Atropine availability as an antidote for nerve agent casualties: Validated rapid reformulation of high-concentration atropine from bulk powder

Annals of Emergency Medicine

Volumn 41, Issue 4, 2003, Pages 453-456

  Geller, Robert J ^a,b   Lopez, Gaylord P ^b   Cutler, Stephen ^d   Lin, Diana ^c   Bachman, George F ^c   Gorman, Susan E ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Georgia Poison Center   (United States)

^c GRADY HEALTH SYSTEM   (United States)

^d MERCER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; NERVE GAS; ORGANOPHOSPHATE INSECTICIDE; PYROGEN;

ACCURACY; ARTICLE; CHOLINERGIC SYNDROME; CHOLINERGIC SYSTEM; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG POTENCY; DRUG STABILITY; DRUG STORAGE; DRUG SYNTHESIS; FREEZING; LOW TEMPERATURE; NEUROTOXICITY; POWDER; PRACTICE GUIDELINE; PRIORITY JOURNAL;

EID: 0037380874     PISSN: 01960644     EISSN: None     Source Type: Journal    
DOI: 10.1067/mem.2003.103     Document Type: Article

References (7)

1. Dart RC, Goldfrank LR, Chyka PA, et al. Combined evidence-based literature analysis and consensus guidelines for stocking of emergency antidotes in the United States. Ann Emerg Med. 2000;36:126-132.
2. Dart RC, Stark Y, Fulton B, et al. Insufficient stocking of poisoning antidotes in hospital pharmacies. JAMA. 1996;276:1508-1510.
3. Woolf AD, Chrisanthus K. On-site availability of selected antidotes: results of a survey of Massachusetts hospitals. Am J Emerg Med. 1997;15:62-66.
4. Teresi WM, King WD. Survey of the stocking of poison antidotes in Alabama hospitals. South Med J. 1999;92:1151-1156.
5. Juurlink DN, McGuigan MA, Paton TW, et al. Availability of antidotes at acute care hospitals in Ontario. CMAJ. 2001;165:27-30.
6. US Food and Drug Administration Modernization Act of 1997, 21 USC 353a §503a.
7. American Society of Healthcare Pharmacists. ASHP guidelines on quality assurance for pharmacy-prepared sterile products. Available at: http://www.ashp.org/bestpractices/drugdistribution/Drug%20 Distribution%20and%20Control%20Preparation%20Handling%20 Guideline%20Assu.%20for%20Phar.%20Prep.%20Ster.%20Prod.pdf. Accessed December 19, 2001.