Lymecycline in the treatment of acne: An efficacious, safe and cost-effective alternative to minocycline

European Journal of Dermatology

Volumn 13, Issue 2, 2003, Pages 130-135

  Bossuyt, Luc ^a   Bosschaert, Johan ^a   Richert, Bertrand ^b   Cromphaut, Patricia ^c   Mitchell, Tim ^d   Al Abadie, Mohamed ^e   Henry, Ian ^f   Bewley, Antony ^g   Poyner, Thomas ^h   Mann, Nick ⁱ   Czernielewski, Janusz ^j  

^a Service de Dermatologie ^*  (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c Hôpital De Jumet   (Belgium)

^d Montpellier Health Centre   (United Kingdom)

^e NEW CROSS HOSPITAL   (United Kingdom)

^f Tudor House Medical Centre   (United Kingdom)

^g WHIPPS CROSS UNIVERSITY HOSPITAL   (United Kingdom)

^h Queens Park Medical Centre   (United Kingdom)

ⁱ Dermatology Department   (United Kingdom)

^j Galderma R and D   (France)

more..

Author keywords

Acne; Efficacy; Lymecycline; Minocycline; Pharmacoeconomic analysis; Safety

Indexed keywords

LYMECYCLINE; MINOCIN MR; MINOCYCLINE;

ACNE VULGARIS; ADOLESCENT; ADULT; ANTIBIOTIC THERAPY; ARTICLE; CELL COUNT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVULSION; COST EFFECTIVENESS ANALYSIS; DERMATITIS; DIARRHEA; DISEASE SEVERITY; DRUG COST; DRUG EFFICACY; DRUG RELEASE; DRUG SAFETY; DYSPEPSIA; ECONOMIC EVALUATION; FEMALE; HEADACHE; HEALTH CARE COST; HUMAN; INFLAMMATION; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MYALGIA; NAUSEA; PHARYNGITIS; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; THRUSH; URTICARIA; VAGINITIS;

ACNE VULGARIS; ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; CHILD; COST-BENEFIT ANALYSIS; ECONOMICS, PHARMACEUTICAL; FEMALE; HUMANS; LYMECYCLINE; MALE; MINOCYCLINE; SINGLE-BLIND METHOD; TREATMENT OUTCOME;

EID: 0037361037     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Sykes NL, Webster GF. Acne. A review of optimum treatment. Drugs 1994; 48: 59-70.
2. Piérard-Franchimont C, Goffin V, Arrese JE, Martalo O, Braham C, Slachmuylders P, Piérard GE. Lymecycline and minocycline in inflammatory acne. Skin Pharmacol Appl Skin Physiol 2002; 15: 112-9.
3. Cunha BA. Clinical Uses of Tetracyclines. Handbook of Experimental Pharmacology, The Tetracyclines, (J.J. Hlavka, J.H. Boothe) 1985; 78: 393-404.
4. Katsambas, A Towarky AA and Stratigos J. Topicol Clindamycine phosphate compared with oral tetracycline in the treatment of acne vulgaris. Br J Dermatol 1987; 116: 387-91.
5. Olafsson J, Gudgeirson J. Doxycycline versus Minocycline in the treatment of acne vulgaris: a double bind study. J Dermatol Treat 1989; 1: 15-7.
6. Dare S, Papworth-Smith J, Cunliffe WJ. A double blind comparison of topical clindamycin and oral minocycline in the treatment of acne vulgaris. Acta Dermatol Venerol 1990; 70: 534-7.
7. Allen JC. Minocycline. Ann Intern Med 1976; 85: 482-7.
8. Eisen D. Minocycline-induced oral hyperpigmentation. Lancet 1997; 349: 400.
9. Okada N, Sato S, Sasou T, et al. Characterisation of pigmented granules in Minocycline-induced cutoneous pigmentation: observations using fluorescence microscopy and high performance liquid chromatography. Br J Dermatol 1993; 129: 403-7.
10. Siller GM, Tod MA, Savage NW. Minocycline-induced oral pigmentation. J Am Acad Dermatol 1994; 30: 350-4.
11. Garner SE, Eady EA, Popescu C, Newton J, Li Wan Po A. Minocycline for acne vulgaris: efficacy and safety. Cochrane Database System Review (2) 2000: CD002086 (2000).
12. Cunliffe WJ, Grosshans E, Belaich S, Meynadier J, Alirezai M, Thomas LA. comparison of the efficacy and safety of lymecycline and minocycline in patients with moderately severe acne vulgaris. European Journal of Dermatology 1998; 8: 161-6 (1998).
13. Burke BM, Cunliffe WJ. The assessment of acne vulgaris - the Leeds technique. British Journal of Dermatology 1984; 3: 83-92.