Expression of the scaffolding subunit A of protein phosphatase 2A during rat testicular development

Biology of Reproduction

Volumn 68, Issue 4, 2003, Pages 1369-1375

  Van den Ham, R ^a   Van Dissel Emiliani, F M F ^a   Van Pelt, A M M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Developmental biology; Phosphatases; Signal transduction; Spermatogenesis; Testis

Indexed keywords

ISOENZYME; PHOSPHOPROTEIN PHOSPHATASE 2A; POLYADENYLATED RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME REGULATION; ENZYME SUBUNIT; FEMALE; FETUS CELL; GONOCYTE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MEIOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SERTOLI CELL; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON MATURATION; TESTIS CELL; TESTIS DEVELOPMENT; UPREGULATION; WESTERN BLOTTING;

AGING; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CELL COUNT; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FETUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; ISOENZYMES; MALE; PHOSPHOPROTEIN PHOSPHATASE; RATS; RATS, WISTAR; SPERMATOZOA; TESTIS;

ANIMALIA;

EID: 0037378646     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.102.004853     Document Type: Article

References (42)

1. De Rooij DG, van Dissel-Emiliani FM. Regulation of proliferation and differentiation of stem cells in the male germ line. In: Potten C (ed.), Stem Cells. San Diego: Academic Press; 1997: 283-313.
2. Van den Ham R, van Dissel-Emiliani FM, van Pelt AM. Identification of candidate genes involved in gonocyte development. J Androl 2002; 23:410-418.
3. Millward TA, Zolnierowicz S, Hemmings BA. Regulation of protein kinase cascades by protein phosphatase 2A. Trends Biochem Sci 1999; 24:186-191.
4. Walton KM, Dixon JE. Protein tyrosine phosphatases. Annu Rev Biochem 1993; 62:101-120.
5. De Paoli-Roach AA, Park IK, Cerovsky V, Csortos C, Durbin SD, Kuntz MJ, Sitikov A, Tang PM, Verin A, Zolnierowicz S. Serine/ threonine protein phosphatases in the control of cell function. Adv Enzyme Regul 1994; 34:199-224.
6. Cohen P. The structure and regulation of protein phosphatases. Annu Rev Biochem 1989; 58:453-508.
7. Kremmer E, Ohst K, Kiefer J, Brewis N, Walter G. Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cells. Mol Cell Biol 1997; 17:1692-1701.
8. Goldberg Y. Protein phosphatase 2A: who shall regulate the regulator? Biochem Pharmacol 1999; 57:321-328.
9. Hendrix P, Turowski P, Mayer-Jaekel RE, Goris J, Hofsteenge J, Merlevede W, Hemmings BA. Analysis of subunit isoforms in protein phosphatase 2A holoenzymes from rabbit and Xenopus. J Biol Chem 1993; 268:7330-7337.
10. Kitagawa Y, Sasaki K, Shima H, Shibuya M, Sugimura T, Nagao M. Protein phosphatases possibly involved in rat spermatogenesis. Biochem Biophys Res Commun 1990; 171:230-235.
11. Sasaki K, Kitagawa Y, Shima H, Irino S, Sugimura T, Nagao M. Production of shorter mRNA for protein phosphatase 2A beta by alternative poly(A) addition. Biochem Biophys Res Commun 1990; 170:169-175.
12. Hatano Y, Shima H, Haneji T, Miura AB, Sugimura T, Nagao M. Expression of PP2A B regulatory subunit beta isotype in rat testis. FEBS Lett 1993; 324:71-75.
13. Zolnierowicz S, Csortos C, Bondor J, Verin A, Mumby MC, De Paoli-Roach AA. Diversity in the regulatory B-subunits of protein phosphatase 2A: identification of a novel isoform highly expressed in brain. Biochemistry 1994; 33:11858-11867.
14. Csortos C, Zolnierowicz S, Bako E, Durbin SD, De Paoli-Roach AA. High complexity in the expression of the B' subunit of protein phosphatase 2A0. Evidence for the existence of at least seven novel isoforms. J Biol Chem 1996; 271:2578-2588.
15. Nagase T, Murakami T, Nozaki H, Inoue R, Nishito Y, Tanabe O, Usui H, Takeda M. Tissue and subcellular distributions, and characterization of rat brain protein phosphatase 2A containing a 72-kDa delta/B' subunit. J Biochem 1997; 122:178-187.
16. van Pelt AM, de Rooij DG. The origin of the synchronization of the seminiferous epithelium in vitamin A-deficient rats after vitamin A replacement. Biol Reprod 1990; 42:677-682.
17. van Pelt AM, van Dissel-Emiliani FM, Gaemers IC, van der Burg MJ, Tanke HJ, de Rooij DG. Characteristics of A spermatogonia and preleptotene spermatocytes in the vitamin A-deficient rat testis. Biol Reprod 1995; 53:570-578.
18. Wilkinson DG, Green J. In situ hybridization and the three-dimensional reconstruction of serial sections. In: Copp AJ, Cockroft DL (eds.), Postimplantation Mammalian Embryos; A Practical Apprcach. Oxford, U.K.: Oxford University Press; 1990: 155-171.
19. Braissant O, Wahli W. A simplified in situ hybridization protocol using non-radioactively labeled probes to detect abundant and rare mRNAs on tissue sections. Biochemica 1998; 1:10-16.
20. Van Pelt AM, de Rooij DG, van der BB, van der Saag PT, Gustafsson JA, Kuiper GG. Ontogeny of estrogen receptor-beta expression in rat testis. Endocrinology 1999; 140:478-483.
21. Van Pelt AM, Morena AR, van Dissel-Emiliani FM, Boitani C, Gaemers IC, de Rooij DG, Stefanini M. Isolation of the synchronized A spermatogonia from adult vitamin A-deficient rat testes. Biol Reprod 1996; 55:439-444.
22. Bosch M, Cayla X, Van HC, Hemmings BA, Ozon R, Merlevede W Goris J. The PR55 and PR65 subunits of protein phosphatase 2A fron Xenopus laevis. Molecular cloning and developmental regulation o expression. Eur J Biochem 1995; 230:1037-1045.
23. Huckins C. The spermatogonial stem cell population in adult rats. V. Their morphology, proliferation and maturation. Anat Rec 1971; 169: 533-557.
24. Oakberg EF. Spermatogonial stem-cell renewal in the mouse. Anat Rec 1971; 169:515-531.
25. Schrans-Stassen BH, van de Kant HJ, de Rooij DG, van Pelt AM Differential expression of c-kit in mouse undifferentiated and differentiating type A spermatogonia. Endocrinology 1999; 140:5894-5900.
26. Van Dissel-Emiliani FM, van Kooten PJ, Boer-Brouwer M, de Rooij DG, van der Donk JA. A monoclonal antibody recognizing a differentiation marker on rat gonocytes. J Reprod Immunol 1993; 23:93-108.
27. Van Haaster LH, de Rooij DG. Spermatogenesis is accelerated in the immature Djungarian and Chinese hamster and rat. Biol Reprod 1993; 49:1229-1235.
28. De Rooij DG. Stem cells in the testis. Int J Exp Pathol 1998; 79:67-80.
29. Orth JM, Jester WFJ, Qiu J. Gonocytes in testes of neonatal rats express the c-kit gene. Mol Reprod Dev 1996; 45:123-131.
30. Orth JM, Qiu J, Jester WF Jr, Pilder S. Expression of the c-kit gene is critical for migration of neonatal rat gonocytes in vitro. Biol Reprod 1997; 57:676-683.
31. Wera S, Hemmings BA. Serine/threonine protein phosphatases. Biochem J 1995; 311:17-29.
32. Hunter T. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 1995; 80:225-236.
33. Mumby MC, Walter G. Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiol Rev 1993; 73: 673-699.
34. Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M. The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the MAP kinase pathway and induces cell proliferation. Cell 1993; 75:887-897.
35. Dolci S, Pellegrini M, Di Agostino S, Geremia R, Rossi P. Signaling through extracellular signal-regulated kinase is required for spermatogonial proliferative response to stem cell factor. J Biol Chem 2001; 276:40225-40233.
36. Alessi DR, Gomez N, Moorhead G, Lewis T, Keyse SM, Cohen P. Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines. Curr Biol 1995; 5:283-295.
37. Millward TA, Zolnierowicz S, Hemmings BA. Regulation of protein kinase cascades by protein phosphatase 2A. Trends Biochem Sci 1999; 24:186-191.
38. Wiltshire T, Park C, Caldwell KA, Handel MA. Induced premature G2/M-phase transition in pachytene spermatocytes includes events unique to meiosis. Dev Biol 1995; 169:557-567.
39. Cobb J, Cargile B, Handel MA. Acquisition of competence to condense metaphase I chromosomes during spermatogenesis. Dev Biol 1999; 205:49-64.
40. Clermont Y, Perey B. Quantitative study of the cell population of the seminiferous tubules of immature rats. Am J Anat 1957; 100:241-268.
41. Cayla X, Van HC, Bosch M, Waelkens E, Vandekerckhove J, Peeters B, Merlevede W, Goris J. Molecular cloning, expression, and characterization of PTPA, a protein that activates the tyrosyl phosphatase activity of protein phosphatase 2A. J Biol Chem 1994; 269:15668-15675.
42. Van Hoof C, Cayla X, Bosch M, Merlevede W, Goris J. The phosphotyrosyl phosphatase activator of protein phosphatase 2A. A novel purification method, immunological and enzymic characterization. Eur J Biochem 1994; 226:899-907.