Conjugated polymer-subunit immunogens and vaccines

Allergy and Clinical Immunology International

Volumn 15, Issue 2, 2003, Pages 56-61

  Petrov, Rem V ^a   Kabanov, Victor A ^b   Khaitov, Rakhim M ^a   Nekrasov, Arkadiy V ^a   Ataullakhanov, Ravshan I ^a  

^a INSTITUTE OF IMMUNOLOGY   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

4 VINYLPYRIDINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIGEN; BCG VACCINE; BRUCELLA VACCINE; CALCIUM ION; DRUG CARRIER; GRIPPOL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M; INFLUENZA VACCINE; MEMBRANE PROTEIN; POLYACRYLIC ACID; POLYELECTROLYTE; POLYMER; POTASSIUM ION; PYRIDINIUM DERIVATIVE; SHIGELLA VACCINE; SODIUM ION; TYPHOID VACCINE; VACCINE;

ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; BRUCELLA; BRUCELLOSIS; CELL INTERACTION; CELL MEMBRANE PERMEABILITY; CELLULAR IMMUNITY; CHEMICAL INTERACTION; CLINICAL PRACTICE; CYTOLOGY; DRUG CONJUGATION; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; DRUG USE; DYSENTERY; ENZYME ACTIVATION; GENETIC ANALYSIS; HELPER CELL; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOSTIMULATION; INFLUENZA; INFLUENZA VIRUS; LABORATORY TEST; LYMPHOCYTE MIGRATION; MOLECULAR MECHANICS; MYCOBACTERIUM TUBERCULOSIS; POLYMERIZATION; SALMONELLA TYPHI; SHIGELLA DYSENTERIAE; T LYMPHOCYTE; TUBERCULOSIS; TYPHOID FEVER; VACCINATION;

EID: 0037360874     PISSN: 08381925     EISSN: None     Source Type: Journal    
DOI: 10.1027/0838-1925.15.2.56     Document Type: Article

References (18)

1. Ataullakhanov RI, Khaitov RM, Petrov RV et al. Interaction of polyion molecules with plasmatic membrane of the lymphocytes differing in charged groups density on cell membrane surface (Rus). Byulleten Experimentalnoy Biologi i Meditsiny 1984; 5:588-590
2. Kabanov VA, Mustafaev MI, Norimov ASh et al. Immunogenicity of bovine serum albumin complex with polycation loaded with hydrophobic side groups (Rus). Doklady AN SSSR 1978; 243:1130-1133
3. Khaitov RM. Creation of artificial antigens and vaccines on the basis of synthetic polyelectrolytes. In Laurence Lasky (Ed.), Technological Advances in Vaccine Development. New York: Alan R. Liss, 1988, pp. 411-428
4. Khaitov RM. Vaccines based on synthetic polyions and peptides. Ann NY Acad Sci 1993; 685:788-802
5. Khaitov RM. Molecular bases for the construction of artificial immunogens and vaccines based on synthetic polyions. Allergy Proc 1995; 16:255-260
6. Khaitov RM, Nekrasov AV. Synthesis of artificial immunogens. Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya 1987; 11:3-8
7. Nekrasov AV, Berlin AA, Enikolonjan AN. Mechanisms of nitrogen-containing cyclic polymerization. J Macromol Sci Chem 1974; A 8(2):241-264
8. Nekrasov AV, Puchkova NG, Ataullakhanov RI, Ivanova AS, Khaitov RM, Petrov RV. Patent No. 2073031 (Russian Federation) for invention: "Derivates of poly-1,4-ethylenepiperazine carrying immunomodulating, antiviral and antimicrobial activities." The priority of invention: August 1990 (Rus)
9. Petrov RV, Khaitov RM. Highly immunogenic artificial complexes based on synthetic immunopotentiating polyions (artificial antigens and vaccines). Am J Reprod Immunol Microbiol 1986; 10:105-110
10. Petrov RV, Khaitov RM, Babakhin AA, Popov AN. IgE-response to allergen-polyelectrolyte complexes. Allergy Clin Immunol News 1992; 4:87-91
11. Petrov RV, Khaitov RM, Kabanov VA. Artificial antigens and vaccines based on non-natural polyelectrolytes. Sov Sci Rev D Physicochem Biol 1984; 5:277-322
12. Petrov RV, Khaitov RM, Nekrasov AV, Melnikov SY, Ataullakhanov RI, Puchkova NG, Mikheeva AV, Ivanova AS. Patent No. 1580617 (Russian Federation) for invention: "Methods of obtaining the vaccines against flu virus." The priority of invention: May 1988 (Rus)
13. Petrov RV, Khaitov RM, Norimov AS et al. Immunogenicity of conjugate obtained by covalent binding of bovine serum albumin with 4-vinyl pyridine and 4-vinyl-N-acetyl pyridinium bromide (Rus). Doklady AN SSSR 1979; 249:249-252
14. Petrov RV, Khaitov RM, Norimov ASh, Nekrasov AV, Koryakin SA. Phenotype correction of Ir-genetic control of immune response to (T,G)-A-L conjugated to synthetic polyelectrolytes. Immunol Lett 1986; 12:237-242
15. Petrov RV, Khaitov RM, Zhdanov VM, Sinyakov MS, Nekrasov AV. Infuenza virus antigen conjugated with a synthetic polyelectrolyte: a novel model of vaccines. Vaccine 1985; 3:392-400
16. Khaitov RM, Nekrasov AV, Bektemirov TA et al. Grippol vaccine study during immunization of schoolchildren (Rus). Alergiya, Astma i Klinicheskaya Immunologiya 1999; 9:7-9
17. Khaitov RM, Nekrasov AV, Bektemirov TA, Ivanova AS. Study of safety and immunoprophylactic efficacy of polymer-subunit trivalent vaccine Grippol in risk group children of various ages and adults (Rus). Alergiya, Astma i Klinicheskaya Immunologiya 2001; 1:5-7
18. Elshina GA, Gorbunov MA, Shevarli VI, Lonskaya NI, Pavlova LI, Khaitov RM, Nekrasov AV, Ivanova AS, Matrosovich MN, Puchkova NG, Belashev VP, Malinovskiy AA. Grippol polymer-subunit anti-influenza vaccine efficacy evaluation (Rus). Zhurnal Mikrobiologii, Epidemiologii i Immunobiologii