Exercise training alters length dependence of contractile properties in rat myocardium

Journal of Applied Physiology

Volumn 94, Issue 3, 2003, Pages 1137-1144

  Diffee, Gary M ^a   Nagle, Daniel F ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Calcium sensitivity; Cardiac myocytes; Endurance training; Sarcomere length

Indexed keywords

CALCIUM ION; CITRATE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PERMEABILIZATION; CONTROLLED STUDY; ENDURANCE; ENZYME ACTIVITY; EXERCISE; FEMALE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART WEIGHT; NONHUMAN; PLANTARIS MUSCLE; PRIORITY JOURNAL; RAT; RAT STRAIN; SARCOMERE; SITTING; STEADY STATE; TRAINING; TREADMILL EXERCISE;

EID: 0037370921     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00565.2002     Document Type: Article

References (46)

1. Allen DG and Kurihara S. The effects of muscle length on intracellular calcium transients in mammalian cardiac muscle. J Physiol 327: 79-94, 1982.
2. Allen DG and Kentish JC. Calcium concentration in the myoplasm of skinned ferret ventricular muscle following changes in muscle length. J Physiol 407: 489-503, 1988.
3. 2+ sensitivity of skinned cardiac muscle contractility coincident with troponin T-band shifts in the diabetic rat. Circ Res 76: 600-606, 1995.
4. Babu A, Sonnenblick E, and Gulati J. Molecular basis for the influence of muscle length on myocardial performance. Science 240: 74-76, 1988.
5. Bersohn MM and Scheuer J. Effects of physical training on end-diastolic volume and myocardial performance of isolated rat hearts. Circ Res 40: 510-517, 1977.
6. Bhan AK and Scheuer J. Effects of physical training on cardiac myosin ATPase activity. Am J Physiol 228: 1178-1182, 1975.
7. Blomqvist CG and Saltin B. Cardiovascular adaptations to physical training. Annu Rev Physiol 4: 169-189, 1983.
8. 2+ to two regulatory sites on troponin C determine the steep pCa/tension relationship of skeletal muscle. Proc Natl Acad Sci USA 77: 4717-4720, 1980.
9. Di Bello V, Santoro G, Talarico L, Di Muro C, Caputo MT, Giorgi D, Bertini A, Bianchi M, and Giusti C. Left ventricular function during exercise in athletes and in sedentary men. Med Sci Sports Exerc 28: 190-196, 1996.
10. 2+ sensitivity of tension in rat cardiac myocytes. J Appl Physiol 91: 309-315, 2001.
11. Dobesh DP, Konhilas JP, and de Tombe PP. Cooperative activation in cardiac muscle: impact of sarcomere length. Am J Physiol Heart Circ Physiol 282: H1055-H1062, 2002.
12. 2+ mediated through α- and β- adrenoceptors. Circ Res: 247-265, 1988.
13. Fabiato A. Computer programs for calculating total from specified free and free from specified total ionic concentrations in aqueous solutions containing multiple metals or ligands. Methods Enzymol 157: 378-417, 1988.
14. Fitzsimons DP, Bodell PW, Herrick RE, and Baldwin KM. Left ventricular functional capacity in the endurance-trained rodent. J Appl Physiol 69: 309-312, 1990.
15. Fuller EO and Nutter DO. Endurance training in the rat. II. Performance of isolated and intact heart. J Appl Physiol 51: 941-947, 1981.
16. Granzier HL and Irving TC. Passive tension in cardiac muscle: contributions of collagen, titin, microtubules, and intermediate filaments, Biophys J 68: 1027-1044, 1995.
17. Hepp A, Hansis M, Gulch R, and Jacob R. Left ventricular isovolumetric pressure-volume relations, "diastolic tone," and contractility in the rat heart after physical training. Basic Res Cardiol 69: 516-532, 1974.
18. Hibberd MG and Jewell BR. Calcium- and length-dependent force production in rat ventricular muscle. J Physiol 329: 527-540, 1982.
19. 2+ sensitive tension due to partial extraction of C-protein from rat skinned cardiac myocytes and rabbit skeletal muscle fibers. J Gen Physiol 97: 1141-1163, 1991.
20. Jin H, Yang R, Li W, Lu H, Ryan AM, Ogasawara AK, Van Peborgh J, and Paoni NF. Effects of exercise training on cardiac function, gene expression, and apoptosis in rats. Am J Physiol Heart Circ Physiol 279: H2994-H3002, 2000.
21. Konhilas JP, Irving TC, and de Tombe PP. Myofilament calcium sensitivity in skinned rat cardiac trabeculae: role of interfilament spacing. Circ Res 90: 59-65, 2002.
22. Kentish JC, ter Keurs HEDJ, Ricciardi L, Bucx JJJ, and Noble MIM. Comparison between the sarcomere length-force relations of intact and skinned trabeculae from rat right ventricle. Circ Res 58: 755-768, 1986.
23. 2+. Med Sci Sports Exerc 30: 1502-1509, 1998.
24. Laughlin MH, Hale CC, and Novela L. Biochemical characterization of exercise-trained porcine myocardium. J Appl Physiol 7: 229-235, 1991.
25. Levine BD, Lane LD, Buckley JC, Friedman DB, and Blomqvist CG. Left ventricular pressure-volume and Frank-Starling relations in endurance athletes: implications for ortho-static tolerance and exercise performance. Circulation 8: 1016-1023, 1991.
26. 2+ sensitivity of tension in mouse cardiac myocytes expressing skeletal troponin C. J Physiol 483: 131-139, 1995.
27. 2+ sensitivity of tension at short sarcomere length. Circ Res 77: 199-205, 1995.
28. Molé P. Increased contractile potential of papillary muscles from exercise-trained rat hearts. Am J Physiol Heart Circ Physiol 234: H421-H425, 1978.
29. Moore RL and Korzick DH. Cellular adaptations of the myocardium to chronic exercise. Prog Cardiovasc Dis 37: 371-396, 1995.
30. Moore RL, Musch TI, Yelamarty RV, Scaduto RC Jr, Semanchick AM, Elensky M, and JY Cheung. Chronic exercise alters contractility and morphology of isolated rat cardiac myocytes. Am J Physiol Cell Physiol 264: C1180-C1189, 1993.
31. Natali AJ, Wilson LA, Peckham M, Turner DL, Harrison SM, and White E. Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes. J Physiol: 863-875, 2002.
32. Page SG. Measurement of structural parameters in cardiac muscle. In: The Physiological Basis for Starling's Law of the Heart. Amsterdam: Elsevier, 1974, p. 13-25. (CIBA Foundation Symposium 24)
33. Penpargkul S, Malhotra A, and Schaible T. Cardiac contractile proteins and sarcoplasmic reticulum in hearts of rats trained by running. J Appl Physiol 48: 409-413, 1980.
34. Penpargkul S, Repke DI, and Katz AM. Effect of physical training on calcium transport by rat cardiac sarcoplasmic reticulum. Circ Res 40: 134-138, 1977.
35. Schaible TF and Scheuer J. Effects of physical training by running or swimming on ventricular performance of rat hearts, J Appl Physiol 46: 854-860, 1979.
36. Schaible TF and Scheuer J. Cardiac adaptations to chronic exercise. Prog Cardiovasc Dis 27: 297-324, 1985.
37. Srere PA. Citrate synthase. Methods Enzymol 1: 3-5, 1969.
38. Strang KT, Sweitzer NK, Greaser ML, and Moss RL. β-Adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats. Circ Res 7: 542-549, 1994.
39. Sweeney HL and Stull JT. Phosphorylation of myosin in permeabilized mammalian cardiac and skeletal muscle cells. Am J Physiol Cell Physiol 250: C657-C660, 1986.
40. Tibbits G, Koziol BJ, Roberts NK, Baldwin KM, and Barnard RJ. Adaptation of the rat myocardium to endurance training. J Appl Physiol 4: 85-89, 1978.
41. Tibbits GF, Barnard RJ, Baldwin KM, Cugalj N, and Roberts NK. Influence of exercise on excitation-contraction coupling in rat myocardium. Am J Physiol Heart Circ Physiol 240: H472-H480, 1981.
42. Widrick JJ, Romatowski JG, Norenberg KM, Knuth ST, Bain JL, Riley DA, Trappe SW, Trappe TA, Costill DL, and Fitts RH. Functional properties of slow and fast gastrocnemius muscle fibers after a 17-day spaceflight. J Appl Physiol 90: 2203-2211, 2001.
43. Wisloff U, Loennechen JP, Falck G, Beisvag V, Currie S, Smith G, and Ellingsen O. Increased contractility and calcium sensitivity in cardiac myocytes isolated from endurance trained rats. Cardiovasc Res 50: 495-508, 2001.
44. Woodiwiss AJ and Norton GR. Exercise-induced cardiac hypertrophy associated with an increased myocardial compliance. J Appl Physiol 78: 1303-1311, 1995.
45. Wolff MR, Buck SH, Stoker SW, Greaser ML, and Mentzer RM. Myofibrillar calcium sensitivity of isometric tension is increased in human dilated cardiomyopathies. J Clin Invest 98: 167-176, 1996.
46. Zhang R, Zhao J, Mandveno A, and Potter JD. Cardiac troponin I phosphorylation increases the rate of cardiac muscle relaxation. Circ Res 76: 1028-1035, 1995.