Subcutaneous versus intramuscular administration of human chorionic gonadotropin during an in vitro fertilization cycle

Fertility and Sterility

Volumn 79, Issue 4, 2003, Pages 881-885

  Stelling, James R ^a,b,c,d   Chapman, Emily T ^a,d   Frankfurter, David ^a,c,e   Harris, Doria H ^a,c   Oskowitz, Selwyn P ^a,c   Reindollar, Richard H ^a,c  

^a BOSTON IVF   (United States)

^b Building 19   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d Reproductive Science Associates   (United States)

^e BROWN UNIVERSITY   (United States)

Author keywords

Follicular fluid; hCG; Intramuscular; Pharmacodynamics; Subcutaneous

Indexed keywords

CHORIONIC GONADOTROPIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; EVALUATION; FEMALE; FERTILIZATION IN VITRO; HUMAN; INJECTION; OVARY FOLLICLE FLUID; PRIORITY JOURNAL; PROSPECTIVE STUDY; PURIFICATION;

EID: 0037381343     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(02)04918-X     Document Type: Article

References (11)

1. Nagata Y., Honjou K., Sonada M., Sumii Y., Inoue Y., Kawarabayashi T. Pharmacokinetics of exogenous gonadotropin and ovarian response in in vitro fertilization. Fertil Steril. 72:1999;235-239.
2. Burris A.S., Rodbard H.W., Winters S.J., Sherins R.J. Gonadotropin therapy in men with hypogonadotropic hypogonadism the response to human chorionic gonadotropin is predicted by initial testicular size. J Clin Endocrinol Metab. 66:1988;1144-1151.
3. Finkel D.M., Phillips J.L., Snyder P.J. Stimulation of spermatogenesis by gonadotropins in men with hypogonadotropic hypogonadism. N Engl J Med. 313:1985;651-655.
4. Frankfurter D, Oskowitz SP, Alper MM, Berger MJ, Penzias AS, Thompson IE, et al. Subcutaneous vs intramuscular administration of hCG during an IVF cycle: effect on outcome. Fertil Steril 1998;S399:676.
5. Elkind-Hirsch K.E., Bello S., Esparcia L., Phillips K., Sheiko A., McNichol M. Serum human chorionic gonadotropin levels are correlated with body mass index rather than route of administration in women undergoing in vitro fertilization - embryo transfer using human menopausal gonadotropin and intracytoplasmic sperm injection. Fertil Steril. 75:2001;700-704.
6. Jones K.P., Hatasaka H.H., Peterson C.M., Aoki V., Campbell B., Carrell D.T. Body mass index (BMI) is inversely related to intrafollicular hCG levels and pregnancy rates of IVF patients. Fertil Steril. 74:2000;S176.
7. Saal W., Glowania H.J., Hengst W., Happ J. Pharmacodynamics and pharmacokinetics after subcutaneous and intramuscular injection of human chorionic gonadotropin. Fertil Steril. 56:1991;225-229.
8. Franchimont M.D., Hazee-Hagelstein M.T., Hazout A., Frydman R., Schatz B., Demerle F. Correlation between follicular fluid content and the results of in vitro fertilization and embryo transfer. I. Sex steroids. Fertil Steril. 52:1989;1006-1011.
9. Zegers-Hochschild F., Fernandez E., Mackenna A., Fabres C., Altieri E., Lopez T. The empty follicle syndrome a pharmaceutical industry syndrome. Hum Reprod. 10:1995;2262-2265.
10. Induction of ovulation in World Health Organization group II anovulatory women undergoing follicle-simulating hormone a comparison of recombinant gonadotropin (rhCG) and urinary hCG. Fertil Steril. 75:2001;1111-1118.
11. Nader S., Berkowitz A.S. Study of the pharmacokinetics of human chorionic gonadotropin and its relation to ovulation. J in Vitro Fert Embr Transf. 7:1990;114-118.