-
1
-
-
0032077682
-
Positive and negative regulatory mechanisms that mediate long-term memory storage
-
Abel T. and Kandel E. R. (1998) Positive and negative regulatory mechanisms that mediate long-term memory storage. Brain Res. Brain Res. Rev. 2-3, 360-378.
-
(1998)
Brain Res. Brain Res. Rev.
, vol.2-3
, pp. 360-378
-
-
Abel, T.1
Kandel, E.R.2
-
2
-
-
0028280455
-
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
-
Alberini C. M., Ghirardi M., Metz R. and Kandel E. R. (1994) C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia. Cell 76, 1099-1114.
-
(1994)
Cell
, vol.76
, pp. 1099-1114
-
-
Alberini, C.M.1
Ghirardi, M.2
Metz, R.3
Kandel, E.R.4
-
3
-
-
0036580677
-
Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length
-
de Almeida L. P., Ross C. A., Zala D., Aebischer P. and Deglon N. (2002) Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length. J. Neurosci. 22, 3473-3483.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3473-3483
-
-
De Almeida, L.P.1
Ross, C.A.2
Zala, D.3
Aebischer, P.4
Deglon, N.5
-
4
-
-
0031918640
-
Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: Correlation between the density of inclusions and IT15 IT15 CAG triplet repeat length
-
Becher M. W., Kotzuk J. A., Sharp A. H., Davies S. W., Bates G. P., Price D. L. and Ross C. A. (1998) Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 IT15 CAG triplet repeat length. Neurobiol. Dis. 4, 387-397.
-
(1998)
Neurobiol. Dis.
, vol.4
, pp. 387-397
-
-
Becher, M.W.1
Kotzuk, J.A.2
Sharp, A.H.3
Davies, S.W.4
Bates, G.P.5
Price, D.L.6
Ross, C.A.7
-
5
-
-
0032815680
-
Replicating Huntington's disease phenotype in experimental animals
-
Brouillet E., Conde F., Beal M. F. and Hantraye P. (1999) Replicating Huntington's disease phenotype in experimental animals. Prog. Neurobiol. 59, 427-468.
-
(1999)
Prog. Neurobiol.
, vol.59
, pp. 427-468
-
-
Brouillet, E.1
Conde, F.2
Beal, M.F.3
Hantraye, P.4
-
6
-
-
0037047123
-
Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis
-
Chai Y., Shao J., Miller V. M., Williams A. and Paulson H. L. (2002) Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis. Proc. Natl Acad. Sci. USA 99, 9310-9315.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9310-9315
-
-
Chai, Y.1
Shao, J.2
Miller, V.M.3
Williams, A.4
Paulson, H.L.5
-
7
-
-
0032911634
-
Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia
-
Chain D. G., Casadio A., Schacher S., Hegde A. N., Valbrun M., Yamamoto N., Goldberg A. L., Bartsch D., Kandel E. R. and Schwartz J. H. (1999) Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia. Neuron 22, 147-156.
-
(1999)
Neuron
, vol.22
, pp. 147-156
-
-
Chain, D.G.1
Casadio, A.2
Schacher, S.3
Hegde, A.N.4
Valbrun, M.5
Yamamoto, N.6
Goldberg, A.L.7
Bartsch, D.8
Kandel, E.R.9
Schwartz, J.H.10
-
8
-
-
7144253143
-
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture
-
Cooper J. K., Schilling G., Peters M. F., Herring W. J., Sharp A. H., Kaminsky Z., Masone J., Khan F. A., Delanoy M., Borchelt D. R., Dawson V. L., Dawson T. M. and Ross C. A. (1998) Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. Hum. Mol. Genet. 7, 783-790.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 783-790
-
-
Cooper, J.K.1
Schilling, G.2
Peters, M.F.3
Herring, W.J.4
Sharp, A.H.5
Kaminsky, Z.6
Masone, J.7
Khan, F.A.8
Delanoy, M.9
Borchelt, D.R.10
Dawson, V.L.11
Dawson, T.M.12
Ross, C.A.13
-
9
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies S. W., Turmaine M., Cozens B. A., DiFiglia M., Sharp A. H., Ross C. A., Scherzinger E., Wanker E. E., Mangiarini L. and Bates G. P. (1997) Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell 90, 537-548.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
DiFiglia, M.4
Sharp, A.H.5
Ross, C.A.6
Scherzinger, E.7
Wanker, E.E.8
Mangiarini, L.9
Bates, G.P.10
-
10
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M., Sapp E., Chase K. O., Davies S. W., Bates G. P., Vonsattel J. P. and Aronin N. (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277, 1990-1993.
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
12
-
-
0037111980
-
Integration of long-term-memory-related synaptic plasticity involves bi-directional regulation of gene expression and chromatin structure
-
Guan Z., Giustetto M., Lomvardas S., Kim J., Miniaci M. C., Schwarz J. H., Thomas D. and Kandel E. R. (2002) Integration of long-term-memory-related synaptic plasticity involves bi-directional regulation of gene expression and chromatin structure. Cell 111, 483-493.
-
(2002)
Cell
, vol.111
, pp. 483-493
-
-
Guan, Z.1
Giustetto, M.2
Lomvardas, S.3
Kim, J.4
Miniaci, M.C.5
Schwarz, J.H.6
Thomas, D.7
Kandel, E.R.8
-
13
-
-
0033119123
-
Nuclear and neuropil aggregates in Huntington's disease: Relationship to neuropathology
-
Gutekunst C. A., Li S. H., Yi H., Mulroy J. S., Kuemmerle S., Jones R., Rye D., Ferrante R. J., Hersch S. M. and Li X. J. (1999) Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. J. Neurosci. 19, 2522-2534.
-
(1999)
J. Neurosci.
, vol.19
, pp. 2522-2534
-
-
Gutekunst, C.A.1
Li, S.H.2
Yi, H.3
Mulroy, J.S.4
Kuemmerle, S.5
Jones, R.6
Rye, D.7
Ferrante, R.J.8
Hersch, S.M.9
Li, X.J.10
-
14
-
-
0004293145
-
-
WB Saunders, London
-
Harper P. S., ed. (1991) Huntington's Disease, Vol. 22, pp. 141-178. WB Saunders, London.
-
(1991)
Huntington's Disease
, vol.22
, pp. 141-178
-
-
Harper, P.S.1
-
15
-
-
0033574216
-
Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract
-
Hazeki N., Nakamura K., Goto J. and Kanazawa I. (1999) Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract. Biochem. Biophys. Res. Commun. 256, 361-366.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.256
, pp. 361-366
-
-
Hazeki, N.1
Nakamura, K.2
Goto, J.3
Kanazawa, I.4
-
16
-
-
0030887633
-
Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia
-
Hegde A. N., Inokuchi K., Pei W., Casadio A., Ghirardi M., Chain D. G., Martin K. C., Kandel E. R. and Schwartz J. H. (1997) Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia. Cell 89, 115-126.
-
(1997)
Cell
, vol.89
, pp. 115-126
-
-
Hegde, A.N.1
Inokuchi, K.2
Pei, W.3
Casadio, A.4
Ghirardi, M.5
Chain, D.G.6
Martin, K.C.7
Kandel, E.R.8
Schwartz, J.H.9
-
17
-
-
0035997016
-
Protein aggregation in Huntington's disease
-
Hoffner G. and Djian P. (2002) Protein aggregation in Huntington's disease. Biochimie 84, 273-278.
-
(2002)
Biochimie
, vol.84
, pp. 273-278
-
-
Hoffner, G.1
Djian, P.2
-
18
-
-
17344362229
-
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch
-
Igarashi S., Koide R., Shimohata T., Yamada M., Hayashi Y., Takano H., Date H., Oyake M., Sato T., Sato A., Egawa S., Ikeuchi T., Tanaka H., Nakano R., Tanaka K., Hozumi I., Inuzuka T., Takahashi H. and Tsuji S. (1998) Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch. Nat. Genet. 18, 111-117.
-
(1998)
Nat. Genet.
, vol.18
, pp. 111-117
-
-
Igarashi, S.1
Koide, R.2
Shimohata, T.3
Yamada, M.4
Hayashi, Y.5
Takano, H.6
Date, H.7
Oyake, M.8
Sato, T.9
Sato, A.10
Egawa, S.11
Ikeuchi, T.12
Tanaka, H.13
Nakano, R.14
Tanaka, K.15
Hozumi, I.16
Inuzuka, T.17
Takahashi, H.18
Tsuji, S.19
-
19
-
-
0035336658
-
Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release
-
Jana N. R., Zemskov E. A., Wang G. H. and Nukina N. (2001) Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release. Hum. Mol. Genet. 10, 1049-1059.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1049-1059
-
-
Jana, N.R.1
Zemskov, E.A.2
Wang, G.H.3
Nukina, N.4
-
20
-
-
0030604221
-
Parameters influencing ectopic gene expression in Aplysia neurons
-
Kaang B. K. (1996) Parameters influencing ectopic gene expression in Aplysia neurons. Neurosci. Lett. 221, 29-32.
-
(1996)
Neurosci. Lett.
, vol.221
, pp. 29-32
-
-
Kaang, B.K.1
-
22
-
-
0027416894
-
Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons
-
Kaang B. K., Kandel E. R. and Grant S. G. (1993) Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons. Neuron 10, 427-435.
-
(1993)
Neuron
, vol.10
, pp. 427-435
-
-
Kaang, B.K.1
Kandel, E.R.2
Grant, S.G.3
-
23
-
-
0034307476
-
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy
-
Kegel K. B., Kim M., Sapp E., McIntyre C., Castano J. G., Aronin N. and DiFiglia M. (2000) Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy. J. Neurosci. 20, 7268-7278.
-
(2000)
J. Neurosci.
, vol.20
, pp. 7268-7278
-
-
Kegel, K.B.1
Kim, M.2
Sapp, E.3
McIntyre, C.4
Castano, J.G.5
Aronin, N.6
DiFiglia, M.7
-
24
-
-
0034845861
-
Overexpression of and RNA interference with the CCAAT enhancer-binding protein on long-term facilitation of Aplysia sensory to motor synapses
-
Lee J. A., Kim H. K., Kim K. H., Han J. H., Lee Y. S., Lim C. S., Chang D. J., Kubo T. and Kaang B. K. (2001) Overexpression of and RNA interference with the CCAAT enhancer-binding protein on long-term facilitation of Aplysia sensory to motor synapses. Learning Mem. 8, 220-226.
-
(2001)
Learning Mem.
, vol.8
, pp. 220-226
-
-
Lee, J.A.1
Kim, H.K.2
Kim, K.H.3
Han, J.H.4
Lee, Y.S.5
Lim, C.S.6
Chang, D.J.7
Kubo, T.8
Kaang, B.K.9
-
25
-
-
0031945025
-
Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats
-
Li S. H. and Li X. J. (1998) Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats. Hum. Mol. Genet. 7, 777-782.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 777-782
-
-
Li, S.H.1
Li, X.J.2
-
26
-
-
0033168302
-
Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin
-
Li S. H., Cheng A. L., Li H. and Li X. J. (1999) Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin. J. Neurosci. 19, 5159-5172.
-
(1999)
J. Neurosci.
, vol.19
, pp. 5159-5172
-
-
Li, S.H.1
Cheng, A.L.2
Li, H.3
Li, X.J.4
-
27
-
-
0034426013
-
Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity
-
Li H., Li S. H., Johnston H., Shelbourne, P. F. and Li X. J. (2000a) Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity. Nat. Genet. 25, 365-369.
-
(2000)
Nat. Genet.
, vol.25
, pp. 365-369
-
-
Li, H.1
Li, S.H.2
Johnston, H.3
Shelbourne, P.F.4
Li, X.J.5
-
28
-
-
0033848272
-
Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth
-
Li S. H., Li H., Torre E. R. and Li X. J. (2000b) Expression of huntingtin-associated protein-1 in neuronal cells implicates a role in neuritic growth. Mol. Cell. Neurosci. 16, 168-183.
-
(2000)
Mol. Cell. Neurosci.
, vol.16
, pp. 168-183
-
-
Li, S.H.1
Li, H.2
Torre, E.R.3
Li, X.J.4
-
29
-
-
0037150781
-
Hydrogen peroxide-induced cell death in cultured Aplysia sensory neurons
-
Lim C. S., Lee J. C., Kim S. D., Chang D. J. and Kaang B. K. (2002) Hydrogen peroxide-induced cell death in cultured Aplysia sensory neurons. Brain Res. 941, 137-145.
-
(2002)
Brain Res.
, vol.941
, pp. 137-145
-
-
Lim, C.S.1
Lee, J.C.2
Kim, S.D.3
Chang, D.J.4
Kaang, B.K.5
-
30
-
-
0031680014
-
A cellular model that recapitulates major pathogenic steps of Huntington's disease
-
Lunkes A. and Mandel J. L. (1998) A cellular model that recapitulates major pathogenic steps of Huntington's disease. Hum. Mol. Genet. 7, 1355-1361.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 1355-1361
-
-
Lunkes, A.1
Mandel, J.L.2
-
31
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
Luthi-Carter R., Strand A., Peters N. L., Solano S. M., Hollingsworth Z. R., Menon A. S., Frey A. S., Spektor B. S., Penney E. B., Schilling G., Ross C. A., Borchelt D. R., Tapscott S. J., Young A. B., Cha J. H. and Olson J. M. (2000) Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum. Mol. Genet. 9, 1259-1271.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
Ross, C.A.11
Borchelt, D.R.12
Tapscott, S.J.13
Young, A.B.14
Cha, J.H.15
Olson, J.M.16
-
32
-
-
0031444409
-
Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: A function for local protein synthesis in memory storage
-
Martin K. C., Casadio A., Zhu H. E. Y., Rose J. C., Chen M., Bailey C. H. and Kandel E. R. (1997) Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage. Cell 91, 927-938.
-
(1997)
Cell
, vol.91
, pp. 927-938
-
-
Martin, K.C.1
Casadio, A.2
Zhu, H.E.Y.3
Rose, J.C.4
Chen, M.5
Bailey, C.H.6
Kandel, E.R.7
-
33
-
-
0032032006
-
Cognitive neuroscience and the study of memory. Cognitive neuroscience and the study of memory
-
Milner B., Squire L. R. and Kandel E. R. (1998) Cognitive neuroscience and the study of memory. Cognitive neuroscience and the study of memory. Neuron 20, 445-468.
-
(1998)
Neuron
, vol.20
, pp. 445-468
-
-
Milner, B.1
Squire, L.R.2
Kandel, E.R.3
-
34
-
-
0022835911
-
A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia
-
Montarolo P. G., Goelet P., Castellucci V. F., Morgan J., Kandel E. R. and Schacher S. (1986) A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia. Science 234, 1249-1254.
-
(1986)
Science
, vol.234
, pp. 1249-1254
-
-
Montarolo, P.G.1
Goelet, P.2
Castellucci, V.F.3
Morgan, J.4
Kandel, E.R.5
Schacher, S.6
-
35
-
-
0034234519
-
Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation
-
Murphy K. P., Carter R. J., Lione L. A., Mangiarini L., Mahal A., Bates G. P., Dunnett S. B. and Morton A. J. (2000) Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation. J. Neurosci. 20, 5115-5123.
-
(2000)
J. Neurosci.
, vol.20
, pp. 5115-5123
-
-
Murphy, K.P.1
Carter, R.J.2
Lione, L.A.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
Dunnett, S.B.7
Morton, A.J.8
-
36
-
-
0035937523
-
Interference by huntingtin and atrophin-with CBP-mediated transcription leading to cellular toxicity
-
Nucifora F. C. Jr, Sasaki M., Peters M. F., Huang H., Cooper J. K., Yamada M., Takahashi H., Tsuji S., Troncoso J., Dawson V. L., Dawson T. M. and Ross C. A. (2001) Interference by huntingtin and atrophin-with CBP-mediated transcription leading to cellular toxicity. Science 291, 2423-2428.
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora F.C., Jr.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
Yamada, M.6
Takahashi, H.7
Tsuji, S.8
Troncoso, J.9
Dawson, V.L.10
Dawson, T.M.11
Ross, C.A.12
-
37
-
-
0035818590
-
Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death
-
Parker J. A., Connolly J. B., Wellington C., Hayden M., Dausset J. and Neri C. (2001) Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death. Proc. Natl Acad. Sci. USA 98, 13318-13323.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13318-13323
-
-
Parker, J.A.1
Connolly, J.B.2
Wellington, C.3
Hayden, M.4
Dausset, J.5
Neri, C.6
-
38
-
-
0034028473
-
Toward an understanding of polyglutamine neurodegeneration
-
Paulson H. L. (2000) Toward an understanding of polyglutamine neurodegeneration. Brain Pathol. 10, 293-299.
-
(2000)
Brain Pathol.
, vol.10
, pp. 293-299
-
-
Paulson, H.L.1
-
39
-
-
0030850412
-
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3
-
Paulson H. L., Perez M. K., Trottier Y., Trojanowski J. Q., Subramony S. H., Das S. S., Vig P., Mandel J. L., Fischbeck K. H. and Pittman R. N. (1997) Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3. Neuron 19, 333-344.
-
(1997)
Neuron
, vol.19
, pp. 333-344
-
-
Paulson, H.L.1
Perez, M.K.2
Trottier, Y.3
Trojanowski, J.Q.4
Subramony, S.H.5
Das, S.S.6
Vig, P.7
Mandel, J.L.8
Fischbeck, K.H.9
Pittman, R.N.10
-
40
-
-
0028283985
-
Glutamine repeats as polar zippers: Their possible role in inherited neurodegenerative diseases
-
Perutz M. F., Johnson T., Suzuki M. and Finch J. T. (1994) Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases. Proc. Natl Acad. Sci., USA 91, 5355-5358.
-
(1994)
Proc. Natl. Acad. Sci., USA
, vol.91
, pp. 5355-5358
-
-
Perutz, M.F.1
Johnson, T.2
Suzuki, M.3
Finch, J.T.4
-
41
-
-
0036566266
-
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
-
Ravikumar B., Duden R. and Rubinsztein D. C. (2002) Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum. Mol. Genet. 11, 1107-1117.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1107-1117
-
-
Ravikumar, B.1
Duden, R.2
Rubinsztein, D.C.3
-
42
-
-
0037059042
-
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity
-
August 20 [Epub ahead of print]
-
Sakahira H., Breuer P., Hayer-Hartl M. K. and Hartl F. U. (2002) Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity. Proc. Natl Acad. Sci. USA August 20 [Epub ahead of print].
-
(2002)
Proc. Natl. Acad. Sci. USA
-
-
Sakahira, H.1
Breuer, P.2
Hayer-Hartl, M.K.3
Hartl, F.U.4
-
43
-
-
0032987513
-
Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington's disease
-
Sapp E., Penney J., Young A., Aronin N., Vonsattel J. P. and DiFiglia M. (1999) Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington's disease. J. Neuropathol. Exp. Neurol. 58, 165-173.
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 165-173
-
-
Sapp, E.1
Penney, J.2
Young, A.3
Aronin, N.4
Vonsattel, J.P.5
DiFiglia, M.6
-
44
-
-
0033046477
-
Adenovirus-mediated expression of mutant DRPLA proteins with expanded polyglutamine stretches in neuronally differentiated PC12 cells. Preferential intranuclear aggregate formation and apoptosis
-
Sato A., Shimohata T., Koide R., Takano H., Sato T., Oyake M., Igarashi S., Tanaka K., Inuzuka T., Nawa H. and Tsuji S. (1999) Adenovirus-mediated expression of mutant DRPLA proteins with expanded polyglutamine stretches in neuronally differentiated PC12 cells. Preferential intranuclear aggregate formation and apoptosis. Hum. Mol. Genet. 8, 997-1006.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 997-1006
-
-
Sato, A.1
Shimohata, T.2
Koide, R.3
Takano, H.4
Sato, T.5
Oyake, M.6
Igarashi, S.7
Tanaka, K.8
Inuzuka, T.9
Nawa, H.10
Tsuji, S.11
-
45
-
-
0021043993
-
Neurite regeneration by Aplysia neurons in dissociated cell culture: Modulation by Aplysia hemolymph and the presence of the initial axonal segment
-
Schacher S. and Proshansky E. (1986) Neurite regeneration by Aplysia neurons in dissociated cell culture: modulation by Aplysia hemolymph and the presence of the initial axonal segment. J Neurosci. 3, 2403-2413.
-
(1986)
J. Neurosci.
, vol.3
, pp. 2403-2413
-
-
Schacher, S.1
Proshansky, E.2
-
46
-
-
18544400323
-
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
-
Scherzinger E., Lurz R., Turmaine M., Mangiarini L., Hollenbach B., Hasenbank R., Bates G. P., Davies S. W., Lehrach H. and Wanker E. E. (1997) Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo. Cell 90, 549-558.
-
(1997)
Cell
, vol.90
, pp. 549-558
-
-
Scherzinger, E.1
Lurz, R.2
Turmaine, M.3
Mangiarini, L.4
Hollenbach, B.5
Hasenbank, R.6
Bates, G.P.7
Davies, S.W.8
Lehrach, H.9
Wanker, E.E.10
-
47
-
-
0035139109
-
Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases
-
Sherman M. Y. and Goldberg A. L. (2001) Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases. Neuron 29, 15-32.
-
(2001)
Neuron
, vol.29
, pp. 15-32
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
48
-
-
0037101839
-
Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses
-
Sipione S., Rigamonti D., Valenza M., Zuccato C., Conti L., Pritchard J., Kooperberg C., Olson J. M. and Cattaneo E. (2002) Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Hum. Mol. Genet. 11, 1953-1965.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1953-1965
-
-
Sipione, S.1
Rigamonti, D.2
Valenza, M.3
Zuccato, C.4
Conti, L.5
Pritchard, J.6
Kooperberg, C.7
Olson, J.M.8
Cattaneo, E.9
-
49
-
-
12944263711
-
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
-
Steffan J. S., Kazantsev A., Spasic-Boskovic O., Greenwald M., Zhu Y. Z., Gohler H., Wanker E. E., Bates G. P., Housman D. E. and Thompson L. M. (2000) The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription. Proc. Natl Acad. Sci. USA 97, 6763-6768.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6763-6768
-
-
Steffan, J.S.1
Kazantsev, A.2
Spasic-Boskovic, O.3
Greenwald, M.4
Zhu, Y.Z.5
Gohler, H.6
Wanker, E.E.7
Bates, G.P.8
Housman, D.E.9
Thompson, L.M.10
-
50
-
-
0032897760
-
Impaired synaptic plasticity in mice carrying the Huntington's disease mutation
-
Usdin M. T., Shelboume P. F., Myers R. M. and Madison D. V. (1999) Impaired synaptic plasticity in mice carrying the Huntington's disease mutation. Hum. Mol. Genet. 8, 839-846.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 839-846
-
-
Usdin, M.T.1
Shelboume, P.F.2
Myers, R.M.3
Madison, D.V.4
-
51
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel J. P., Myers R. H., Stevens T. J., Ferrante R. J., Bird E. D. and Richardson E. P. Jr (1985) Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 44, 559-577.
-
(1985)
J. Neuropathol. Exp. Neurol.
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
Myers, R.H.2
Stevens, T.J.3
Ferrante, R.J.4
Bird, E.D.5
Richardson E.P., Jr.6
-
52
-
-
0034754875
-
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation
-
Waelter S., Boeddrich A., Lurz R., Scherzinger E., Lueder G., Lehrach H. and Wanker E. E. (2001) Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. Mol. Biol. Cell. 12, 1393-1407.
-
(2001)
Mol. Biol. Cell.
, vol.12
, pp. 1393-1407
-
-
Waelter, S.1
Boeddrich, A.2
Lurz, R.3
Scherzinger, E.4
Lueder, G.5
Lehrach, H.6
Wanker, E.E.7
-
53
-
-
0033588476
-
Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells
-
Wang G. H., Mitsui K., Kotliarova S., Yamashita A., Nagao Y., Tokuhiro S., Iwatsubo T., Kanazawa I. and Nukina N. (1999) Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells. Neuroreport 10, 2435-2438.
-
(1999)
Neuroreport
, vol.10
, pp. 2435-2438
-
-
Wang, G.H.1
Mitsui, K.2
Kotliarova, S.3
Yamashita, A.4
Nagao, Y.5
Tokuhiro, S.6
Iwatsubo, T.7
Kanazawa, I.8
Nukina, N.9
-
54
-
-
0031056478
-
HIP-1: A huntingtin interacting protein isolated by the yeast two-hybrid system
-
Wanker E. E., Rovira C., Scherzinger E., Hasenbank R., Walter S., Tait D., Colicelli J. and Lehrach H. (1997) HIP-1: a huntingtin interacting protein isolated by the yeast two-hybrid system. Hum. Mol. Genet. 6, 487-495.
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 487-495
-
-
Wanker, E.E.1
Rovira, C.2
Scherzinger, E.3
Hasenbank, R.4
Walter, S.5
Tait, D.6
Colicelli, J.7
Lehrach, H.8
-
55
-
-
0035880474
-
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease
-
Wyttenbach A., Swartz J., Kita H., Thykjaer T., Carmichael J., Bradley J., Brown R., Maxwell M., Schapira A., Omtoft T. F., Kato K. and Rubinsztein D. C. (2001) Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum. Mol. Genet. 10, 1829-1845.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1829-1845
-
-
Wyttenbach, A.1
Swartz, J.2
Kita, H.3
Thykjaer, T.4
Carmichael, J.5
Bradley, J.6
Brown, R.7
Maxwell, M.8
Schapira, A.9
Omtoft, T.F.10
Kato, K.11
Rubinsztein, D.C.12
|