p18(INK4c) collaborates with other CDK-inhibitory proteins in the regenerating liver

Hepatology

Volumn 37, Issue 4, 2003, Pages 833-841

  Luedde, Tom ^a   Rodriguez, Maria E ^b   Tacke, Frank ^a   Xiong, Yue ^b   Brenner, David A ^c   Trautwein, Christian ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; MUTANT PROTEIN; PROTEIN P18; PROTEIN P21; PROTEIN P27; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL CYCLE G1 PHASE; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; KNOCKOUT MOUSE; LIVER CELL; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WILD TYPE;

EID: 0037381639     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2003.50136     Document Type: Article

References (40)

1. Higgins GM, Anderson RM. Experimental pathology of liver. I. Restoration of liver of white rat following partial surgical removal. Arch Pathol 1931;12:186-202.
2. Michalopoulos GK, DeFrances M. Liver regeneration. Science 1997;276:60-66.
3. Fausto N. Liver regeneration. J Hepatol 2000;32(Suppl):19-31.
4. Streetz KL, Luedde T, Manns MP, Trautwein C. Interleukin 6 and liver regeneration. Gut 2000;47:309-312.
5. Morgan DO. Principles of CDK regulation. Nature 1995;374:131-134.
6. Wuarin J, Nurse P. Regulating S phase: CDKs, licensing and proteolysis. Cell 1996;85:785-787.
7. Matsushime H, Quelle DE, Shurtleff SA, Shibuya M, Sherr CJ, Kato JY. D-type cyclin-dependent kinase activity in mammalian cells. Mol Cell Biol 1994;14:2066-2076.
8. 1 phase. Biochem J 1997;326:61-68.
9. Cheng M, Sexl V, Sherr CJ, Roussel MF. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc Natl Acad Sci U S A 1998;95:1091-1096.
10. Nevins JR. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 1992;258:424-429.
11. Ohtsubo M, Theodoras AM, Schumacher J, Roberts J, Pagano M. Human cyclin E, a nuclear protein essential for the G1 to S phase transition. Mol Cell Biol 1995;15:2612-2624.
12. Pagano M, Pepperkok R, Lukas J, Ansorge W, Bartek J, Draetta G. Regulation of the cell-cycle by the cdk2 protein kinase in cultured human fibroblasts. J Cell Biol 1992;121:101-111.
13. Sclafani RA. Cyclin dependent kinase activating kinases. Curr Opin Cell Biol 1996;8:788-794.
14. Sherr CH, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999;13:1501-1512.
15. Sherr CH, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995;9:1149-1163.
16. Harper JW, Elledge SJ. Cdk inhibitors in development and cancer. Curr Opin Gen Dev 1996;6:56-64.
17. Guan KL, Jenkins CW, Li Y, Nichols MA, Wu X, O'Keefe CL, Matera AG, et al. Growth suppression by p18, a p16INK4/MTS1a and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev 1994;8:2939-2952.
18. INK4c expression during myogenesis. Mol Cell Biol 1998;18:2334-2343.
19. Franklin DS, Xiong Y. Induction of p18INK4c and its predominant association with CDK4 and CDK6 during myogenic differentiation. Mol Biol Cell 1996;7:1587-1599.
20. Zindy F, Soares H, Herzog KH, Morgan J, Sherr CH, Roussel MF. Expression of INK4 inhibitor of cyclin D-dependent kinases during brain development. Cell Growth Differ 1997;8:1139-1150.
21. Zindy F, Quelle DE, Roussel MF, Sherr CJ. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene 1997;15:203-211.
22. KIP1 mediate two separate pathways to collaboratively suppress pituitary tumorigenesis. Genes Dev 1998;12:2899-2911.
23. Albtecht HA, Poon RYC, Ahonen CL, Rieland BM, Deng C, Crary G. Involvement of p21 and p27 in the regulation of CDK activity and cellcycle-progression in the regenerating liver. Oncogene 1998;16:2141-2150.
24. Ctary GS, Albrecht JH. Expression of cyclin-dependent kinase inhibitor p21 in human liver. HEPATOLOGY 1998;28:738-743.
25. Qin LF, Oi-Lin NG. Expression of p27KIP1 and p21WAF1/CIP1 in primary hepatocellular carcinoma: clinicopathologic correlation and survival analysis. Hum Pathol 2001;32:778-784.
26. Tannapfel A, Grund D, Katalinic A, Uhlmann D, Knöckerling F, Haugwitz U, Wasner M, et al. Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma. Int J Cancer 2000; 89:350-355.
27. Deng C, Zhang P, Harper JW, Elledge SJ, Leder P. Mice lacking p21 CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995;82:675-684.
28. Kip1. Cell 1996;85:721-732.
29. Ludde T, Kubicka S, Plumpe J, Liedtke C, Manns MP, Trautwein C. Ras adenoviruses modulate cyclin E protein expression and DNA synthesis after partial hepatectomy. Oncogene 2001;20:5264-5278.
30. Jenkins CW, Xiong Y. Immunoprecipitation and immunoblotting in cellcycle studies. In: Pagano M, ed. Cell-Cycle: Material and Methods. New York: Springer-Verlag, 1995:250-263.
31. Nelsen CJ, Rickheim DG, Timchenko NA, Stanley MW, Albrecht JH. Transient expression of cyclin D1 is sufficient to promote hepatocyte replication and liver growth in vivo. Cancer Res 2001;61:8564-8568.
32. Grafstrom RH, Pan W, Hoess RH. Defining the substrate specificity of CDK4 kinase-cyclin D1 complex. Carcinogenesis (Lond) 1999;20:193-198.
33. Karnezis AN, Dorokhov M, Grompe M, Zhu L. Loss of p27Kip1 enhances the transplantation efficiency of hepatocytes transferred into diseased livers. J Clin Invest 2001;108:383-390.
34. Paulsen JE. Variations in regenerative growth of mouse liver following partial hepatectomy. In Vivo 1990;4:235-238.
35. Tsukamoto I, Kojo S. The sex difference in the regulation of liver regeneration after partial hepatectomy in the rat. Biochim Biophys Acta 1990; 1033:287-290.
36. Cuenca AG, Cress WD, Good RA, Marikar Y, Engelmann RW. Calorie restriction influences cell cycle progression and DNA synthesis during liver regeneration. Exp Biol Med 2001;226:1061-1067.
37. Franklin DS, Godfrey VL, O'Brien DA, Deng C, Xiong Y. Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity. Mol Cell Biol 2000; 20:6147-6158.
38. Awad MM, Sanders JA, Gruppuso PA. A potential role for p15INK4b and p57Kip2 in livet development. FEBS Lett 2000;483:160-164.
39. Zezula J, Cassaccia-Bonnefil P, Ezhevsky SA, Ostethout DJ, Levine JM, Dowdy SF, Chao MV, et al. p21(cip 1) is required for the differentiation of oligodendtocytes independently of cell-cycle withdrawal. EMBO Rep 2001;2:27-34.
40. Cheng T, Scadden DT. Cell-cycle entry of hematopoietic stem and progenitor cells controlled by distinct cyclin-dependent kinase inhibitors. Int J Hematol 2002;75:460-465.