Intraoperative mitomycin C 0.02% for pterygium: Effect of duration of application on recurrence rate

Cornea

Volumn 22, Issue 2, 2003, Pages 102-104

  Avisar, Rahamim ^a   Gaton, Dan D ^a,b   Loya, Nisim ^a,b   Appel, Itiel ^a   Weinberger, Dov ^a,b  

^a RABIN MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Fibrovascular tissue; Limbus; Mitomycin C; Pterygium

Indexed keywords

MITOMYCIN C; ANTINEOPLASTIC ANTIBIOTIC; MITOMYCIN;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORNEA LIMBUS; DRUG EFFICACY; EXCISION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PEROPERATIVE CARE; PRIORITY JOURNAL; PTERYGIUM; RECURRENCE RISK; SINGLE DRUG DOSE; TIME; COMPARATIVE STUDY; METHODOLOGY; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; RECURRENT DISEASE; SAFETY; TREATMENT OUTCOME;

ADULT; AGED; ANTIBIOTICS, ANTINEOPLASTIC; COMBINED MODALITY THERAPY; FEMALE; HUMANS; INTRAOPERATIVE CARE; MALE; MIDDLE AGED; MITOMYCIN; PROSPECTIVE STUDIES; PTERYGIUM; RECURRENCE; SAFETY; TIME FACTORS; TREATMENT OUTCOME;

EID: 0037363574     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003226-200303000-00003     Document Type: Article

References (23)

1. Frucht-Pery J, Ilsar M, Hemo I. Single dosage of mitomycin C for prevention of recurrent pterygium: preliminary report. Cornea 1994; 13:411-3.
2. Mastropasqua L, Carpineto P, Ciancaglini M, et al. Effectiveness of intraoperative mitomycin C in the treatment of recurrent pterygium. Ophthalmologica 1994;208:247-9.
3. Cano-Perra J, Diaz-Llopis M, Maldonado MJ. et al. Prospective trial of intraoperative mitomycin C in the treatment of primary pterygium. Br J Ophthalmol 1995;79:439-41.
4. Heiligenhaus A, Akova Y, Lung E, et al. Pterygium excision with intraoperative administration of low dosage mitomycin C. Ophthalmologe 1995;92:458-62.
5. Frucht-Pery J, Siganos CS, Ilsar M. Intraoperative application of topical mitomycin C for pterygium surgery. Ophthalmology 1996;103:674-77.
6. Mastropasqua L, Carpineto P, Ciancaglini M, et al. Long-term results of intraoperative mitomycin C in the treatment of recurrent pterygium. Br J Ophthalmol 1996;80:288-91.
7. Helal M, Messiha N, Amayen A. Intraoperative mitomycin C versus postoperative topical mitomycin C drops for the treatment of pterygium. Ophthalmol Surg Lasers 1996;27:674-8.
8. Demirok A, Simsek S, Cinal A, et al. Intraoperative application of mitomycin C in the surgical treatment of pterygium. Eur J Ophthalmol 1998;8:153-6.
9. Manning CA, Kloess PM, Diaz MD, et al. Intraoperative mitomycin C in primary pterygium excision. A prospective randomized trial. Ophthalmology 1997;104:844-8.
10. Cardillo JA, Alves MR, Ambrosio LE, et al. Single intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery. Ophthalmology 1995;102:1949-52.
11. Caliskan S, Orhan M, Irkec M. Intraoperative and postoperative use of mitomycin C in the treatment of primary pterygium. Ophthalmic Surg Lasers 1996;27:600-4.
12. Rubinfeld RS, Stein RM. Topical mitomycin C for pterygia: is single application appropriate? Ophthalmic Surg Lasers 1997;28:662-9.
13. Lam DSC, Wong AKK, Fan DSP, et al. Intraoperative mitomycin C to prevent recurrence of pterygium after excision: a 30-month follow-up study. Ophthalmology 1998;105:901-5.
14. Manning CA, Kloess PM, Diaz MD, et al. Intraoperative mitomycin in primary pterygium excision: a prospective, randomized trial. Ophthalmology 1997;104:844-8.
15. Panda A, Das GK, Tuli SW, et al. Randomized trial of intraoperative mitomycin C in surgery for pterygium. Am J Ophthalmol 1998;125:59-63.
16. Yamamoto T, Varani J, Soong KH. et al. Effects of 5-fluorouracil and mitomycin C on cultured rabbit subconjunctival fibroblasts. Ophthalmology 1990;97:1204-10.
17. Jampel HD. Effect of brief exposure to mitomycin C on viability and proliferation of cultured human Tenon's capsule fibroblasts. Ophthalmology 1992;99:1471-6.
18. Rubinfeld RS, Pfister RR, Stein RM, et al. Serious complications of topical mitomycin C after pterygium surgery. Ophthalmology 1992; 99:1647-54.
19. Fujitani A, Hayasaka S, Shibuya Y, et al. Comeoscleral ulceration and corneal perforation after pterygium excision and topical mitomycin C therapy. Ophthalmologica 1993;207:162-4.
20. Dougherty PJ, Hardten DR, Lindstrom RL. Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin C. Cornea 1996;15:537-40.
21. Tsai YY, Lin JM. Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature. Cornea 2002;21:227-9.
22. Gilman AG, Rall TW, Nies AS, et al. Antineoplastic agents. In: Goodman and Gilman's the pharmacological basis of therapeutics, 8th ed. New York: Pergamon Press, 1990;1247-8.
23. Hirst LW, Sebban A, Chant D. Pterygium recurrence time. Ophthalmology 1994;101:755-8.