Wasp venom blocks central cholinergic synapses to induce transient paralysis in cockroach prey

Journal of Neurobiology

Volumn 54, Issue 4, 2003, Pages 628-637

  Haspel, G ^a   Libersat, F ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Ampulex compressa; Cockroach; Nicotinic receptor; Venom; Wasp

Indexed keywords

NICOTINE; WASP VENOM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYNAPSE; CHOLINERGIC SYSTEM; CHOLINERGIC TRANSMISSION; COCKROACH; CONTROLLED STUDY; EVOKED RESPONSE; EVOKED SOMATOSENSORY RESPONSE; FLACCID PARALYSIS; GANGLION; GROOMING; INSECT STING; ISOTOPE LABELING; LETHARGY; MOTONEURON; NERVE CELL; NONHUMAN; POSTSYNAPTIC INHIBITION; POSTSYNAPTIC POTENTIAL; PREY; PRIORITY JOURNAL; WASP;

ACTION POTENTIALS; ANIMALS; BEHAVIOR, ANIMAL; CARBACHOL; CHOLINERGIC AGONISTS; CHOLINERGIC ANTAGONISTS; COCKROACHES; EVOKED POTENTIALS, MOTOR; GANGLIA; INSECT BITES AND STINGS; PARALYSIS; PERIPLANETA; RECEPTORS, CHOLINERGIC; SYNAPTIC TRANSMISSION; TIME FACTORS; TUBOCURARINE; WASP VENOMS; WASPS;

EID: 0037369203     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10195     Document Type: Article

References (34)

1. Adams ME. 1996. Neurotoxins. Trends Neurosci Neurotoxin Supplement.
2. Beard R. 1952. The toxicology of Harbrobracon venom: a study of a natural insecticide. Conn Agric Exp Sta New Haven Bull 562:1-27.
3. Blagburn JM, Beadle DJ, Sattelle DB. 1985. Development of synapses between identified sensory neurones and giant interneurones in the cockroach Periplaneta americana. J Embryol Exp Morphol 86:227-246.
4. Blagburn JM, Sattelle DB. 1987. Nicotinic acetylcholine receptors on a cholinergic nerve terminal in the cockroach, Periplaneta americana. J Comp Physiol A 161:215-225.
5. Callec JJ, David JA, Sattelle DB. 1982. Ionophoresis application of acetylcholine on to the dendrites of an identified giant interneuron (GI1) in the cockroach Periplaneta americana. J Insect Physiol 28:1003-1008.
6. Callec JJ, Sattelle DB. 1973. A simple technique for monitoring the synaptic actions of pharmacological agents. J Exp Biol 59:725-738.
7. David JA, Pitman RM. 1996. Muscarinic receptors activation modulates ligand-gated ion channels via changes in intracellular calcium. Proc R Soc Lond B 263:469-474.
8. Eldefrawi AT, Eldefrawi ME, Konno K, Mansour NA, Nakanishi K. 1988. Structure and synthesis of a potent glutamate receptor antagonist in wasp venom. Proc Natl Acad Sci USA 85:4910-4913.
9. Ferber M, Consoulas C, Gnatzy W. 1999. Digger wasp versus cricket: immediate actions of the predator's paralytic venom on the CNS of the prey. J Neurobiol 38:323-337.
10. Ferber M, Horner M, Cepok S, Gnatzy W. 2001. Digger wasp versus cricket: mechanisms underlying the total paralysis caused by the predator's venom. J Neurobiol 47:207-222.
11. Fouad K, Libersat F, Rathmayer W. 1994. The venom of the cockroach-hunting wasp Ampulex compressa changes motor thresholds: a novel tool for studying the neural control of arousal? Zool 98:23-34.
12. Fouad K, Libersat F, Rathmayer W. 1996. Neuromodulation of the escape behavior of the cockroach Periplaneta americana by the venom of the parasitic wasp Ampulex compressa. J Comp Physiol A 178:91-100.
13. Fourtner C, Kaars C. 1990. Anatomy of the central nervous system and its usefulness as a model for neurobiology. In: Huber I, Masler E, Rao B. editors. Cockroaches as models for neurobiology: applications in biomedical research. Boca Raton, FL: CRC Press, Inc., p 65-87.
14. Gnatzy W, Otto D. 1996. Digger wasp vs. cricket: application of the paralytic venom by the predator and changes in behavioral reactions of the prey after being stung. Naturwissenschaften 83:467-470.
15. Gundelfinger ED. 1992. How complex is the nicotinic receptor system of insects? Trends Neurosci 15(6):206-211.
16. Hue B, Callec J. 1990. Electrophysiology and pharmacology of synaptic transmission in the central nervous system of the cockroach. In: Huber I, Masler E, Rao B. editors. Cockroaches as models for neurobiology: applications in biomedical research. Boca Raton, FL: CRC Press, Inc., p 149-168.
17. Libersat F, Haspel G, Casagrand J, Fouad K. 1999. Localization of the site of effect of a wasp's venom in the cockroach escape circuitry. J Comp Physiol A 184:333-345.
18. Pearson KG, Iles JF. 1971. Innervation of coxal depressor muscles in the cockroach, Periplaneta americana. J Exp Biol 54:215-232.
19. Piek T. 1982. Delta-Philanthotoxin, a semi-irreversible blocker of ion-channels. Comp Biochem Physiol C 72:311-315.
20. Piek T. 1990. Neurotoxins from venoms of the Hymenoptera - twenty-five years of research in Amsterdam. Comp Biochem Physiol C 96:223-233.
21. Piek T, Hue B. 1989. Philanthotoxins, a new class of neuroactive polyamines, block nicotinic transmission in the insect CNS. Comp. Biochem Physiol C 93:403-406.
22. Piek T, Hue B, Lind A, Mantel P, Van Marle J, Visser JH. 1989. The venom of Ampulex compressa - effects on behaviour and synaptic transmission of cockroaches. Comp Biochem Physiol C 92:175-183.
23. Piek T, Hue B, Mony L, Nakajima T, Pelhate M, Yasuhara T. 1987. Block of synaptic transmission in insect CNS by toxins from the venom of the wasp Megascolia flavifrons (Fab.). Comp Biochem Physiol C 87:287-295.
24. Piek T, Spanjer W. 1986. Chemistry and pharmacology of solitary wasp venoms. In: Piek T, editor. Venoms of the Hymenoptera. London: Academic Press. p 161-308.
25. Piek T, Veenendaal RL, Mantel P. 1982. The pharmacology of Microbracon venom. Comp Biochem Physiol C 72:303-309.
26. Rathmayer W. 1978. Venoms of Sphecidae, Pompilidae, Mutillidae, and Bethylidae. In: Bettini S, editor. Handbook of experimental pharmacology. Heidelberg: Springer Verlag, p 661-690.
27. Sattelle DB. 1985. Acetylcholine receptors. In: G Kerkut, L Gilbert, G Kerkut, L Gilbert, editors. Comprehensive insect physiology, biochemistry and pharmacology. Oxford: Pergamon, p 395-434.
28. Sattelle DB, McClay AS, Dowson RJ, Callec JJ. 1976. The pharmacology of an insect ganglion: actions of carbamylcholine and acetylcholine. J Exp Biol 64:13-23.
29. Steiner A. 1986. Stinging behaviour of solitary wasps. In: Piek T, editor. Venoms of the Hymenoptera. London: Academic Press, p 63-159.
30. Tornoe C, Bai D, Holden Dye L, Abramson SN, Sattelle DB. 1995. Actions of neurotoxins (bungarotoxins, neosurugatoxin and lophotoxins) on insect and nematode nicotinic acetylcholine receptors. Toxicon 33:411-424.
31. Trimmer BA, Weeks JC. 1989. Effects of nicotinic and muscarinic agents on an identified motoneurone and its direct afferent inputs in larval manduca sexta. J Exp Biol 144:303-337.
32. Trimmer BA, Weeks JC. 1993. Muscarinic acetylcholine receptors modulate the excitability of an identified insect motoneuron. J Neurophysiol 69:1821-1836.
33. Weisel-Eichler A, Haspel G, Libersat F. 1999. Venom of a parasitoid wasp induces prolonged grooming in the cockroach. J Exp Biol 202:957-964.
34. Williams FX. 1942. Ampulex compressa (Fabr.), a cockroach-hunting wasp introduced from New Caledonia into Hawaii. Proc Haw Ent Soc 11:221-233.