Novel tetracycline resistance determinant from the oral metagenome

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 4, 2003, Pages 1430-1432

  Diaz Torres, M L ^a   McNab, R ^a,b   Spratt, D A ^a   Villedieu, A ^a   Hunt, N ^a   Wilson, M ^a   Mullany, P ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; DNA ISOLATION; DRUG DETERMINATION; GENE INACTIVATION; GENOME; HUMAN; HUMAN CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SALIVA ANALYSIS; TOOTH PLAQUE;

ADULT; AMINO ACID SEQUENCE; BACTERIA; DENTAL PLAQUE; GENOME, BACTERIAL; HUMANS; MOLECULAR SEQUENCE DATA; SALIVA; TETRACYCLINE RESISTANCE;

EID: 0037379398     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.4.1430-1432.2003     Document Type: Article

References (5)

1. Aminov, R. I., N. Garrigues-Jeanjean, and R. I. Mackie. 2001. Molecular ecology of tetracycline resistance: development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protective proteins. Appl. Environ. Microbiol. 67:22-32.
2. Shoemaker, N. B., H. Vamakis, K. Hayes, and A. A. Salyers. 2001. Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon. Appl. Environ. Microbiol. 67:561-568.
3. Speer, B. S., and A. A. Salyers. 1991. Evidence that a novel tetracycline resistance gene found on two Bacteroides transposons encodes an NADP-requiring oxidoreductase. J. Bacteriol. 173:176-183.
4. Spratt, D. A., A. J. Weightman, and W. G. Wade. 1999. Diversity of oral asaccharolytic Eubacterium species in periodontitis-identification of novel phylotypes representing uncultivated taxa. Oral Microbiol. Immunol. 14:56-59.
5. Wade, W. 2002. Unculturable bacteria - the uncharacterized organisms that cause oral infections. J. R. Soc. Med. 95:81-83.