메뉴 건너뛰기




Volumn 21, Issue 1, 2003, Pages 49-59

Anakinra, a new pharmacotherapeutic approach to treating rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; ETANERCEPT; METHOTREXATE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

EID: 0037374042     PISSN: 07412320     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (28)
  • 1
    • 0025304539 scopus 로고
    • Rheumatoid arthritis: Pathophysiology and implications for therapy
    • Harris ED Jr.: Rheumatoid arthritis: Pathophysiology and implications for therapy. N. Engl. J. Med. 322:1277-1289, 1990.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1277-1289
    • Harris E.D., Jr.1
  • 2
    • 0035932519 scopus 로고    scopus 로고
    • Cytokine pathways and joint inflammation in rheumatoid arthritis
    • Choy EH and Panayi GS: Cytokine pathways and joint inflammation in rheumatoid arthritis. N. Engl. J. Med. 344:907-916, 2001.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 907-916
    • Choy, E.H.1    Panayi, G.S.2
  • 3
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin 1 in disease
    • Dinarello CA: Biologic basis for interleukin 1 in disease. Blood 87:2095-2147, 1996.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 4
    • 0022552224 scopus 로고
    • Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells
    • Dayer JM, De-Rochemontix B, Burrus B, et al.: Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J. Clin. Invest. 77:645-648, 1986.
    • (1986) J. Clin. Invest. , vol.77 , pp. 645-648
    • Dayer, J.M.1    De-Rochemontix, B.2    Burrus, B.3
  • 5
    • 0025713953 scopus 로고
    • Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor
    • Hannum CH, Wilcox CJ, Arend WP, et al.: Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor. Nature 343:336-340, 1990.
    • (1990) Nature , vol.343 , pp. 336-340
    • Hannum, C.H.1    Wilcox, C.J.2    Arend, W.P.3
  • 6
    • 0025787689 scopus 로고
    • Interleukin-1 receptor antagonist - A new member of the interleukin-1 family
    • Arend WP: Interleukin-1 receptor antagonist - A new member of the interleukin-1 family. J. Clin. Invest. 88:1445-1451, 1991.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1445-1451
    • Arend, W.P.1
  • 7
    • 0028810316 scopus 로고
    • Major role for interleukin 1 but not for tumor necrosis factor in early cartilage damage in immune complex in mice
    • van Lent PLEM, van de Loo FAJ, Astrid EM, et al.: Major role for interleukin 1 but not for tumor necrosis factor in early cartilage damage in immune complex in mice. J. Rheumatol. 22:2250-2258, 1995.
    • (1995) J. Rheumatol. , vol.22 , pp. 2250-2258
    • Van Lent, P.L.E.M.1    Van de Loo, F.A.J.2    Astrid, E.M.3
  • 8
    • 0023716725 scopus 로고
    • Comparison of the in vivo inflammatory activities after intra-articular injection of natural and recombinant IL-1 alpha and IL-1 beta in the rabbit
    • Henderson B and Pettipher ER: Comparison of the in vivo inflammatory activities after intra-articular injection of natural and recombinant IL-1 alpha and IL-1 beta in the rabbit. Biochem. Pharmacol. 37:4171-40176, 1988.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 4171-40176
    • Henderson, B.1    Pettipher, E.R.2
  • 9
    • 0031253812 scopus 로고    scopus 로고
    • Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis
    • Ghivizzani SC, Kang R, Georgescu HI, et al.: Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. J. Immunol. 159:3604-3612, 1997.
    • (1997) J. Immunol. , vol.159 , pp. 3604-3612
    • Ghivizzani, S.C.1    Kang, R.2    Georgescu, H.I.3
  • 10
    • 0025254121 scopus 로고
    • Interleukin 1 enhances the development of spontaneous arthritis in MRL/1pr mice
    • Hom JT, Cole H and Bendele AM: Interleukin 1 enhances the development of spontaneous arthritis in MRL/1pr mice. Clin. Immumol. Immunopathol. 55:109-119, 1990.
    • (1990) Clin. Immumol. Immunopathol. , vol.55 , pp. 109-119
    • Hom, J.T.1    Cole, H.2    Bendele, A.M.3
  • 11
    • 0026507611 scopus 로고
    • Protection against cartilage proteoglycan synthesis inhibition by antiinterleukin 1 antibodies in experimental arthritis
    • van de Loo FA, Arntz OJ, Otterness IG and van den Berg WB: Protection against cartilage proteoglycan synthesis inhibition by antiinterleukin 1 antibodies in experimental arthritis. J. Rheumatol. 19:348-356, 1992.
    • (1992) J. Rheumatol. , vol.19 , pp. 348-356
    • Van de Loo, F.A.1    Arntz, O.J.2    Otterness, I.G.3    Van den Berg, W.B.4
  • 12
    • 0023694150 scopus 로고
    • Correlation of plasma interleukin 1 levels with disease activity in rheumatoid arthritis
    • Eastgate JA, Symons JA, Wood NC, et al.: Correlation of plasma interleukin 1 levels with disease activity in rheumatoid arthritis. Lancet ii:706-709, 1988.
    • (1988) Lancet , vol.2 , pp. 706-709
    • Eastgate, J.A.1    Symons, J.A.2    Wood, N.C.3
  • 13
    • 0023914715 scopus 로고
    • Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients: Possible involvement in joint destruction
    • Miyasaka N, Sato K, Goto M, et al.: Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients: Possible involvement in joint destruction. Arthritis Rheum. 31:480-486, 1988.
    • (1988) Arthritis Rheum. , vol.31 , pp. 480-486
    • Miyasaka, N.1    Sato, K.2    Goto, M.3
  • 14
    • 0028891167 scopus 로고
    • Role of interleukin-1 tumor necrosis factor-α and interleukin-6 in cartilage proteoglycan metabolism and destruction: Effect of in-situ blocking in murine antigen and zymosan-induced arthritis
    • van de Loo FAJ, Joosten LAB, van Lent PLEM, et al.: Role of interleukin-1 tumor necrosis factor-α and interleukin-6 in cartilage proteoglycan metabolism and destruction: Effect of in-situ blocking in murine antigen and zymosan-induced arthritis. Arthritis Rheum. 38:164-172, 1995.
    • (1995) Arthritis Rheum. , vol.38 , pp. 164-172
    • Van de Loo, F.A.J.1    Joosten, L.A.B.2    Van Lent, P.L.E.M.3
  • 15
    • 0031787636 scopus 로고    scopus 로고
    • Joint inflammation and cartilage destruction may occur uncoupled
    • van den Berg WB: Joint inflammation and cartilage destruction may occur uncoupled. Springer Semin. Immunopathol. 20:149-164, 1998.
    • (1998) Springer Semin. Immunopathol. , vol.20 , pp. 149-164
    • Van den Berg, W.B.1
  • 17
    • 17444394445 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
    • Bresnihan B, Alvaro-Garcia JM, Cobby M, et al.: Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis-Rheum. 41:2196-2204, 1998.
    • (1998) Arthritis-Rheum. , vol.41 , pp. 2196-2204
    • Bresnihan, B.1    Alvaro-Garcia, J.M.2    Cobby, M.3
  • 18
    • 0034083128 scopus 로고    scopus 로고
    • A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis
    • Jiang Y, Genant HK, Watt I, et al.: A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis. Arthritis Rheum. 43:1001-1009, 2000.
    • (2000) Arthritis Rheum. , vol.43 , pp. 1001-1009
    • Jiang, Y.1    Genant, H.K.2    Watt, I.3
  • 19
    • 0036845130 scopus 로고    scopus 로고
    • Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis
    • Nuki G, Bresnihan B, Moraye BB, et al.: Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis. Arthritis Rheum. 46:2838-2846, 2002.
    • (2002) Arthritis Rheum. , vol.46 , pp. 2838-2846
    • Nuki, G.1    Bresnihan, B.2    Moraye, B.B.3
  • 20
    • 0036190776 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate
    • Cohen S, Hurd E, Cush J, et al.: Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate. Arthritis Rheum. 46:614-624, 2002.
    • (2002) Arthritis Rheum. , vol.46 , pp. 614-624
    • Cohen, S.1    Hurd, E.2    Cush, J.3
  • 21
    • 0013462887 scopus 로고    scopus 로고
    • Kineret™ (anakinra) (recombinant interleukin-1 receptor antagonist): A large placebo controlled efficacy trial of Kineret™ in patients with erosive rheumatoid arthritis
    • Cohen SB, Moreland LW, Cush JJ, et al.: Kineret™ (anakinra) (recombinant interleukin-1 receptor antagonist): A large placebo controlled efficacy trial of Kineret™ in patients with erosive rheumatoid arthritis. Ann. Rheum. Dis. 61(Suppl.): S173, 2002.
    • (2002) Ann. Rheum. Dis. , vol.61 , Issue.SUPPL.
    • Cohen, S.B.1    Moreland, L.W.2    Cush, J.J.3
  • 22
    • 9744227457 scopus 로고    scopus 로고
    • Anakinra (Kineret™) inhibits the progression of radiographically measured joint destruction in rheumatoid arthritis
    • New Orleans, Otober
    • Shergy WJ, Cohen S, Greenwald M, et al.: Anakinra (Kineret™) inhibits the progression of radiographically measured joint destruction in rheumatoid arthritis. Late-breaking abstract presented at the American College of Rheumatology meeting, New Orleans, Otober 24-29, 2002.
    • (2002) American College of Rheumatology Meeting , pp. 24-29
    • Shergy, W.J.1    Cohen, S.2    Greenwald, M.3
  • 23
    • 0001381462 scopus 로고    scopus 로고
    • A safety trial of anakinra: Recombinant interleukin-1 receptor antagonist (IL-1Ra) in a large placebo controlled heterogeneous population of patients with rheumatoid arthritis
    • Fleischman R, Tesser J, Schechtman J, et al.: A safety trial of anakinra: Recombinant interleukin-1 receptor antagonist (IL-1Ra) in a large placebo controlled heterogeneous population of patients with rheumatoid arthritis. Arthritis-Rheum. 44(Suppl.):S84, 2001.
    • (2001) Arthritis-Rheum. , vol.44 , Issue.SUPPL.
    • Fleischman, R.1    Tesser, J.2    Schechtman, J.3
  • 24
    • 0000980044 scopus 로고    scopus 로고
    • The safety of Kineret (anakinra) in high risk patients
    • Schiff M, Hartman S, Devittorio G, et al.: The safety of Kineret (anakinra) in high risk patients (Abstr.). Ann. Rheum. Dis. 61:173, 2002.
    • (2002) Ann. Rheum. Dis. , vol.61 , pp. 173
    • Schiff, M.1    Hartman, S.2    Devittorio, G.3
  • 25
    • 0013463595 scopus 로고    scopus 로고
    • Safety of combination therapy with Kineret™ (anakinra) and etanercept in patients with rheumatoid arthritis
    • Schiff M, Bulpitt K, Weaver A, et al.: Safety of combination therapy with Kineret™ (anakinra) and etanercept in patients with rheumatoid arthritis (Abstr.). Ann. Rheum. Dis. 61(Suppl.):185, 2002.
    • (2002) Ann. Rheum. Dis. , vol.61 , Issue.SUPPL. , pp. 185
    • Schiff, M.1    Bulpitt, K.2    Weaver, A.3
  • 27
    • 0000927987 scopus 로고    scopus 로고
    • A phase I safety study of combination treatment with pegylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) and anakinra (interleukin-1 receptor antagonist, IL-1RA) in patients with rheumatoid arthritis
    • Caldwell JR, Offenberg H, Furst D, et al.: A phase I safety study of combination treatment with pegylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) and anakinra (interleukin-1 receptor antagonist, IL-1RA) in patients with rheumatoid arthritis (Abstr.). Arthritis Rheum. 44(Suppl.):S370, 2001.
    • (2001) Arthritis Rheum. , vol.44 , Issue.SUPPL.
    • Caldwell, J.R.1    Offenberg, H.2    Furst, D.3
  • 28
    • 0013463725 scopus 로고    scopus 로고
    • Preliminary data from a study of Kineret™ (anakinra) in children with juvenile rheumatoid arthritis
    • Reiff A, Porras O, Rudge S, et al.: Preliminary data from a study of Kineret™ (anakinra) in children with juvenile rheumatoid arthritis. Arthritis Rheum. 46(Suppl.):S215, 2002.
    • (2002) Arthritis Rheum. , vol.46 , Issue.SUPPL.
    • Reiff, A.1    Porras, O.2    Rudge, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.