Matrix metalloproteinase activity in urine of patients with renal cell carcinoma leads to degradation of extracellular matrix proteins: Possible use as a screening assay

Journal of Urology

Volumn 169, Issue 4, 2003, Pages 1530-1534

  Sherief, Mahmoud H ^a   Low, Seng Hui ^a   Miura, Masumi ^a   Kudo, Noriko ^a   Novick, Andrew C ^a   Weimbs, Thomas ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Biological; Carcinoma; Extracellular matrix proteins; Kidney; Matrix metalloproteinases; Renal cell; Tumor markers

Indexed keywords

COLLAGEN TYPE 4; FIBRONECTIN; LAMININ; MATRIX METALLOPROTEINASE;

ARTICLE; CANCER DIAGNOSIS; CLINICAL ARTICLE; ENZYME ACTIVITY; HUMAN; KIDNEY CARCINOMA; MICROTITER PLATE ASSAY; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCREENING; URINALYSIS; ZYMOGRAPHY;

EID: 0037376776     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000049201.91150.9d     Document Type: Article

References (18)

1. Landis S. H., Murray, T., Bolden, S. and Wingo, P. A.: Ancer statistics, 1999. CA Cancer J Clin, 49: 8, 1999
2. Hafez, K. S., Fergany, A. F. and Novick, A. C.: Nephron sparing surgery for localized renal cell carcinoma: impact of tumor size on patient survival, tumor recurrence and TNM staging. J Urol, 162: 1930, 1999
3. Cohn, E. B. and Campbell, S. C.: Screening for renal cell carcinoma. In: Renal Cell Carcinoma: Molecular Biology, Immunology, and Clinical Management. Edited by R. M. Bukowski and A. C. Novick. Totowa, New Jersey: Humana Press, pp. 93-110, 2000
4. Muscat, J. E.: The epidemiology of renal cell carcinoma. In: Renal Cell Carcinoma: Molecular Biology, Immunology, and Clinical Management. Edited by R. M. Bukowski and A. C. Novick. Totowa, New Jersey: Humana Press, pp. 3-13, 2000
5. Fergany, A. F., Hafez, K. S. and Novick, A. C.: Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year followup. J Urol, 163: 442, 2000
6. Novick, A. C., Gephardt, G., Guz, B., Steinmuller, D. and Tubbs, R. R.: Long-term follow-up after partial removal of a solitary kidney. N Engl J Med, 325: 1058, 1991
7. Weimbs, T., Low, S. H., Chapin, S. J. and Mostov, K. E.: Apical targeting in polarized epithelial cells: there's more afloat than rafts. Trends Cell Biol, 7: 393, 1997
8. Low, S. H., Miura, M., Roche, P. A., Valdez, A. C., Mostov, K. E. and Weimbs, T.: Intracellular redirection of plasma membrane trafficking after loss of epithelial cell polarity. Mol Biol Cell, 11: 3045, 2000
9. Kleiner, D. E. and Stetler-Stevenson, W. G.: Matrix metalloproteinases and metastasis. Cancer Chemother Pharmacol, 43: S42, 1999
10. Curran, S. and Murray, G. I.: Matrix metalloproteinases in tumour invasion and metastasis. J Pathol, 189: 300, 1999
11. Nagase, H. and Woessner, J. F., Jr.: Matrix metalloproteinases. J Biol Chem, 274: 21491, 1999
12. Chambers, A. F. and Matrisian, L. M.: Changing views of the role of matrix metalloproteinases in metastasis. J Natl Cancer Inst, 89: 1260, 1997
13. Bergers, G. and Coussens, L. M.: Extrinsic regulators of epithelial tumor progression: metalloproteinases. Curr Opin Genet Dev, 10: 120, 2000
14. Lein, M., Jung, K., Laube, C., Hubner, T., Winkelmann, B., Stephan, C. et al: Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma. Int J Cancer, 85: 801, 2000
15. Kugler, A., Hemmerlein, B., Thelen, P., Kallerhoff, M., Radzun, H.-J. and Ringert, R.-H.: Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma. J Urol, 160: 1914, 1998
16. Curry, T. E., Jr. and Osteen, K G: Cyclic changes in the matrix metalloproteinase system in the ovary and uterus. Biol Reprod, 64: 1285, 2001
17. Fuhrman, S. A., Lasky, L. C. and Limas, C.: Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol, 6: 655, 1982
18. Guinan, P., Sobin, L. H., Algaba, F., Badellino, F., Kameyama, S., MacLennan, G. et al: TNM staging of renal cell carcinoma: Workgroup No. 3. Union International Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer, 80: 992, 1997