A comparison of the rate of recovery of 13CO2 in exhaled breath with 2H in body water following ingestion of [2H/13C]octanoic acid in a dog

Research in Veterinary Science

Volumn 74, Issue 2, 2003, Pages 123-127

  Wyse, C A ^a,b   Yam, P S ^a   Slater, C ^b   Cooper, J M ^b   Preston, T ^c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c SCOTTISH UNIVERSITIES ENVIRONMENTAL RESEARCH CENTRE   (United Kingdom)

Author keywords

Breath test; Gastric emptying; Saliva collection

Indexed keywords

CARBON 13; CARBON DIOXIDE; DEUTERIUM; ISOTOPE; OCTANOIC ACID; WATER;

ANIMAL EXPERIMENT; ARTICLE; BODY WATER; BREATH ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DOG; EXCRETION; EXPIRED AIR; FATTY ACID METABOLISM; FEMALE; INGESTION; NONHUMAN; SALIVA ANALYSIS; TEST MEAL;

ANIMALS; BICARBONATES; BODY FLUIDS; BREATH TESTS; CARBON DIOXIDE; CARBON ISOTOPES; DEUTERIUM; DOGS; FEMALE; KINETICS; OCTANOIC ACIDS; SALIVA; TIME FACTORS; WATER;

CANIS FAMILIARIS; EQUUS CABALLUS;

EID: 0037381225     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5288(02)00178-9     Document Type: Article

References (22)

1. Altman, P.L., Dittmer, D.S., 1964. In: Biology Data Book, first edition, Federation of American Societies for Experimental Biology, Washington, p. 121.
2. Beerda, B., Schilder, M.B.H., Janssen, N.S.C.R.M., et al., 1996. The use of saliva cortisol, urinary cortisol, and catecholamine measurements for a non-invasive assessment of stress responses in dogs. Horm. Behav. 30, 272-279.
3. 2H octanoic acid. Gut 43, S30.
4. Bluck, L.J.C., Harding, M., French, S., et al., 2002. Measurement of gastric emptying in man using deuterated octanoic acid. Rapid Commun. Mass Spectrom. 16, 127-133.
5. 2O-labeled beverages. J. Appl. Physiol. 63, 2060-2066.
6. C]octanoic acid breath test for gastric emptying of solids. Gastroenterology 114, A745.
7. Ghoos, Y.F., Maes, B.D., Geypens, B.J., et al., 1993. Measurement of gastric emptying rate of solids by means of a carbon-labelled octanoic, acid breath test. Gastroenterology 104, 1640-1647.
8. 13C-Obt with deuterated octanoic acid. Stable Isotope Mass Spectrometry Users Group (Simsug) Annual Meeting, Glasgow, 2001.
9. Maes, B.D., 1994. Measurement of gastric emptying using dynamic breath analysis. PhD Thesis, University of Leuven.
10. Mauderly, J.L., 1974. Evaluation of the grade pony as a pulmonary function model. Am. J. Vet. Res. 35, 1025-1029.
11. Pagani, F., Sagrada, A., Brambilla, A., et al., 1988. A model for studying saliva secretion in the conscious dog. Arch. Int. Pharmacodyn. Ther. 291, 253-262.
12. Peachey, S.E., Dawson, J.M., Harper, E.J., 2000. Gastrointestinal transit times in young and old cats. Comp. Biochem. Physiol. A 126, 85-90.
13. 2O by continuous-flow isotope ratio mass spectrometry. Anal. Chem. 67, 1992-1997.
14. Schwabe, A.D., Bennett, L.R., Bowman, L.P., 1964. Octanoic acid absorption and oxidation in humans. J. Appl. Physiol. 19, 335-337.
15. Scrimgeour, C.M., Rollo, M.M., Mudambo, S.M.K.T., et al., 1993. A simplified method for deuterium hydrogen isotope ratio measurements on water samples of biological origin. Biol. Mass. Spectrom. 22, 383-387.
16. Siegel, J.A., Urbain, J.-L., Adler, L.P., et al., 1988. Biphasic nature of gastric emptying. Gut 29, 85-89.
17. Slater, C., Preston, T., Weaver, L.T., 2001. Stable isotopes and the international system of units. Rapid. Commun. Mass Spectrom. 15, 1270-1273.
18. Speakman, J.R., Perez-Camargo, G., Mccappin, T., et al., 2001. Validation of the doubly-labelled water technique in the domestic dog (Canis familiaris). Br. J. Nutr. 85, 75-87.
19. 13C]octanoic acid breath test for measurement of gastric emptying rate of solids using radioscintigraphy. Equine Vet. J., in press.
20. 13C]octanoic acid breath test. Clin. Exp. Pharmacol. Physiol. 9, 671-675.
21. Vincent, I.C., Michell, A.R., 1992. Comparison of cortisol concentrations in saliva and plasma of dogs. Res. Vet. Sci. 53, 342-345.
22. 13C]octanoic acid breath test for assessment of solid phase gastric emptying in dogs. Am. J. Vet. Res. 62, 1939-1944.