Influence of hepatitis C virus coinfection on failure of HIV-infected patients receiving highly active antiretroviral therapy to achieve normal serum β2microglobulin levels

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 22, Issue 3, 2003, Pages 194-196

  Garcia Garcia J A ^a   Mira, J A ^a   Fernandez Rivera J ^a   Ramos, A J ^a   Vargas, J ^a   Macias J ^a   Pineda, J A ^a  

^a HOSPITAL UNIVERSITARIO DE VALME   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MICROBIAL KINETICS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEROTYPE; TREATMENT FAILURE; VIRUS IMMUNITY;

EID: 0037362611     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-003-0888-4     Document Type: Article

References (14)

1. Pantaleo G, Graziosi C, Fauci AS (1993) The immunopathogenesis of human immunodeficiency virus infection. N Engl J Med 328:327-335
2. Fauci AS (1996) Host factors and the pathogenesis of HIV-induced disease. Nature 384:529-534
3. Copeland KTF, Heeney JL (1996) T helper cell activation and human retroviral pathogenesis. Microbiol Rev 60:722-742
4. Graham NM (1996) The role of immunologic and viral markers in predicting clinical outcome in HIV infection. AIDS 10 (Suppl 5):21-25
5. Saves M, Morlat P, Chene G, Peuchant E, Pellegrin I, Bonnet F, Bernard N, Lacoste D, Salamon R, Beylot J (2001) Prognostic value of plasma markers of immune activation in patients with advanced HIV disease treated by combination antiretroviral therapy. Clin Immunol 99:347-352
6. Aukrust P, Liabakk NB, Müller F, Lien E, Espevik T, Froland SS (1994) Serum levels of tumor necrosis factor (TNF)-α and soluble TNF receptors in human immunodeficiency virus type 1 infection - correlations to clinical, immunologic, and virologic parameters. J Infect Dis 169:420-424
7. Stein DS, Lyles RH, Graham NMH, Tassoni CJ, Margolik JB, Phair JP, Rinaldo C, Detels R, Saah A, Bilello J (1997) Predicting clinical progression or death in subjects with early-stage human immunodeficiency virus (HIV) infection: a comparative analysis of quantification of HIV RNA, soluble tumor necrosis factor type II receptor, neopterin and β2microglobulin. J Infect Dis 176:1161-1167
8. Lifson AR, Hessol NA, Buchbinder SP, O'Malley PM, Barnhart L, Segal M, Katz MH, Holmberg SD (1992) Serum β2microglobulin and prediction of progression to ADS in HIV infection. Lancet 339:1436-1440
9. Macías J, Leal M, Delgado J, Pineda JA, Muñoz J, Relimpio F, Rubio A, Rey C, Lissen E (2001) Usefulness of route of transmission, absolute CD8+ T-cell counts, and levels of serum tumor necrosis factor alpha as predictors of survival of HIV-1-infected patients with very low CD4+ T-cell counts. Eur J Clin Microbiol Infect Dis 20:253-259
10. Franco JM, Rubio A, Rey C, Leal M, Macías J, Pineda JA, Sánchez B, Sánchez-Quijano A, Núñez-Roldán A, Lissen E (1999) Reduction of immune system activation in HIV-1-infected patients undergoing HAART. Eur J Clin Microbiol Infect Dis 18:733-736
11. Aukrust P, Muller F, Lien E, Nordoy I, Liabakk NB, Espevik T, Froland SS (1999) Tumor necrosis factor (TNF) system levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy: persistent TNF activation is associated with virologic and immunologic treatment failure. J Infect Dis 179:74-82
12. Malaguarnera M, Restuccia S, Di Fazio I, Zoccolo AM, Trovato BA, Pistone G (1997) Serum beta2-microglobulin in chronic hepatitis C. Dig Dis Sci 42 (Suppl 4):762-766
13. Zang L, Ramratnam B, Tenner-Racz K, He Y, Vesanen M, Lewin S, Talal A, Racz P, Perelson AS, Korber BT, Markowitz M, Ho DD, Guo Y, Duran M, Hurley A, Tsay J, Huang YC, Wang CC (1999) Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy. N Engl J Med 340:1605-1613
14. Puppo F, Torre F, Contini P, Ghio M, Brenci S, Brizzolara R, Sinelli N, Campo N, Indiveri F, Picciotto A (2000) Soluble β2-μ-associated and β2-μ-free HLA class I heavy chain serum levels in interferon-α nonresponder chronic hepatitis C patients. Markers of immune activation, and response to antiviral retreatment. J Clin Immunol 20:486-490