Lack of association between angiotensin converting enzyme (ACE) genotype, serum ACE activity, and haemodynamics in patients with primary pulmonary hypertension

Heart

Volumn 89, Issue 4, 2003, Pages 445-446

  Hoeper, Marius M ^a   Tacacs, A ^a   Stellmacher, U ^a   Lichtinghagen, R ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; ENZYME ACTIVITY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEART FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEMODYNAMICS; HUMAN; LUNG BLOOD VESSEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PULMONARY HYPERTENSION;

EID: 0037379853     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/heart.89.4.445     Document Type: Article

References (5)

1. D'Alonzo GE, Barst RJ, Ayres SM, et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 1991;115:343-9.
2. Abraham WT, Raynolds MV, Gottschall B, et al. Importance of angiotensin-converting enzyme in pulmonary hypertension. Cardiology 1995;86:9-15.
3. Rigat B, Hubert C, Alhenc-Gelas F, et al. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990;86:1343-6.
4. Schunkert H, Hense HW, Holmer SR, et al. Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. N Engl J Med 1994;330:1634-8.
5. Lindpaintner K, Lee M, Larson MG, et al. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med 1996;334:1023-8.