An fMRI investigation of hand representation in paraplegic humans

Neurorehabilitation and Neural Repair

Volumn 17, Issue 1, 2003, Pages 37-47

  Turner, Jessica A ^a,b,d   Lee, Jae S ^a,b   Schandler, Steven L ^a,b,c   Cohen, Michael J ^a,b  

^a Long Beach V Aff Hlthcare Syst   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CHAPMAN UNIVERSITY   (United States)

^d VA LONG BEACH HEALTHCARE SYSTEM   (United States)

Author keywords

Cortical reorganization; Spinal cord injury

Indexed keywords

ADULT; ARTICLE; BRAIN MAPPING; CLINICAL ARTICLE; FUNCTIONAL ASSESSMENT; HAND FUNCTION; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARAPLEGIA; SPINAL CORD INJURY; HAND; INNERVATION; MIDDLE AGED; MOTOR CORTEX; MOVEMENT (PHYSIOLOGY); NERVE CELL PLASTICITY; PATHOPHYSIOLOGY; PHYSIOLOGY; SOMATOSENSORY CORTEX;

ADULT; HAND; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; MOTOR CORTEX; MOVEMENT; NEURONAL PLASTICITY; PARAPLEGIA; SOMATOSENSORY CORTEX;

EID: 0037361085     PISSN: 08884390     EISSN: None     Source Type: Journal    
DOI: 10.1177/0888439002250443     Document Type: Article

References (43)

1. Cohen LG, Ziemann U, Chen R, et al. Studies of neuroplasticity with transcranial magnetic stimulation. J Clin Neurophysiol 1998;15:305-24.
2. Donoghue JP. Plasticity of adult sensorimotor representations. Curr Opin Neurobiol 1995;5:749-54.
3. Cohen LG, Bandinelli S, Findley TW, Hallett M. Motor reorganization after upper limb amputation in man. A study with focal magnetic stimulation. Brain 1991;114:615-27.
4. Flor H, Elbert T, Muhlnickel W, Pantev C, Wienbruch C, Taub E. Cortical reorganization and phantom phenomena in congenital and traumatic upper-extremity amputees. Exp Brain Res 1998;119:205-12.
5. Fuhr P, Cohen LG, Dang N, et al. Physiological analysis of motor reorganization following lower limb amputation. Electroencephalogr Clin Neurophysiol 1992;85:53-60.
6. Knecht S, Henningsen H, Elbert T, et al. Cortical reorganization in human amputees and mislocalization of painful stimuli to the phantom limb. Neurosci Lett 1995;201:262-4.
7. Montoya P, Ritter K, Huse E, et al. The cortical somatotopic map and phantom phenomena in subjects with congenital limb atrophy and traumatic amputees with phantom limb pain. Eur J Neurosci 1998;10:1095-102.
8. Pascual-Leone A, Peris M, Tormos JM, Pascual AP, Catala MD. Reorganization of human cortical motor output maps following traumatic forearm amputation. Neuroreport 1996;7:2068-70.
9. Reoricht S, Meyer BU, Niehaus L, Brandt SA. Long-term reorganization of motor cortex outputs after arm amputation. Neurology 1999;53:106-11.
10. Elbert T, Pantev C, Wienbruch C, Rockstroh B, Taub E. Increased cortical representation of the fingers of the left hand in string players. Science 1995;270:305-7.
11. Godde B, Spengler F, Dinse HR. Associative pairing of tactile stimulation induces somatosensory cortical reorganization in rats and humans. Neuroreport. 1996;8:281-5.
12. Hamdy S, Rothwell JC, Aziz Q, Singh KD, Thompson DG. Long-term reorganization of human motor cortex driven by short-term sensory stimulation. Nat Neurosci 1998;1:64-8.
13. Ramachandran VS, Stewart M, Rogers-Ramachandran DC. Perceptual correlates of massive cortical reorganization. Neuroreport 1992;3:583-86.
14. Ramachandran VS, Rogers-Ramachandran D, Cobb S. Touching the phantom limb [letter]. Nature 1995;377:489-90.
15. Ramachandran VS, Hirstein W. The perception of phantom limbs. The D. O. Hebb lecture. Brain 1998;121:1603-30.
16. Birbaumer N, Lutzenberger W, Montoya P, et al. Effects of regional anesthesia on phantom limb pain are mirrored in changes in cortical reorganization. J Neurosci 1997;17:5503-8.
17. Bruehlmeier M, Dietz V, Leenders KL, Roelcke U, Missimer J, Curt A. How does the human brain deal with a spinal cord injury? Eur J Neurosci 1998;10:3918-22.
18. Green JB, Sora E, Bialy Y, Ricamato A, Thatcher RW. Cortical sensorimotor reorganization after spinal cord injury: an electroencephalographic study. Neurology 1998;50:1115-21.
19. Green JB, Sora E, Bialy Y, Ricamato A, Thatcher RW. Cortical motor reorganization after paraplegia: an EEG study. Neurology 1999;53:736-43.
20. Moore CI, Stern CE, Dunbar C, Kostyk SK, Gehi A, Corkin S. Referred phantom sensations and cortical reorganization after spinal cord injury in humans. Proc Natl Acad Sci U S A 2000;97:14703-8.
21. Lotze M, Erb M, Flor H, Huelsmann E, Godde B, Grodd W. fMRI evaluation of somatotopic representation in human primary motor cortex. Neuroimage 2000;11:473-81.
22. Maillard L, Ishil K, Bushara K, Waldvogel D, Schulman AE, Hallett M. Mapping the basal ganglia: fMRI evidence for somatotopic representation of face, hand, and foot. Neurology 2000;55:377-83,
23. Yetkin FZ, Papke RA, Mark LP, Daniels DL, Mueller WM, Haughton VM. Location of the sensorimotor cortex: functional and conventional MR compared. AJNR. Am J Neuroradiol 1995;16:2109-13.
24. Yetkin FZ, Mueller Wm, Hammeke TA, Morris GL, Haughton VM. Functional magnetic resonance imaging mapping of the sensorimotor cortex with tactile stimulations. Neurosurgery 1995;36:921-5.
25. Bittar RG, Ptito A, Reutens DC. Somatosensory representation in patients who have undergone hemispherectomy: a functional magnetic resonance imaging study. J Neurosurg 2000;92:45-51.
26. Hammeke TA, Yetkin FZ, Mueller WM, et al. Functional magnetic resonance imaging of somatosensory stimulation. Neurosurgery 1994;35:677-81.
27. Turner R, Howseman A, Rees GE, Josephs O, Friston K. Functional magnetic resonance imaging of the human brain: data acquisition and analysis. Exp Brain Res 1998;123:5-12.
28. Friston KJ, Holmes AP, Worsley KJ. How many subjects constitute a study? Neuroimage 1999;10:1-5.
29. Friston KJ, Holmes AP, Price CJ, Beuchel C, Worsley KJ. Multisubject fMRI studies and conjunction analyses. Neuroimage 1999;10:385-96.
30. Rao SM, Bandettini PA, Binder JR, et al. Relationship between finger movement rate and functional magnetic resonance signal change in human primary motor cortex. J Cereb Blood Flow Metab 1996;16:1250-4.
31. Byl NN, Merzenich MM, Cheung S, Bedenbaugh P, Nagarajan SS, Jenkins WM. A primate model for studying focal dystonia and repetitive strain injury: effects on the primary somatosensory cortex. Phys Ther 1997;77:269-84.
32. Bara-Jimenez W, Catalan MJ, Hallett M, Gerloff C. Abnormal somatosensory homunculus in dystonia of the hand. Ann Neurol 1998;44:828-31.
33. Byl NN, Melnick M. The neural consequences of repetition: clinical implications of a learning hypothesis. J Hand Ther 1997;10:160-74.
34. Sabbah P, de Schonen S, Leveque C, et al. Sensorimotor cortical activity in patients with complete spinal cord injury: a functional magnetic resonance imaging study. J Neurotrauma 2002;19:53-60.
35. Mikulis DJ, Jurkiewicz MT, McIlroy WE, et al. Adaptation in the motor cortex following cervical spinal cord injury. Neurology 2002;58:794-801.
36. McGonigle DJ, Howseman AM, Athwal BS, Friston KJ, Frackowiak RS, Holmes AP. Variability in fMRI: an examination of intersession differences. Neuroimage 2000;11:708-34.
37. Borsook D, Becerra L, Fishman S, et al. Acute plasticity in the human somatosensory cortex following amputation. Neuroreport 1998;9:1013-7.
38. Flor H, Elbert T, Knecht S, et al. Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 1995;8:482-4.
39. Lee M, Reddy H, Johansen-Berg H, et al. The motor cortex shows adaptive functional changes to brain injury from multiple sclerosis. Ann Neurol 2000;47:606-13.
40. Rossini PM, Caltagirone C, Castriota-Scanderbeg A, et al. Hand motor cortical area reorganization in stroke: a study with fMRI, MEG and TCS maps. Neuroreport 1998;9:2141-6.
41. Doetsch GS. Perceptual significance of somatosensory cortical reorganization following peripheral denervation. Neuroreport 1998;9:R29-35.
42. Sherman RA, Phantom pain. New York: Plenum; 1997.
43. Harris JA. Cortical origin of pathological pain. Lancet 1999;354:1464-6.