A single gene on the Staphylococcal multiresistance plasmid pSK1 encodes a novel partitioning system

Journal of Bacteriology

Volumn 185, Issue 7, 2003, Pages 2143-2152

  Simpson, Alice E ^a   Skurray, Ronald A ^a   Firth, Neville ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG RESISTANCE; GENE FUNCTION; GENE LOCUS; GENE ORF245; GENE REPLICATION; MOLECULAR STABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN STABILITY; REPLICON; STAPHYLOCOCCUS; TIME SERIES ANALYSIS; TRANSCRIPTION INITIATION;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; CHROMOSOME SEGREGATION; DNA HELICASES; DNA-BINDING PROTEINS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; MOLECULAR SEQUENCE DATA; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; REPLICON; STAPHYLOCOCCUS AUREUS; TRANS-ACTIVATORS;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0037377854     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.185.7.2143-2152.2003     Document Type: Article

References (60)

1. Apisiridej, S. 1997. Ph.D. thesis. University of Sydney, Sydney, Australia.
2. Austin, S., and K. Nordstrom. 1990. Partition-mediated incompatibility of bacterial plasmids. Cell 60:351-354.
3. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. S. Smith, and K. Struhl. 1990. Current protocols in molecular biology. John Wiley & Sons, Inc., New York, N.Y.
4. Berg, T., N. Firth, S. Apisiridej, A. Hettiaratchi, A. Leelaporn, and R. A. Skurray. 1998. Complete nucleotide sequence of pSK41: evolution of staphylococcal conjugative plasmids, J. Bacteriol. 180:4350-4359.
5. Bouet, J. Y., and B. E. Funnell. 1999. P1 ParA interacts with the P1 partition complex at parS and an ATP-ADP switch controls ParA activities. EMBO J. 18:1415-1424.
6. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
7. Brennan, R. G., and B. W. Matthews. 1989. The helix-turn-helix binding motif. J. Biol. Chem. 264:1903-1906.
8. Bruckner, R. 1992. A series of shuttle vectors for Bacillus subtilis and Escherichia coli. Gene 122:187-192.
9. Burkhard, P., S. V. Strelkov, and J. Stetefeld. 2001. Coiled coils: a highly versatile protein folding motif. Trends Cell Biol. 11:82-88.
10. Cope, L. D., E. R. Lafontaine, C. A. Slaughter, C. A. Hasemann, Jr., C. Aebi, F. W. Henderson, G. H. McCracken, Jr., and E. J. Hansen. 1999. Characterization of the Moraxella catarrhalis uspA1 and uspA2 genes and their encoded products. J. Bacteriol. 181:4026-4034.
11. Dam, M., and K. Gerdes. 1994. Partitioning of plasmid R1. Ten direct repeats flanking the parA promoter constitute a centromere-like partition site parC, that expresses incompatibility. J. Mol. Biol. 236:1289-1298.
12. Davis, M. A., and S. J. Austin. 1988. Recognition of the P1 plasmid centromere analog involves binding of the ParB protein and is modified by a specific host factor. EMBO J. 7:1881-1888.
13. Dodd, I. B., and J. B. Egan. 1990. Improved detection of helix-turn-helix DNA-binding motifs in protein sequences. Nucleic Acids Res. 18:5019-5026.
14. Firth, N., S. Apisiridej, T. Berg, B. A. O'Rourke, S. Curnock, K. G. H. Dyke, and R. A. Skurray. 2000, Replication of staphylococcal multiresistance plasmids. J. Bacteriol. 182:2170-2178.
15. Firth, N., and R. A. Skurray. 2000. The Staphylococcus genetics: accessory elements and genetic exchange, p. 326-338. In V. A. Fischetti, R. P. Novick, J. J. Ferretti, D. A. Portnoy, and J. I. Rood (ed.), Gram-positive pathogens. American Society for Microbiology, Washington, D.C.
16. Fung, E., J. Y. Bouet, and B. E. Funnell. 2001. Probing the ATP-binding site of P1 ParA: partition and repression have different requirements for ATP binding and hydrolysis. EMBO J. 20:4901-4911.
17. Gallie, D. R., and C. I. Kado. 1987. Agrobacterium tumefaciens pTAR parA promoter region involved in autoregulation, incompatibility and plasmid partitioning. J. Mol. Biol. 193:465-478.
18. Gerdes, K., S. Ayora, I. Canosa, R. Ceglowski, R. Diaz-Orejas, T. Franch, A. P. Gultyaev, R. B. Jensen, I. Kobayshi, C. Macpherson, D. Summers, C. M. Thomas, and U. Zielenkiewicz. 2000. Plasmid maintenance systems, p. 49-75. In C. M. Thomas (ed.), The horizontal gene pool. Hardwood Academic Publishers, Amsterdam, The Netherlands.
19. Gerdes, K., J. Moller-Jensen, and R. B. Jensen. 2000. Plasmid and chromosome partitioning: surprises from phylogeny. Mol. Microbiol. 37:455-466.
20. Gering, M., F. Götz, and R. Bruckner. 1996. Sequence and analysis of the replication region of the Staphylococcus xylosus plasmid pSX267. Gene 182: 117-122.
21. Gordon, G. S., and A. Wright. 2000. DNA segregation in bacteria. Annu. Rev. Microbiol. 54:681-708.
22. Greenfield, T. J., T. Franch, K. Gerdes, and K. E. Weaver. 2001. Antisense RNA regulation of the par post-segregational killing system: structural analysis and mechanism of binding of the antisense RNA, RNAII and its target, RNAI. Mol. Microbiol. 42:527-537.
23. Hawley, D. K., and W. R. McClure. 1983. Compilation and analysis of Escherichia coli promoter DNA sequences. Nucleic Acids Res. 11:2237-2255.
24. Hudson, M. C., and G. C. Stewart. 1986. Differential utilization of Staphylococcus aureus promoter sequences by Escherichia coli and Bacillus subtilis. Gene 48:93-100.
25. Jensen, R. B., and K. Gerdes. 1997. Partitioning of plasmid R1. The ParM protein exhibits ATPase activity and interacts with the centromere-like ParR-parC complex. J. Mol. Biol. 269:505-513.
26. Jensen, R. B., and K. Gerdes. 1999. Mechanism of DNA segregation in prokaryotes: ParM partitioning protein of plasmid R1 co-localizes with its replicon during the cell cycle. EMBO J. 18:4076-4084.
27. Jensen, R. B., E. Grohmann, H. Schwab, R. Diaz-Orejas, and K. Gerdes. 1995. Comparison of ccd of F,parDE of RP4, and parD of R1 using a novel conditional replication control system of plasmid R1. Mol. Microbiol. 17: 211-220.
28. Kearney, K., G. F. Fitzgerald, and J. F. Seegers, 2000. Identification and characterization of an active plasmid partition mechanism for the novel Lactococcus lactis plasmid pCI2000. J. Bacteriol, 182:30-37.
29. Khan, S. A., and R. P. Novick. 1983. Complete nucleotide sequence of pT181, a tetracycline-resistance plasmid from Staphylococcus aureus. Plasmid 10:251-259.
30. Leelaporn, A., N. Firth, M. E. Byrne, E. Roper, and R. A. Skurray. 1994. Possible role of insertion sequence IS257 in dissemination and expression of high- and low-level trimethoprim resistance in staphylococci. Antimicrob. Agents Chemother. 38:2238-2244.
31. Lobocka, M., and M. Yarmolinsky. 1996. P1 plasmid partition: a mutational analysis of ParB. J. Mol. Biol. 259:366-382.
32. Lyon, B. R., J. W. May, and R. A. Skurray. 1983. Analysis of plasmids in nosocomial strains of multiple-antibiotic-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 23:817-826.
33. Lyon, B. R., J. W. May, and R. A. Skurray. 1984. Tn4001: a gentamicin and kanamycin resistance transposon in Staphylococcus aureus. Mol. Gen. Genet. 193:554-556.
34. McKenzie, T., T. Hoshino, T. Tanaka, and N. Sueoka. 1986. The nucleotide sequence of pUB110: some salient features in relation to replication and its regulation. Plasmid 15:93-104.
35. Moller-Jensen, J., R. B. Jensen, and K. Gerdes. 2000. Plasmid and chromosome segregation in prokaryotes. Trends Microbiol, 8:313-320.
36. Moller-Jensen, J., R. B. Jensen, J. Lowe, and K. Gerdes. 2002. Prokaryotic DNA segregation by an actin-like filament, EMBO J. 21:3119-3127.
37. Moran, C. P., N. Lang, S. F. J. LeGrice, G. Lee, M. Stephens, A. L. Sonenshein, J. Pero, and R. Losick. 1982. Nucleotide sequences that signal the initiation of transcription and translation in Bacillus subtilis. Mol. Gen. Genet, 186:339-346.
38. Mori, H., Y. Mori, C. Ichinose, H. Niki, T. Ogura, A. Kato, and S. Hiraga. 1989. Purification and characterization of SopA and SopB proteins essential for F plasmid partitioning. J. Biol. Chem. 264:15535-15541.
39. Niki, H., and S. Hiraga. 1997. Subcellular distribution of actively partitioning F plasmid during the cell division cycle in E. coli. Cell 90:951-957.
40. Nordstrom, K., and S. J. Austin. 1989. Mechanisms that contribute to the stable segregation of plasmids. Annu. Rev. Genet. 23:37-69.
41. Novick, R. P. 1989. Staphylococcal plasmids and their replication. Annu. Rev. Microbiol. 43:537-565.
42. Novick, R. P. 1990. The Staphylococcus as a molecular genetic system, p. 1-37. In R. P. Novick (ed.), Molecular biology of the staphylococci. VCH, New York, N.Y.
43. Paulsen, I. T., N. Firth, and R. A. Skurray. 1997. Resistance to antimicrobial agents other than β-lactams, p. 175-212. In K. B. Crossley and G. L. Archer (ed.), The staphylococci in human disease. Churchill Livingstone, New York, N.Y.
44. Paulsen, I. T., M. T. Gillespie, T. G. Littlejohn, O. Hanvivatvong, S. J. Rowland, K. G. Dyke, and R. A. Skurray. 1994. Characterisation of sin, a potential recombinase-encoding gene from Staphylococcus aureus. Gene 141: 109-114.
45. Rouch, D. A., L. J. Messerotti, L. S. Loo, C. A. Jackson, and R. A. Skurray. 1989. Trimethoprim resistance transposon Tn4003 from Staphylococcus aureus encodes genes for a dihydrofolate reductase and thymidylate synthetase flanked by three copies of IS257. Mol. Microbiol. 3:161-175.
46. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
47. Schenk, S., and R. A. Laddaga. 1992. Improved method for electroporation of Staphylococcus aureus. FEMS Microbiol. Lett. 73:133-138.
48. Shaw, W. V. 1975. Chloramphenicol acetyltransferase from chloramphenicol-resistant bacteria. Methods Enzymol. 43:737-755.
49. Sheehy, R. J., and R. P. Novick. 1975. Studies on plasmid replication. V. Replicative intermediates. J. Mol. Biol. 93:237-253.
50. Surtees, J. A., and B. E. Funnell. 1999. P1 ParB domain structure includes two independent multimerization domains. J. Bacteriol. 181:5898-5908.
51. Surtees, J. A., and B. E. Funnell. 2001. The DNA binding domains of P1 ParB and the architecture of the P1 plasmid partition complex. J. Biol. Chem. 276:12385-12394.
52. Suzuki, M., N. Yagi, and M. Gerstein. 1995. DNA recognition and superstructure formation by helix-turn-helix proteins. Protein Eng. 8:329-338.
53. Swinfield, T. J., L. Janniere, S. D. Ehrlich, and N. P. Minton, 1991. Characterization of a region of the Enterococcus faecalis plasmid pAMβ1 which enhances the segregational stability of pAMβ1-derived cloning vectors in Bacillus subtilis. Plasmid 26:209-221.
54. Tanaka, T., and M. Ogura. 1998. A novel Bacillus natto plasmid pLS32 capable of replication in Bacillus subtilis. FEBS Lett. 422:243-246.
55. Weaver, K. E., D. B. Clewell, and F. An. 1993. Identification, characterization, and nucleotide sequence of a region of Enterococcus faecalis pheromone-responsive plasmid pADI capable of autonomous replication. J. Bacteriol. 175:1900-1909.
56. Weaver, K. E., K. D. Jensen, A. Colwell, and S. I. Sriram. 1996. Functional analysis of the Enterococcus faecalis plasmid pAD1-encoded stability-determinant par. Mol. Microbiol. 20:53-63.
57. Weitao, T., S. Dasgupta, and K. Nordstrom. 2000. Role of the mukB gene in chromosome and plasmid partition in Escherichia coli. Mol. Microbiol. 38: 392-400.
58. Williams, D. R., and C. M. Thomas. 1992. Active partitioning of bacterial plasmids. J. Gen. Microbiol. 138:1-16.
59. Wirth, R., F. Y. An, and D. B. Clewell. 1986. Highly efficient protoplast transformation system for Streptococcus faecalis and a new Escherichia coli-S. faecalis shuttle vector. J. Bacteriol. 165:831-836.
60. Wolf, E., P. S. Kim, and B. Berger. 1997. MultiCoil: a program for predicting two- and three-stranded coiled coils. Protein Sci. 6:1179-1189.