 301:621-623, 1983
    • (1983) Nature , vol.301 , pp. 621-623
    • Kraft, A.S.1    Anderson, W.B.2
  • 7
    • 0021288161 scopus 로고
    • 2+-sensitive, phospholipid-dependent protein kinase activity in phorbolester-treated 3T3 cells
    • 2+-sensitive, phospholipid-dependent protein kinase activity in phorbolester-treated 3T3 cells. Biochem Biophys Res Commun 120:1053-1059, 1984
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 1053-1059
    • Rodriguez-Pena, A.1    Rozengurt, E.2
  • 8
    • 0025734994 scopus 로고
    • Perisinusoidal stellate cell of the liver: Important roles in retinol metabolism and fibrosis
    • Blomhoff R, Wake K: Perisinusoidal stellate cell of the liver: important roles in retinol metabolism and fibrosis. FASEB J 5:271-277, 1991
    • (1991) FASEB J , vol.5 , pp. 271-277
    • Blomhoff, R.1    Wake, K.2
  • 10
    • 0026846805 scopus 로고
    • Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture
    • Rockey DC, Boyles JK, Gabbiani G, Friedman SL: Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture. J Submicrosc Cytol Pathol 24:193-203, 1992
    • (1992) J Submicrosc Cytol Pathol , vol.24 , pp. 193-203
    • Rockey, D.C.1    Boyles, J.K.2    Gabbiani, G.3    Friedman, S.L.4
  • 11
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • Friedman SL: The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 328:1828-1835, 1993
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 12
    • 0029026661 scopus 로고
    • Cytokines and cellular crosstalk involved in the activation of fat-storing cells
    • Gressner AM: Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J Hepatol 22(suppl 2):28-36, 1995
    • (1995) J Hepatol , vol.22 , Issue.SUPPL. 2 , pp. 28-36
    • Gressner, A.M.1
  • 13
    • 0025990476 scopus 로고
    • Tissue distribution, quantitation and proliferation kinetics of fat-storing cells in carbon tetrachloride-injured rat liver
    • Geerts A, Lazou JM, DeBleser P, Wisse E: Tissue distribution, quantitation and proliferation kinetics of fat-storing cells in carbon tetrachloride-injured rat liver. Hepatology 13:1193-1202, 1991
    • (1991) Hepatology , vol.13 , pp. 1193-1202
    • Geerts, A.1    Lazou, J.M.2    DeBleser, P.3    Wisse, E.4
  • 14
    • 0020579923 scopus 로고
    • The role of fat-storing cells in Disse space fibrogenesis in alcoholic liver disease
    • Minato Y, Hasumura Y, Takeuchi J: The role of fat-storing cells in Disse space fibrogenesis in alcoholic liver disease. Hepatology 3:559-566, 1983
    • (1983) Hepatology , vol.3 , pp. 559-566
    • Minato, Y.1    Hasumura, Y.2    Takeuchi, J.3
  • 15
    • 0344283735 scopus 로고
    • Protein kinase in rat lipocytes
    • E Wisse, DL Knook, K Wake (eds). Leiden, Kupffer Cell Foundation
    • Kobayashi Y, Britton RS, Ramm GA, O'Neill R, Bacon BR: Protein kinase in rat lipocytes. In Cells of the Hepatic Sinusoid, Vol 5: E Wisse, DL Knook, K Wake (eds). Leiden, Kupffer Cell Foundation, 1995 pp 351-353
    • (1995) Cells of the Hepatic Sinusoid , vol.5 , pp. 351-353
    • Kobayashi, Y.1    Britton, R.S.2    Ramm, G.A.3    O'Neill, R.4    Bacon, B.R.5
  • 16
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark EA, Brugge J: Integrins and signal transduction pathways: The road taken. Science 268:233-239, 1995
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.2
  • 17
    • 0024840085 scopus 로고
    • Effect of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells
    • Pinzani M, Gesualdo L, Subbah GM, Abboud HE: Effect of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells. J Clin Invest 84:1786-1793, 1989
    • (1989) J Clin Invest , vol.84 , pp. 1786-1793
    • Pinzani, M.1    Gesualdo, L.2    Subbah, G.M.3    Abboud, H.E.4
  • 18
    • 4243386157 scopus 로고
    • Platelet-derived growth factor activates protein kinase C in rat hepatic lipocytes
    • abstract
    • Kobayashi Y, Britton RS, O'Neill R, Bacon BR: Platelet-derived growth factor activates protein kinase C in rat hepatic lipocytes. Hepatology 18:168A, 1993 (abstract)
    • (1993) Hepatology , vol.18
    • Kobayashi, Y.1    Britton, R.S.2    O'Neill, R.3    Bacon, B.R.4
  • 19
    • 0028338934 scopus 로고
    • Identification and characterization of a receptor for tissue ferritin on activated lipocytes
    • Ramm GA, Britton RS, O'Neill R, Bacon BR: Identification and characterization of a receptor for tissue ferritin on activated lipocytes. J Clin Invest 94:9-15, 1994
    • (1994) J Clin Invest , vol.94 , pp. 9-15
    • Ramm, G.A.1    Britton, R.S.2    O'Neill, R.3    Bacon, B.R.4
  • 20
    • 0023113248 scopus 로고
    • Isolation and culture of hepatic lipocytes. Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan
    • Friedman SL, Roll FJ: Isolation and culture of hepatic lipocytes. Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan. Anal Biochem 161:207-218, 1987
    • (1987) Anal Biochem , vol.161 , pp. 207-218
    • Friedman, S.L.1    Roll, F.J.2
  • 23
    • 0027404472 scopus 로고
    • In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury
    • Hines JE, Johnson SJ, Burt AD: In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury. Am J Pathol 142:511-518, 1993
    • (1993) Am J Pathol , vol.142 , pp. 511-518
    • Hines, J.E.1    Johnson, S.J.2    Burt, A.D.3
  • 24
    • 0025000652 scopus 로고
    • Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo
    • Maher JJ, McGuire RF: Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest 86:1641-1648, 1990
    • (1990) J Clin Invest , vol.86 , pp. 1641-1648
    • Maher, J.J.1    McGuire, R.F.2
  • 25
    • 0031878097 scopus 로고    scopus 로고
    • Contribution of hepatic parenchymal and non-parenchymal cells to hepatic fibrogenesis in biliary atresia
    • Ramm GA, Nair VG, Bridle KR, Shepherd RW, Crawford DHG: Contribution of hepatic parenchymal and non-parenchymal cells to hepatic fibrogenesis in biliary atresia. Am J Pathol 153:527-535, 1998
    • (1998) Am J Pathol , vol.153 , pp. 527-535
    • Ramm, G.A.1    Nair, V.G.2    Bridle, K.R.3    Shepherd, R.W.4    Crawford, D.H.G.5
  • 27
    • 0033810010 scopus 로고    scopus 로고
    • The morphology of liver repair following cholestatic liver injury: Resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts
    • Ramm GA, Carr SC, Bridle KR, Li L, Crawford DHG, Vogler CA, Britton RS, Bacon BR, Tracy TF Jr: The morphology of liver repair following cholestatic liver injury: resolution of ductal hyperplasia, matrix deposition and regression of myofibroblasts. Liver 20:387-396, 2000
    • (2000) Liver , vol.20 , pp. 387-396
    • Ramm, G.A.1    Carr, S.C.2    Bridle, K.R.3    Li, L.4    Crawford, D.H.G.5    Vogler, C.A.6    Britton, R.S.7    Bacon, B.R.8    Tracy T.F., Jr.9
  • 28
    • 0027366398 scopus 로고
    • Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo
    • Rockey DC, Housset CN, Friedman SL: Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo. J Clin Invest 92:1795-1804, 1993
    • (1993) J Clin Invest , vol.92 , pp. 1795-1804
    • Rockey, D.C.1    Housset, C.N.2    Friedman, S.L.3
  • 30
    • 0031054425 scopus 로고    scopus 로고
    • Hepatic stellate cell activation in genetic hemochromatosis: Lobular distribution, effect of increasing hepatic iron and response to phlebotomy
    • Ramm GA, Crawford DHG, Powell LW, Walker NI, Fletcher LM, Halliday JW: Hepatic stellate cell activation in genetic hemochromatosis: lobular distribution, effect of increasing hepatic iron and response to phlebotomy. J Hepatol 26:584-592, 1997
    • (1997) J Hepatol , vol.26 , pp. 584-592
    • Ramm, G.A.1    Crawford, D.H.G.2    Powell, L.W.3    Walker, N.I.4    Fletcher, L.M.5    Halliday, J.W.6
  • 31
    • 0028596335 scopus 로고
    • Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis
    • Jarnagin WR, Rockey DC, Koteliansky VE, Wang SS, Bissell DM: Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol 127:2037-2048, 1994
    • (1994) J Cell Biol , vol.127 , pp. 2037-2048
    • Jarnagin, W.R.1    Rockey, D.C.2    Koteliansky, V.E.3    Wang, S.S.4    Bissell, D.M.5
  • 32
    • 0028838193 scopus 로고
    • Activation of hepatic stellate cells by TGFα and collagen type I is mediated by oxidative stress through c-myb expression
    • Lee KS, Buck M, Houglum K, Chojkier M: Activation of hepatic stellate cells by TGFα and collagen type I is mediated by oxidative stress through c-myb expression. J Clin Invest 96:2461-2468, 1995
    • (1995) J Clin Invest , vol.96 , pp. 2461-2468
    • Lee, K.S.1    Buck, M.2    Houglum, K.3    Chojkier, M.4
  • 33
    • 0028170153 scopus 로고
    • Induction of B-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
    • Wong L, Yamasaki G, Johnson RJ, Friedman SL: Induction of B-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture. J Clin Invest 94:1563-1569, 1994
    • (1994) J Clin Invest , vol.94 , pp. 1563-1569
    • Wong, L.1    Yamasaki, G.2    Johnson, R.J.3    Friedman, S.L.4
  • 36
    • 0024394417 scopus 로고
    • Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases
    • Ruegg UT, Burgess GM: Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases. Trends Pharmacol Sci 10:218-220, 1989
    • (1989) Trends Pharmacol Sci , vol.10 , pp. 218-220
    • Ruegg, U.T.1    Burgess, G.M.2
  • 38
    • 0344715747 scopus 로고
    • Regulation of protein kinase C isoforms in rat hepatic lipocytes
    • abstract
    • Kobayashi Y, Britton RS, O'Neill R, Bacon BR: Regulation of protein kinase C isoforms in rat hepatic lipocytes. Gastroenterology 104:A929, 1993 (abstract)
    • (1993) Gastroenterology , vol.104
    • Kobayashi, Y.1    Britton, R.S.2    O'Neill, R.3    Bacon, B.R.4
  • 39
    • 0023025201 scopus 로고
    • Early signals in the mitogenic response
    • Rozengurt E: Early signals in the mitogenic response. Science 234:161-166, 1986
    • (1986) Science , vol.234 , pp. 161-166
    • Rozengurt, E.1
  • 40
    • 0023108159 scopus 로고
    • Possible involvement of protein kinase C in platelet-derived growth factor-stimulated DNA synthesis in vascular smooth muscle cells
    • Kariya K, Kawahara Y, Tsuda T, Fukuzaki H, Takai Y: Possible involvement of protein kinase C in platelet-derived growth factor-stimulated DNA synthesis in vascular smooth muscle cells. Atherosclerosis 63:251-255, 1987
    • (1987) Atherosclerosis , vol.63 , pp. 251-255
    • Kariya, K.1    Kawahara, Y.2    Tsuda, T.3    Fukuzaki, H.4    Takai, Y.5
  • 41
    • 0025729730 scopus 로고
    • Role of Raf-1 serine/threonine protein kinase in growth factor signal transduction
    • Rapp UR: Role of Raf-1 serine/threonine protein kinase in growth factor signal transduction. Oncogene 6:495-500, 1991
    • (1991) Oncogene , vol.6 , pp. 495-500
    • Rapp, U.R.1
  • 42
    • 0028356362 scopus 로고
    • Prostaglandin E suppression of platelet-derived-growth-factor-induced Ito cell mitogenesis occurs independent of raf perinuclear translocation and nuclear protooncogene expression
    • Beno DWA, Rapp UR, Davis BH: Prostaglandin E suppression of platelet-derived-growth-factor-induced Ito cell mitogenesis occurs independent of raf perinuclear translocation and nuclear protooncogene expression. Biochim Biophys Acta 1222:292-300, 1994
    • (1994) Biochim Biophys Acta , vol.1222 , pp. 292-300
    • Beno, D.W.A.1    Rapp, U.R.2    Davis, B.H.3
  • 43
    • 0027331512 scopus 로고
    • 3 activates Raf kinase and Raf perinuclear translocation via a protein kinase C-dependent pathway
    • 3 activates Raf kinase and Raf perinuclear translocation via a protein kinase C-dependent pathway. J Biol Chem 268:25132-25138, 1993
    • (1993) J Biol Chem , vol.268 , pp. 25132-25138
    • Lissoos, T.W.1    Beno, D.W.A.2    Davis, B.H.3
  • 46
    • 0026543287 scopus 로고
    • Elements of the smooth muscle α-actin promoter required in cis for transcriptional activation in smooth muscle. Evidence for cell-type specific regulation
    • Blank RS, McQuinn TC, Yin KC, Thompson MM, Takeyasu K, Schwartz RJ, Owens GK: Elements of the smooth muscle α-actin promoter required in cis for transcriptional activation in smooth muscle. Evidence for cell-type specific regulation. J Biol Chem 267:984-989, 1992
    • (1992) J Biol Chem , vol.267 , pp. 984-989
    • Blank, R.S.1    McQuinn, T.C.2    Yin, K.C.3    Thompson, M.M.4    Takeyasu, K.5    Schwartz, R.J.6    Owens, G.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.