Effects of Ghrelin on growth hormone secretion from cultured adenohypophysial cells in pigs

Domestic Animal Endocrinology

Volumn 24, Issue 3, 2003, Pages 209-218

  Hashizume, T ^a   Horiuchi, M ^a   Tate, N ^a   Nonaka, S ^a   Mikami, U ^a   Kojima, M ^b  

^a IWATE UNIVERSITY   (Japan)

^b KURUME UNIVERSITY   (Japan)

Author keywords

GH; Ghrelin; GHRH; Pig; Somatostatin

Indexed keywords

SUIDAE; SUS SCROFA;

EID: 0037381478     PISSN: 07397240     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0739-7240(02)00240-0     Document Type: Article

References (29)

1. Bowers CY. Growth hormone-releasing peptide (GHRP). Cell Mol Life Sci 1998;54:1316-29.
2. Smith RG, Van der Ploeg LHT, Howard AD, Feighner SD, Cheng K, Hickey GJ, et al. Peptidomimetic regulation of growth hormone secretion. Endocr Rev 1997;18:621-45.
3. Smith RG, Cheng K, Schoen WR, Pong S-S, Hickey G, Jacks T, Butler B, et al. A nonpeptidyl growth hormone secretagogue. Science 1993;260:1640-3.
4. Howard AD, Freighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 1996;273:974-7.
5. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999;402:656-61.
6. Date Y, Murakami N, Kojima M, Kuroiwa T, Matsukura S, Kangawa K, et al. Central effects of a novel acylated peptide, ghrelin, on growth hormone release in rats. Biochem Biophys Res Common 2000;275:477-80.
7. Seoane LM, Tovar S, Baldelli R, Arvat E, Ghigo E, Casnueva FF, et al. Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats. Eur J Endocrinol 2000;143:R7-9.
8. Tolle V, Zizzari P, Tomasetto C, Rio MC, Epelbaum J, Bluet-Pajot MT. In vivo and in vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in the rat. Neuroendocrinology 2001;73:54-61.
9. Yamazaki M, Nakamura K, Kobayashi H, Matsubara M, Hayashi Y, Kangawa K, et al. Regulational effect of ghrelin on growth hormone secretion from perifused rat anterior pituitary cells. J Neuroendocrinol 2002;14:156-62.
10. Arvat E, Di Vito L, Broglio F, Papotti M, Muccioli G, Dieguez C, et al. Preliminary evidence that ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans. J Endocrinol Invest 2000;23:493-5.
11. Peino R, Baldelli R, Rodriguz-Garcia J, Rodriguez-Segade S, Kojima M, Kangawa K, et al. Ghrelin-induced growth hormone secretion in humans. Eur J Endocrinol 2000;143:R11-4.
12. Takaya K, Ariyasu H, Kanamoto N, Iwakura H, Yoshimoto A, Harada M, et al. Ghrelin strongly stimulates growth hormone (GH) release in humans. J Clin Endocrinol Metab 2000;85:4908-11.
13. Arvat E, Maccario M, Di Vito L, Broglio F, Benso A, Gottero C, et al. Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a non-natural peptidyl GHS, and GH-releasing hormone. J Clin Endocrinol Metab 2001;86:1169-74.
14. Di Vito L, Broglio F, Benso A, Gottero C, Prodam F, Papotti, M, et al. The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans. Clin Endocrinol (Oxf) 2002;56:643-8.
15. Hataya Y, Akamizu T, Takaya K, Kanamoto N, Ariyasu H, Saijo M, et al. A low dose of ghrelin stimulates growth hormone (GH) release synergistically with GH-releasing hormone in humans. J Clin Endocrinol Metab 2001;86:4552.
16. Hayashida T, Murakami K, Mogi K, Nishihara M, Nakazato M, Mondal M, et al. Ghrelin in domestic animals: distribution in stomach and its possible role. Domest Anim Endocrinol 2001;21:17-24.
17. Frohman LA, Bowns TR, Chomcznski P. Regulation of growth hormone secretion. Front Neuroendocrinol 1992;13:344-405.
18. Hashizume T, Soliman EB, Kanematsu S. Effects of pituitary adenylate cyclase-activating polypeptide (PACAP), prostaglandin E (PG) and growth hormone releasing factor (GRF) on the release of growth hormone from cultured bovine anterior pituitary cells in vitro. Domest Anim Endocrinol 1994;11:331-7.
19. Johke T. Effects of TRH on circulating growth hormone, prolatin and triiodothyronine levels in the bovine. Endocrinol Jpn 1978;25:19-26.
20. Dieguez C, Casanueva FF. Ghrelin: a step forward in the understanding of somatotroph cell function and growth regulation. Eur J Endocrinol 2000;142:413-7.
21. 2 on growth hormone (GH)-releasing factor-stimulated GH release and intracellular adenosine 3′,5′-monophosphate accumulation in rat primary pituitary cell culture. Endocrinology 1989;124:2791-8.
22. Bowers CY, Sartor AO, Reynoldes GA, Badger TM. On the actions of the growth hormone-releasing hexapeptides, GHRP. Endocrinology 1991;128:2027-35.
23. Hickey GJ, Drisko J, Faidley T, Chang C, Anderson LL, Nicolich S, et al. Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585. J Endocrinol 1996;148:371-80.
24. Wu D, Chen C, Katoh K, Zhang J, Clarke IJ. The effect of GH-releasing peptide-2 (GHRP-2 or KP102) on GH secretion from primary cultured ovine pituitary cells can be abolished by a specific GH-releasing factor (GRF) receptor antagonist. J Endocrinol 1994;140:R9-13.
25. Hashizume T, Yanagimoto M, Kainuma S, Nagano R, Moriwaki K, Ohtsuki K, et al. Effects of new growth hormone-releasing peptide (KP102) on the release of growth hormone in vitro and in vivo in cattle. Anim Sci Technol (Jpn) 1997;68:450-8.
26. Locatelli V, Torsello A. Growth hormone secretagogues: focus on the growth hormone-releasing peptides. Pharm Res 1997;36:415-23.
27. Wren AM, Small CJ, Word HL, Murphy KG, Dakin CL, Taheri S, et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretions. Endocrinology 2000;141:4325-8.
28. Tschop MS, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 2000;407:908-13.
29. Nakazato M, Murakami N, Date Y, Kojima K, Matsuo H, Kangawa K, et al. A role for ghrelin in the central regulation of feeding. Nature 2001;409:194-8.