Nuclear localization of alkaline phosphatase in cultured human cancer cells

Medical Electron Microscopy

Volumn 36, Issue 1, 2003, Pages 47-51

  Yamamoto, Koji ^a   Awogi, Takumi ^a   Okuyama, Keiji ^a   Takahashi, Nobuo ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

ALPase; Cell cycle; Chromosome; Electron microscopy; Nucleolus

Indexed keywords

ALKALINE PHOSPHATASE;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL NUCLEUS; CELL PROLIFERATION; CELL STRAIN; CELLULAR DISTRIBUTION; CHROMOSOME; CONTROLLED STUDY; CYTOPLASM; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME LOCALIZATION; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTERPHASE; LIVER CELL CARCINOMA; MELANOMA CELL; MITOSIS; NUCLEOLUS; PANCREAS CARCINOMA; PRIORITY JOURNAL;

ALKALINE PHOSPHATASE; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL NUCLEOLUS; CELL NUCLEUS; CYTOPLASM; HISTOCYTOCHEMISTRY; HUMANS; LIVER NEOPLASMS; MELANOMA; MICROSCOPY, ELECTRON; MITOSIS; NEOPLASMS; PANCREATIC NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0037366268     PISSN: 09184287     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007950300006     Document Type: Article

References (27)

1. Tokumitsu S, Tokumitsu K, Fishman WH (1981) Intracellular alkaline phosphatase activity in cultured human cancer cells. Histochemistry 73:1-13
2. Tokumitsu S, Fishman WH (1983) Alkaline phosphatase biosynthesis in the endoplasmic reticulum and its transport through the Golgi apparatus to the plasma membrane: cytochemical evidence. J Histochem Cytochem 31:647-655
3. Wetzel BK, Spicer SS, Horn RG (1967) Fine structural localization of acid and alkaline phosphatases in cells of rabbit blood and bone marrow. J Histochem Cytochem 15:311-334
4. Mori S, Nagano M (1985) Electron-microscopic cytochemistry of alkaline-phosphatase activity in endothelium, pericytes and oligodendrocytes in the rat brain. Histochemistry 82:225-231
5. Sasaki M, Fishman WH (1973) Ultrastructural studies on Regan and non-Regan isoenzymes of alkaline phosphatase in human ovarian cancer cells. Cancer Res 33:3008-3018
6. Griffin MJ, Cox RP, Grujic N (1967) A chemical method for the isolation of HeLa cell nuclei and the nuclear localization of HeLa cell alkaline phosphatase. J Cell Biol 33:200-203
7. Lewinson D, Toister Z, Silbermann M (1982) Quantitative and distributional changes in the activity of alkaline phosphatase during the maturation of cartilage. J Histochem Cytochem 30:261-269
8. Ishizeki K, Takigawa M, Nawa T, Suzuki F (1996) Mouse Meckel's cartilage chondrocytes evoke bone-like matrix and further transform into osteocyte-like cells in culture. Anat Rec 245:25-35
9. Sasaki T, Amizuka N, Irie K, Ejiri S, Ozawa H (2000) Localization of alkaline phosphatase and osteopontin during matrix mineralization in the developing cartilage of coccygeal vertebrate. Arch Histol Cytol 63:271-284
10. Vergnes HA, Brisson-Lougarre A, Grozdea JG, Blum GC, Kihn Y, Sevely J (1992) Nuclear localization and characterization of alkaline phosphatase in neutrophils from normal controls and pregnant women. Am J Hematol 39:249-256
11. Slor H, Bustan H (1973) Alkaline phosphatase activity in relation to DNA synthesis in synchronized HeLa S3 cells. Experientia (Basel) 29:1214-1215
12. Mayahara H, Hirano H, Saitoh T, Ogawa K (1967) The new lead citrate method for the ultrachemical demonstration of activity of non-specific alkaline phosphatase. Histochemie (Paris) 11:88-96
13. Raška I, Ochs RL, Salamin-Michel L (1990) Immunocytochemistry of the nucleus. Electron Microsc Rev 3:301-353
14. Seargeant LE, Stinson RA (1979) Evidence that three structural genes code for human alkaline phosphatase. Nature (Lond) 281:152-154
15. McKenna MJ, Hamilton TA, Sussaman HH (1979) Comparison of human alkaline phosphatase isoenzymes. Structural evidence for three protein classes. Biochem J 181:67-73
16. Henthorn PS, Raducha M, Edwards YH, Weiss MJ, Slaughter C, Lafferty MA, Harris H (1987) Nucleotide and amino acid sequences of human intestinal alkaline phosphatase: close homology to placental alkaline phosphatase. Proc Natl Acad Sci USA 84:1234-1238
17. Meyer JL, Reddi AH (1985) Changes in pyrophosphatase activity during the de novo mineralization associated with cartilage and bone formation. Arch Biochem Biophys 242:532-539
18. Marinozzi V (1964) Cytochemie ultrastructurale du nucleole-RNA et proteines intranucleolaires. J Ultrastruct Res 10:433-456
19. Granboulan N, Granboulan P (1965) Cytochemie ultrastructurale du nucleole. II. Etude des sites de synthese du RNA dans le nucleole et le noyau. Exp Cell Res 38:604-619
20. Henderson AA, Warburton D, Atwood KC (1972) Location of ribosomal DNA in the human chromosome complement. Proc Natl Acad Sci USA 69:3394-3398
21. Hsu TC, Spirito SE, Pardue ML (1975) Distribution of 18 + 28S ribosomal genes in mammalian genomes. Chromosoma (Berl) 53:25-36
22. Loftus BM, Gilmartin LG, O'Brien MJ, Carney DN, Dervan PA (1990) Intratubular germ cell neoplasia of the testis: identification by placental alkaline phosphatase immunostaining and argyrophilic nucleolar organizer region quantification. Hum Pathol 21:941-948
23. Goodpasture C, Bloom SE (1975) Visualization of nucleolar organizer regions in mammalian chromosomes using silver staining. Chromosoma (Berl) 53:37-50
24. 3H] uridine incorporation in nucleic acids. Exp Cell Res 100:88-94
25. Wachtler F, Hartung H, Devictor M, Wiegant J, Stahl A, Schwarzacher HG (1989) Ribosomal DNA is located and transcribed in the dense fibrillar component of human Sertoli cell nucleoli. Exp Cell Res 184:61-71
26. Wachtler F, Mosgöller M, Schwarzacher HG (1990) Electron microscopic in situ hybridization and autoradiography: localization and transcription of rDNA in human lymphocyte nucleoli. Exp Cell Res 187:346-348
27. Wachtler F, Stahl A (1993) The nucleolus: a structural and functional interpretation. Micron 24:473-505